Anti-F4/80 antibody [SP115] (Ab111101)
Emr1, Gpf480, Adgre1, Adhesion G protein-coupled receptor E1, Cell surface glycoprotein F4/80, EGF-like module receptor 1, EGF-like module-containing mucin-like hormone receptor-like 1, EMR1 hormone receptor
用户验证的应用
推荐稀释比例
- IHC-P1/50 - 1/100 Incubate primary antibody overnight at 4C. For antigen retrieval: Boil tissue section in Tris-EDTA (pH 9.0) buffer for 10 min followed by cooling at RT for 20 min. Abcam recommends using a polymer-HRP conjugated secondary for optimal signal.
详细信息
背景信息
Anti-F4/80 antibody [SP115] (ab111101) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P in mouse samples. Anti-F4/80 antibody [SP115] (ab111101) has been cited over 144 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-F4/80 antibody [SP115] (ab111101) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-F4/80 antibody [SP115] (ab111101) has 21 independent reviews from customers. Anti-F4/80 antibody [SP115] (ab111101) specifically detects F4/80 (UniProt ID: Q61549; Molecular weight: 99kDa) and is sold in a convenient trial size to enable initial testing (20 uL) and larger sizes for subsequent scaling up experiments (100 uL, 500 uL and 1 mL). Conjugation-ready, carrier free format available for antibody clone SP115 - ab24946. Anti-F4/80 antibody [SP115] (ab111101) is a clone from the portfolio of Spring Bioscience (Roche) SP clones which have been optimised for immunohistochemistry (IHC). F4/80 is a marker for murine macrophages, playing a key role in immune responses and inflammation, particularly in diseases like cancer and chronic inflammatory conditions. F4/80 is a key biomarker in chronic inflammatory conditions. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (180)
Cancer cell-intrinsic inflammasome protein ASC links innate immunity with mitochondrial metabolism in driving pancreatic cancer.
癌细胞固有炎症小体蛋白ASC将先天免疫与线粒体代谢联系起来,从而驱动胰腺癌的发生发展。
A Sensitive Reporter Mouse Model to Study Adipocyte-Derived Extracellular Vesicles In Vivo.
用于研究体内脂肪细胞衍生细胞外囊泡的敏感报告基因小鼠模型。
Hepatic supersulfides attenuate acetaminophen-induced liver injury via enhanced detoxification and anti-inflammatory mechanisms.
肝脏超硫化物通过增强解毒和抗炎机制减轻对乙酰氨基酚引起的肝损伤。
Engineered Akkermansia muciniphila vesicles for targeted pyroptosis and trained immunity to enhance immunotherapy in hepatocellular carcinoma.
利用工程改造的 Akkermansia muciniphila 囊泡进行靶向细胞焦亡和训练免疫,以增强肝细胞癌的免疫疗法。
Complement activation and M2-like macrophage accumulation in anti-MDA5 monoclonal antibody-induced hepatic injury in mice.
抗MDA5单克隆抗体诱导小鼠肝损伤中补体激活和M2样巨噬细胞聚集。
Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway.
当归-白骨药组合通过调节 Wnt/β-catenin 通路来预防葡聚糖硫酸钠诱发的结肠炎。
KLS-3021: Innovative oncolytic virotherapy for the treatment of advanced primary and metastatic cutaneous squamous cell carcinoma.
KLS-3021:用于治疗晚期原发性和转移性皮肤鳞状细胞癌的创新型溶瘤病毒疗法。
CYLD Limits Neutrophil-Driven Psoriatic Inflammation.
CYLD 可抑制中性粒细胞驱动的银屑病炎症。
Pleuromutilins Suppress Hepatocellular Carcinoma Growth via ABCA1 Inhibition-Induced Cholesterol Accumulation.
截短侧耳素通过 ABCA1 抑制诱导胆固醇积累来抑制肝细胞癌的生长。
UBE2I promotes immune infiltration and tumor progression in thyroid cancer and modulates hnRNPA2B1 SUMOylation.
UBE2I 促进甲状腺癌中的免疫浸润和肿瘤进展,并调节 hnRNPA2B1 SUMO 化。
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