Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (Ab109012)

ORCA, OSIL, SQSTM1, Sequestosome-1, EBI3-associated protein of 60 kDa, Phosphotyrosine-independent ligand for the Lck SH2 domain of 62 kDa, Ubiquitin-binding protein p62, EBIAP, p60, p62

反应种属:Human, Mouse, Rat
抗原名称:SQSTM1
应用:WB, FCM, IF/ICC, IP

用户验证的应用

推荐稀释比例

  • WB1/10000 - 1/50000
  • ICC/IF1 µg/mL
  • Flow Cyt (Intra)1/10 - 1/100 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Stable for 12 months at -20°C
纯化方式Affinity purification Protein A

背景信息

Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IP and WB. Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) was first used in a scientific publication in 2014 and has been cited over 445 times in peer reviewed journals. It's performance in Western Blot in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has been confirmed by Western Blot testing in SQSTM1 / p62 knockout HEK-293T cells ( ab263770 ). Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) has 15 independent reviews from customers. Anti-SQSTM1 / p62 antibody [EPR4844] - Autophagosome Marker (ab109012) specifically detects SQSTM1 / p62 (UniProt ID: Q13501; Molecular weight: 48kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR4844 - ab219581. Antibody clone EPR4844 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, HRP, Alexa Fluor® 647, Alexa Fluor® 594, Alexa Fluor® 555, APC, PE ( ab185015, ab194720, ab194721, ab203429, ab203430, ab225093, ab225094 ). NEW: Explore our alternative host species for clone [EPR4844]: goat. SQSTM1, also known as p62, is a multifunctional scaffolding protein widely used in neuro research for its role in autophagy and protein degradation. It is upregulated in several neurodegenerative disorders, including Alzheimer's disease (AD) and amyotrophic lateral sclerosis (ALS). Researchers use SQSTM1/p62 to study the mechanisms of protein aggregation and neuroinflammation, making it essential for understanding the progression of neurodegenerative diseases and identifying potential therapeutic targets. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

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