Anti-Collagen IV antibody (Ab6586)

特异性

Some class-specific anti-collagens may be specific for three-dimensional epitopes which may result in diminished reactivity with denatured collagen or formalin-fixed, paraffin embedded tissues. This antibody reacts with most mammalian Type IV collagens and has negligible cross-reactivity with Type I, II, III, V or VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins is negligible.

Anti-Collagen IV antibody (ab6586) is a rabbit polyclonal antibody and is validated for use in ELISA, ICC/IF, IF, IHC-FoFr, IHC-Fr, IHC-FrFl, Anti-Collagen IV antibody (ab6586) was first used in a scientific publication in 2004 and has been cited over 920 times in peer reviewed journals. It's performance in IHC and Western Blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Collagen IV antibody (ab6586) has high sensitivity and specificity. Anti-Collagen IV antibody (ab6586) has 120 independent reviews from customers. Anti-Collagen IV antibody (ab6586) specifically detects Collagen IV (UniProt ID: P02462; Molecular weight: ~160kDa) and is sold in 100 µg selling sizes. Collagen IV is a key component of the extracellular matrix in tumors, contributing to tissue stiffness and promoting cancer cell invasion. It plays a significant role in tumor progression and metastasis, influencing the behaviour of cancer cells.