Anti-CD3 epsilon antibody (Ab5690)
CD3e, T3E, CD3E, T-cell surface glycoprotein CD3 epsilon chain, T-cell surface antigen T3/Leu-4 epsilon chain
详细信息
背景信息
Product Specifications Anti-CD3 epsilon antibody (ab5690) is a rabbit polyclonal antibody and is validated for use in IHC-P, WB in human, mouse, rat samples. Anti-CD3 epsilon antibody (ab5690) specifically detects CD3 epsilon (UniProt ID: P07766; Molecular weight: 21kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD3 epsilon antibody (ab5690) has high sensitivity and specificity. Anti-CD3 epsilon antibody (ab5690) has been cited over 548 times in peer reviewed journals and is trusted by the scientific community. Anti-CD3 epsilon antibody (ab5690) has 46 independent reviews from customers. Target Information CD3 epsilon (CD3ε) is a protein subunit of the CD3 complex, which is essential for T-cell receptor (TCR) signaling and T-cell activation. It plays a crucial role in the immune response by facilitating the recognition of antigens. CD3ε is widely used as a marker for T cells in immunological studies. Mutations or defects in CD3ε can lead to severe combined immunodeficiency (SCID), characterized by the absence of functional T cells, resulting in increased susceptibility to infections and impaired immune responses.
文献引用 (548)
Stress vesicles link epidermal mechanotransduction to stem cell differentiation.
应力囊泡将表皮力学传导与干细胞分化联系起来。
The CXCL10/CXCR3 axis is essential for sustaining immunological dormancy in triple-negative breast cancer.
CXCL10/CXCR3 轴对于维持三阴性乳腺癌的免疫休眠至关重要。
Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1β.
肝窦内皮细胞通过巨噬细胞衍生的白细胞介素-1β诱导的白细胞介素-1R1介导的趋化因子产生,促进代谢功能障碍相关的脂肪性肝炎进展。
Overactivation of Cdc42 GTPase Impairs the Cytotoxic Function of NK Cells From Old Individuals Towards Senescent Fibroblasts.
Cdc42 GTPase 过度激活会损害老年人 NK 细胞对衰老成纤维细胞的细胞毒性功能。
Safety, efficacy, and distal nerve Schwann cell biodistribution in mice and NHPs to support translation of AAV9 RNAi therapy for CMT1A.
在小鼠和非人灵长类动物中评估 AAV9 RNAi 疗法治疗 CMT1A 的安全性、有效性和远端神经雪旺细胞生物分布,以支持其转化应用。
In the diffuse large B-cell lymphoma microenvironment, SIRT1 is upregulated and correlated with a pro-inflammatory macrophage signature and autophagy-related gene expression.
在弥漫性大B细胞淋巴瘤微环境中,SIRT1 上调,并与促炎巨噬细胞特征和自噬相关基因表达相关。
Loss of Ribosomal Protein L22 (RPL22) Expression Identifies a Transcriptional Subset of MLH1-Deficient Endometrial Cancers With Lower Numbers of Tumor-Associated Lymphocytes.
核糖体蛋白 L22 (RPL22) 表达的缺失可识别出 MLH1 缺陷型子宫内膜癌的转录亚群,该亚群中肿瘤相关淋巴细胞数量较低。
Clopidogrel Administration Impairs Neurovascular Unit Recovery and Exacerbates Amyloid Beta Accumulation in Aged Mice Post-Stroke.
氯吡格雷给药会损害老年小鼠中风后的神经血管单元恢复并加剧β-淀粉样蛋白的积累。
Practical AI-based cell extraction and spatial statistics for large 3D bone marrow tissue images.
基于人工智能的大型三维骨髓组织图像的实用细胞提取和空间统计。
Enrichment of HLA-DR(+) neutrophils in osteoarthritic infrapatellar fat pad.
骨关节炎髌下脂肪垫中 HLA-DR(+) 中性粒细胞富集。
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