Anti-NeuN antibody - Neuronal Marker (Ab104225)

RNA binding protein fox-1 homolog 3, Fox-1 homolog C, Neuronal nuclei antigen, NeuN antigen, RBFOX3

反应种属:Human, Mouse, Rat
抗原名称:NeuN
应用:WB, IHC, IF-FRO, IHCFl

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification
储存缓冲液Preservative: 0.03% Sodium azide Constituents: PBS, 49.98% Glycerol (glycerin, glycerine)
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

背景信息

Anti-NeuN antibody - Neuronal Marker (ab104225) is a rabbit polyclonal antibody and is validated for use in IHC-FoFr, IHC-FrFl, IHC-P, WB in human samples. Anti-NeuN antibody - Neuronal Marker (ab104225) has been cited over 252 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-NeuN antibody - Neuronal Marker (ab104225) has high sensitivity and specificity. Anti-NeuN antibody - Neuronal Marker (ab104225) has 11 independent reviews from customers. Anti-NeuN antibody - Neuronal Marker (ab104225) specifically detects NeuN (UniProt ID: A6NFN3; Molecular weight: 34kDa) and is sold in 50 µL selling sizes. NeuN (RBFOX3), a protein predominantly found in neuronal nuclei and cytoplasm, serves as a key marker for identifying neurons in research. It plays a significant role in the regulation of alternative splicing of pre-mRNA, crucial for neural development and function. Abnormalities in RBFOX3 expression have been implicated in several neurodevelopmental disorders, such as autism spectrum disorder, cognitive impairments, and epilepsy, underscoring its critical role in brain health.

文献引用 (295)

Astrocytes enable amygdala neural representations supporting memory.

星形胶质细胞使杏仁核能够形成支持记忆的神经表征。

Bukalo Olena, O'Sullivan Ruairi, Tanisumi Yuta, Mendez Adriana, Weinholtz Chase, Zimmerman Sydney, Offenberg Victoria, Carpenter Olivia, Bhagwat Hrishikesh, Mosley Sophie, O'Malley John J, Lyons Kerri, Fang Yulan, Goldschlager Jess, Ostroff Linnaea E, Penzo Mario A, Wake Hiroaki, Halladay Lindsay R, Holmes Andrew

Reduction of RAD23A extends lifespan and mitigates pathology in a mouse model of TDP-43 proteinopathy.

RAD23A 的减少可延长 TDP-43 蛋白病小鼠模型的寿命并减轻病理。

Guo Xueshui, Prajapati Ravindra Singh, Chun Jiyeon, Byun Insuk, Gebis Kamil K, Wang Yi-Zhi, Ling Karen, Dalton Casey, Blair Jeff A, Hamidianjahromi Anahid, Bachmann Gemma, Rigo Frank, Jafar-Nejad Paymaan, Savas Jeffrey N, Lee Min Jae, Sreedharan Jemeen, Kalb Robert G

Neutrophil-microglia interaction drives motor dysfunction in a neuromyelitis optica model induced by subarachnoid AQP4-IgG.

中性粒细胞-小胶质细胞相互作用导致蛛网膜下腔 AQP4-IgG 诱导的视神经脊髓炎模型出现运动功能障碍。

Qi Fangfang, Lennon Vanda A, Zhao Shunyi, Guo Yong, Ding Husheng, Liu Caiyun, Bartley Whitney M, Chen Tingjun, Lucchinetti Claudia F, Wu Long-Jun

Anti-IL-15 treatment reduces acute lentivirus inflammation and signaling in the brain.

抗IL-15治疗可减轻大脑中的急性慢病毒炎症和信号传导。

A Flupirtine Benzyl Carbamate Improves Neurocognitive Deficits and Molecular Pathology in the Cln6(nclf) Mouse.

氟吡汀苄基氨基甲酸酯可改善 Cln6(nclf) 小鼠的神经认知缺陷和分子病理。

Chaoul Victoria, Shmoury Omar, Alam Ramy, Saab Sara, Makoukji Joelle, Aridi Lynn Al, Makhoul Nadine J, Soueid Jihane, V Carmona Angelica, Simeon Princess, Trippier Paul C, Boustany Rose-Mary

Early Reprogramming Intermediates Enable Direct Neuronal Conversion Via NGN2.

早期重编程中间体可通过 NGN2 实现直接神经元转换。

Angiolillo Silvia, Qin Wei, Gesualdo Alessia, Frison Roberta, Elvassore Nicola, Laterza Cecilia, Gagliano Onelia

Protocol for the generation and xenotransplantation of human induced pluripotent stem cell-derived neural progenitor cells into the mouse forebrain

将人诱导多能干细胞衍生的神经祖细胞生成并异种移植到小鼠前脑的方案

Julie J McInvale,Chloe E Ayers,Hemanta Sarmah,Kang Kim,Peter Reinhardt,Aayushi Mahajan,Nelson Humala,Barbara Corneo,Jared Sterneckert,Peter Canoll,Gunnar Hargus

Dopaminergic action prediction errors serve as a value-free teaching signal.

多巴胺能作用预测误差可作为无价值的教学信号

Greenstreet Francesca, Vergara Hernando Martinez, Johansson Yvonne, Pati Sthitapranjya, Schwarz Laura, Lenzi Stephen C, Geerts Jesse P, Wisdom Matthew, Gubanova Alina, Rollik Lars B, Kaur Jasvin, Moskovitz Theodore, Cohen Joseph, Thompson Emmett, Margrie Troy W, Clopath Claudia, Stephenson-Jones Marcus

4D marmoset brain map reveals MRI and molecular signatures for onset of multiple sclerosis-like lesions.

4D狨猴脑图揭示了多发性硬化症样病变的MRI和分子特征。

Lin Jing-Ping, Brake Alexis, Donadieu Maxime, Lee Amanda, Smith Ginger, Hu Kevin, Nair Govind, Kawaguchi Riki, Sati Pascal, Geschwind Daniel H, Jacobson Steven, Schafer Dorothy P, Reich Daniel S

Distant origin of glioblastoma recurrence: neural stem cells in the subventricular zone serve as a source of tumor reconstruction after primary resection

胶质母细胞瘤复发的远距离起源:脑室下区的神经干细胞作为原发性切除后肿瘤重建的来源

Xue Li #, Hyun Jung Kim #, Jihwan Yoo, Yeonhee Lee, Chang Hyun Nam, Jonghan Park, Soon-Tae Lee, Tae Min Kim, Seung Hong Choi, Jae-Kyung Won, Sung-Hye Park, Young Seok Ju, Jong Bae Park, Se Hoon Kim, Jong Hee Chang, Hong-Gyun Wu, Chul-Kee Park, Jeong Ho Lee, Seok-Gu Kang, Joo Ho Lee3
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 30