Anti-Collagen III antibody (Ab7778)

特异性

This antibody reacts with most mammalian Type III collagens and has expected cross-reactivity with Type I and negligible cross reactivity with Type II, IV, V or VI collagens. Non-specific cross-reaction of anti-collagen antibodies with other human serum proteins or non-collagen extracellular matrix proteins has not been tested.

Anti-Collagen III antibody (ab7778) is a rabbit polyclonal antibody and is validated for use in ELISA, ICC, ICC/IF, IHC-P, IP, WB in mouse samples. Anti-Collagen III antibody (ab7778) has been cited over 649 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Collagen III antibody (ab7778) has high sensitivity and specificity. Anti-Collagen III antibody (Colagen type 3) (ab7778) has 21 independent reviews from customers. Anti-Collagen III antibody (ab7778) specifically detects Collagen III (UniProt ID: P02461; Molecular weight: 95kDa) and is sold in 100 µg selling sizes. For more protocol tips, please see: Collagen Target Tips At least 11 genetically distinct gene products are collectively referred to as 'collagen types' or other proteins and proteoglycans of the extracellular matrix. In humans, collagens are composed of about 20 unique protein chains which under go various types of post-translational modifications and are ultimately assembled into a triple helix. This results in great diversity between collagen types. Collagens are highly conserved throughout evolution and are characterized by an uninterrupted "Glycine-X-Y" triplet repeat that is a necessary part of the triple helical structure. For these reasons it is often extremely difficult to generate antibodies with specificities to collagens. The development of type specific antibodies is dependent on NON-DENATURED three-dimensional epitopes. This preparation results in a native conformation of the protein.