Anti-BDNF antibody [EPR1292] (Ab108319)
Neurotrophic factor BDNF precursor form, proBDNF, Abrineurin, Brain-derived neurotrophic factor, BDNF
详细信息
特异性
This product may cross react with the following family members: NGF beta, neurotrophin 3, neurotrophin 4. It was discovered that this antibody exhibited weak cross - reactivity with the NTF3 protein.
背景信息
Anti-BDNF antibody [EPR1292] (ab108319) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P and WB. Anti-BDNF antibody [EPR1292] (ab108319) was first used in a scientific publication in 2012 and has been cited over 481 times in peer reviewed journals. It's performance in Western Blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-BDNF antibody [EPR1292] (ab108319) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-BDNF antibody [EPR1292] (ab108319) has 8 independent reviews from customers. Anti-BDNF antibody [EPR1292] (ab108319) specifically detects BDNF (UniProt ID: P23560; Molecular weight: 26kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR1292 - ab216443. Antibody clone EPR1292 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 555 ( ab222113, ab222321, ab305366 ). BDNF (Brain-Derived Neurotrophic Factor) is a key protein in neuro research, particularly for its role in supporting neuronal survival, growth and differentiation. It is crucial for synaptic plasticity, which underlies learning and memory. Researchers use BDNF to study neurodevelopment, neuroprotection and the effects of various interventions on brain health, making it essential for understanding both normal brain function and the pathology of neurodegenerative diseases. Its expression is highly regulated and can be influenced by factors such as exercise and stress. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (694)
Adenosine signalling drives antidepressant actions of ketamine and ECT.
腺苷信号传导驱动氯胺酮和电休克疗法的抗抑郁作用。
TNEA Regulates Hippocampal Oscillation by Improving Inhibitory Synaptic Plasticity to Ameliorates Cognitive Impairment in Alzheimer's Disease.
TNEA通过改善抑制性突触可塑性来调节海马振荡,从而改善阿尔茨海默病患者的认知障碍。
A small-molecule stabilizer of the calpastatin-calpain-2 complex restores mitochondrial function and mitigates neurodegeneration.
钙蛋白酶抑制蛋白-钙蛋白酶-2复合物的小分子稳定剂可恢复线粒体功能并减轻神经退行性变。
Late-life methionine restriction attenuates neuroinflammation in Alzheimer's disease mice via FGF21 activation in a metabolism-independent manner.
晚年限制蛋氨酸摄入可通过激活 FGF21 以代谢非依赖的方式减轻阿尔茨海默病小鼠的神经炎症。
Sex and life experience shape locus coeruleus pretangle tau pathology.
性生活和生活经历塑造了蓝斑前缠结tau蛋白病理。
Aging reduces motivation through decreased Bdnf expression in the ventral tegmental area.
衰老会降低腹侧被盖区 Bdnf 的表达,从而降低人的积极性。
Neuroprotective effects of hypidone hydrochloride (YL-0919) after traumatic brain injury in mice.
盐酸氢吡啶酮(YL-0919)对小鼠创伤性脑损伤的神经保护作用。
Therapeutic effects of low-intensity transcranial focused ultrasound stimulation on ischemic stroke in rats: An in vivo evaluation using electrical impedance tomography.
低强度经颅聚焦超声刺激对大鼠缺血性中风的治疗效果:采用电阻抗断层扫描的体内评价
Microglia overexpressing brain-derived neurotrophic factor promote vascular repair and functional recovery in mice after spinal cord injury
小胶质细胞过度表达脑源性神经营养因子可促进小鼠脊髓损伤后的血管修复和功能恢复
Neuroprotective mechanism of hydrogen sulfide in okadaic acid-induced alzheimer-like pathology.
硫化氢在冈田酸诱导的阿尔茨海默病样病理中的神经保护机制。
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