Anti-GFAP antibody - Astrocyte Marker (Ab7260)

特异性

Specifically recognizes mammalian GFAP on western blots and immunocytochemically. Detects a band of 55kDa corresponding to GFAP and also a GFAP derived 48kDa band. Some customers have successfully used ab7260 on Zebrafish lysates; however we have conflicting data to suggest that not all batches will be suitable for work on Zebrafish. For further information, please contact Abcam Scientific Support.

Find all reagents to label astrocytes in our " Astrocytes markers guide ". Anti-GFAP antibody (ab7260) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC (PFA fixed), IHC-P, IP and WB. Anti-GFAP antibody (ab7260) was first used in a scientific publication in 2006 and has been cited over 1203 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-GFAP antibody (ab7260) has high sensitivity and specificity. Anti-GFAP antibody (ab7260) has 103 independent reviews from customers. Anti-GFAP antibody (ab7260) specifically detects GFAP (UniProt ID: P14136; Molecular weight: 50kDa) and is sold in 50 µL selling sizes. GFAP (Glial Fibrillary Acidic Protein) is a key marker in neuro research, particularly for its role in identifying astrocyte activity. It is predominantly expressed in astrocytes, the most abundant glial cells in the brain and spinal cord. Altered GFAP levels are associated with various neurological conditions, including Alzheimer's disease (AD), traumatic brain injury (TBI) and multiple sclerosis (MS). Researchers use GFAP to assess astrocytic response and neuroinflammation, making it essential for understanding the extent of brain injury and the progression of neurodegenerative diseases.