Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (Ab108986)
Ubiquitin carboxyl-terminal hydrolase isozyme L1, UCH-L1, Neuron cytoplasmic protein 9.5, PGP 9.5, Ubiquitin thioesterase L1, PGP9.5, UCHL1
用户验证的应用
推荐稀释比例
- IHC-P1/250 - 1/1000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000 - 1/10000
- ICC/IF1/500
- Flow Cyt (Intra)1/100 - 1/10000 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
- IP1/10 - 1/100
- IHC-Fr1/250 Heat mediated antigen retrieval using sodium citrate buffer (10mM citrate pH 6.0 + 0.05% Tween-20)
详细信息
背景信息
Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (ab108986) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, IP and WB. Abcam's high quality manufacturing and validation processes ensure Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (ab108986) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (ab108986) has been confirmed by Western Blot testing in PGP9.5 knockout ab263773 cells ( ab263773 ). Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (ab108986) has 11 independent reviews from customers. Anti-PGP9.5 antibody [EPR4118] - Neuronal Marker (ab108986) specifically detects PGP9.5 (UniProt ID: P09936; Molecular weight: 25kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR4118 - ab220823. Antibody clone EPR4118 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, Alexa Fluor ® 555, Alexa Fluor ® 488, Alexa Fluor ® 594, Alexa Fluor ® 568, APC ( ab196173, ab300549, ab302578, ab302664, ab305109, ab317591 ). PGP9.5, also known as UCH-L1/UCHL1, is a crucial protein in neuro research, particularly for its role as a neuronal and neuroendocrine marker. It is widely used to stain neuronal cell bodies and axons in both the central and peripheral nervous systems. Researchers use PGP9.5 to assess nerve fiber density and integrity, making it essential for studying neurodegenerative diseases, small fiber neuropathy and various cancers. Its reliable expression in neurons helps in evaluating neuronal health and pathology in different neurological conditions. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (159)
Hyperinnervation inhibits organ-level regeneration in mammalian skin.
过度神经支配会抑制哺乳动物皮肤的器官级再生。
TGF-β-induced fibrotic scar formation limits recovery of spinal cord injury.
TGF-β诱导的纤维化瘢痕形成限制了脊髓损伤的恢复。
Acutely denervated muscle EVs reshape neuronal mitochondrial metabolism via retrograde signaling to rescue peripheral nerve injury.
急性去神经支配的肌肉细胞外囊泡通过逆行信号传导重塑神经元线粒体代谢,从而挽救周围神经损伤。
Barrington's Nucleus: A Pontine Defecation Brain Area Exhibiting Prompt and Delayed Defecation Responses
巴林顿核:脑桥中负责排便的脑区,表现出快速和延迟的排便反应
Semaphorin 7A regulates axon outgrowth in subcutaneous white adipose tissue.
信号素 7A 调节皮下白色脂肪组织中的轴突生长。
Immune correlates underlying small fiber neuropathy presenting as vaccine-associated post-acute SARS- coronavirus syndrome.
免疫相关性小纤维神经病变表现为疫苗相关SARS冠状病毒急性后综合征。
Transcriptomic and metabolomic insights into gabapentin's therapeutic role in neurogenic inflammation of rosacea.
从转录组学和代谢组学角度深入了解加巴喷丁在玫瑰痤疮神经源性炎症中的治疗作用。
Optical coherence tomography and histological assessment of cutaneous vasculature and neural changes in long-term smokers: an exploratory study.
光学相干断层扫描和组织学评估长期吸烟者皮肤血管和神经变化:一项探索性研究。
Gastrodin alleviates bortezomib-induced peripheral neuropathy by inhibiting NF-κB/NLRP3 pathway-mediated microglial inflammation.
天麻素通过抑制 NF-κB/NLRP3 通路介导的小胶质细胞炎症来缓解硼替佐米引起的周围神经病变。
Macrophages protect against sensory axon loss in peripheral neuropathy
巨噬细胞可保护周围神经免受感觉轴突损伤
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