Anti-SOX2 antibody (Ab97959)

Anti-SOX2 antibody (ab97959) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-SOX2 antibody (ab97959) was first used in a scientific publication in 2009 and has been cited over 736 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-SOX2 antibody (ab97959) has high sensitivity and specificity. Anti-SOX2 antibody (ab97959) has 72 independent reviews from customers. Anti-SOX2 antibody (ab97959) specifically detects SOX2 (UniProt ID: P48431; Molecular weight: 35kDa) and is sold in 100 µg selling sizes. SOX2 is a crucial transcription factor in neuro research, particularly for its role in maintaining neural stem cell pluripotency and regulating neural development. It is essential for the proliferation and differentiation of neural progenitor cells, influencing brain development and repair. Researchers use SOX2 to study neural stem cell behaviour, neurogenesis and the mechanisms underlying neurodevelopmental disorders, making it vital for understanding brain development and potential regenerative therapies. Additionally, SOX2 plays a significant role in gliomas, particularly glioblastoma (GBM), the most aggressive form of brain cancer. Elevated SOX2 levels are associated with poor prognosis and tumor progression in glioblastoma patients. Targeting SOX2 expression and function is being explored as a potential therapeutic strategy to combat gliomas and improve patient outcomes.