Anti-HDAC1 antibody [EPR460(2)] - Nuclear Loading Control (Ab109411)

RPD3L1, HDAC1, Histone deacetylase 1, HD1, Protein deacetylase HDAC1, Protein deacylase HDAC1

反应种属:Human, Mouse, Rat
抗原名称:HDAC1
应用:WB, IHC, FCM, IF/ICC, IP

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Stable for 12 months at -20°C
无载体蛋白No

背景信息

What is this antibody validated in? Anti-HDAC1 antibody [EPR460(2)] (ab109411) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of HDAC1? Anti-HDAC1 [EPR460(2)] (ab109411) specifically detects a band for HDAC1 (UniProt: Q13547) at a molecular weight of 55kDa. Trusted by the scientific community Anti-HDAC1 [EPR460(2)] (ab109411) was first used in a scientific publication in 2011 and has been cited over 30 times in peer-reviewed journals. Reviewed by scientists Anti-HDAC1 [EPR460(2)] (ab109411) has over 5 independent reviews from customers. Specificity confirmed The specificity of Anti-HDAC1 antibody [EPR460(2)] (ab109411) has been confirmed by Western blot testing in HDAC1 Knockout HAP1 cells. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (66)

Rapid degradation of histone deacetylase 1 (HDAC1) reveals essential roles in both gene repression and active transcription

组蛋白去乙酰化酶 1 (HDAC1) 的快速降解揭示了其在基因抑制和活性转录中的重要作用

David M English, Samuel N Lee, Khadija A Sabat, India M Baker, Trong Khoa Pham, Mark O Collins, Shaun M Cowley

Acetylation-regulated DUSP1 deficiency contributes to renal fibrosis progression.

乙酰化调控的 DUSP1 缺乏会导致肾纤维化进展

Wang Shaobo, Zhang Bo, Wang Yaqin, Lan Qigang, Lv Liangjing, Xiao Tangli, Li Yan, Yao Mengying, Zhang Jun, Wang Cheng, Huang Yinghui, Zhao Jinghong, Xiong Jiachuan

Chidamide enhances the sensitivity of gastric cancer to 5-fluorouracil chemotherapy by suppressing the HDAC3/HNF4A/TYMS axis.

西达米德通过抑制 HDAC3/HNF4A/TYMS 轴增强胃癌对 5-氟尿嘧啶化疗的敏感性。

Zhang Xiaofei, Shi Lei, Gao Yaping, Zhou Chenyi, Wang Xiyin, Shi Xiaonan

Modulation of CREB3L2-ATF4 heterodimerization via proteasome inhibition and HRI activation in Alzheimer's disease pathology.

阿尔茨海默病病理中蛋白酶体抑制和HRI激活对CREB3L2-ATF4异二聚体的调节

Herline-Killian Krystal, Pauers Michaela M, Lipponen Jessica E, Zrzavy Michael A, Gouveia Roque Cláudio, McCurdy Ethan P, Chung Kyung Min, Hengst Ulrich

Generation and validation of a novel multitarget small molecule in glioblastoma.

胶质母细胞瘤新型多靶点小分子的生成与验证

Artetxe-Zurutuza Aizpea, Iturrioz-Rodriguez Nerea, Elizazu Joseba, Toledano-Pinedo Mireia, Porro-Pérez Alicia, De Goñi Irati, Elua-Pinin Alejandro, Schäker-Hübner Linda, Azkargorta Mikel, Elortza Felix, Iriepa Isabel, Lòpez-Muñoz Francisco, Moncho-Amor Veronica, Hansen Finn K, Sampron Nicolás, Marco-Contelles Jose Luis, Matheu Ander

c-Ski is a novel repressor of NF-κB through interaction with p65 and HDAC1 in U937 cells.

c-Ski 是 U937 细胞中通过与 p65 和 HDAC1 相互作用而抑制 NF-κB 的新型抑制剂

Peng Yan, Xiong Ren-Ping, Wang Bo, Chen Xing, Ning Ya-Lie, Zhao Yan, Yang Nan, Zhang Jing, Li Chang-Hong, Zhou Yuan-Guo, Li Ping

Knockdown of RUVBL2 improves hnRNPA2/B1-stress granules dynamics to inhibit perioperative neurocognitive disorders in aged mild cognitive impairment rats

敲低 RUVBL2 可改善 hnRNPA2/B1 应激颗粒动力学,从而抑制老年轻度认知障碍大鼠围手术期神经认知障碍

Zixuan Wang, Chenyi Yang, Xinyi Wang, Huihui Liao, Xing Liu, Huan Liu, Miao Zhang, Lin Zhang, Haiyun Wang

Electroacupuncture alleviates Parkinson's disease by targeting HDAC/SIRT-mediated deacetylation of 14-3-3.

电针疗法通过靶向 HDAC/SIRT 介导的 14-3-3 去乙酰化来缓解帕金森病。

Wang Zhao-Qin, Zheng Han-Dan, Li Ling-Jie, Cao Lu-Lu, Shen Lin, Qiao Yu, Chen Yi-Yi, Wu Lu-Yi, Li Guo-Na, Wu Huan-Gan

Folic acid ameliorates placental structure and function in fetal growth restriction via epigenetic modifications.

叶酸通过表观遗传修饰改善胎儿生长受限时的胎盘结构和功能。

Gao Juanmei, Lou Yingya, He Weiwu, Xu Kaixing, Zhan Xin, Tong Jinyi, Zhai Hongbo

Electroacupuncture combined with HDAC1 inhibitor suppress tumor growth via improving the recruitment of intratumor CD8+ T cells for triple-negative breast cancer in mice

电针联合HDAC1抑制剂可通过促进肿瘤内CD8+ T细胞的募集来抑制小鼠三阴性乳腺癌的肿瘤生长。

Yehong Tian # ,Yinjie Ma # ,Xue Li ,Gang Lu ,Shixin Wang ,Xiaowei Qiu ,Xu Du
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