Anti-alpha smooth muscle Actin antibody (Ab5694)

特异性

Alpha smooth muscle actin antibody (ab5694) stains smooth muscle cells in vessel walls, gut wall, and myometrium. Myoepithelial cells in breast and salivary gland are also stained. ab5694 reacts with tumors arising from smooth muscles and myoepithelial cells.

Anti-alpha smooth muscle Actin antibody (ab5694) is a rabbit polyclonal antibody and is validated for use in IHC-P and WB. Anti-alpha smooth muscle Actin antibody (ab5694) was first used in a scientific publication in 1985 and has been cited over 3004 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-alpha smooth muscle Actin antibody (ab5694) has high sensitivity and specificity. Anti-alpha smooth muscle Actin antibody (ab5694) has 150 independent reviews from customers. Anti-alpha smooth muscle Actin antibody (ab5694) specifically detects alpha smooth muscle Actin (UniProt ID: P62736; Molecular weight: 42kDa) and is sold in 100 µg selling sizes. Alpha-Smooth Muscle Actin (α-SMA) is a critical protein involved in smooth muscle contraction, encoded by the ACTA2 gene. Predominantly found in vascular smooth muscle cells, α-SMA plays a vital role in fibrogenesis and wound healing. It is often used as a marker for myofibroblast formation, which are specialized cells that contribute to tissue repair and fibrosis. The expression of α-SMA is associated with the activation of myofibroblasts, making it an important indicator in studies of fibrosis and other related conditions.