Anti-alpha smooth muscle Actin antibody [1A4] (Ab7817)
ACTSA, ACTVS, GIG46, ACTA2, Alpha-actin-2, Cell growth-inhibiting gene 46 protein
用户验证的应用
推荐稀释比例
- IHC-P0.034 µg/mL Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
- WB1 µg/mL
- ICC/IF1 µg/mL
- Flow Cyt (Intra)5 µg/mL
详细信息
背景信息
Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) is a mouse monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P and WB. Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) was first used in a scientific publication in 1986 and has been cited over 1242 times in peer reviewed journals. It's performance in Western blot, immunofluorescence and IHC in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has high sensitivity and specificity. The specificity of Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has been confirmed by ICC/IF testing in alpha smooth muscle Actin knockout HeLa cells ( ab264014 ). Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) has 103 independent reviews from customers. Anti-alpha smooth muscle Actin antibody [1A4] (ab7817) specifically detects alpha smooth muscle Actin (UniProt ID: P62736; Molecular weight: 42kDa) and is sold in 100 ug and 1 mg selling sizes. Conjugation-ready, carrier free format available for antibody clone 1A4 - ab240654. Antibody clone 1A4 is also available pre-conjugated to a variety of labels for your convenience - Biotin, Alexa Fluor ® 488, Alexa Fluor ® 594, HRP, FITC ( ab12557, ab184675, ab22368, ab23696, ab8211 ). Alpha-Smooth Muscle Actin (α-SMA) is a critical protein involved in smooth muscle contraction, encoded by the ACTA2 gene. Predominantly found in vascular smooth muscle cells, α-SMA plays a vital role in fibrogenesis and wound healing. It is often used as a marker for myofibroblast formation, which are specialized cells that contribute to tissue repair and fibrosis. The expression of α-SMA is associated with the activation of myofibroblasts, making it an important indicator in studies of fibrosis and other related conditions.
文献引用 (1771)
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TLR2-PI3K/Akt 介导的微生物模拟启动增强了 GelMA 封装的 MSC 的治疗性旁分泌功能，用于糖尿病伤口再生。
Ameliorating post-infarction myocardial fibrosis and cardiac function via ROS-responsive hydrogel-mediated IL-11 antibody delivery.
通过 ROS 响应性水凝胶介导的 IL-11 抗体递送改善心肌梗死后心肌纤维化和心脏功能。
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受损的上皮细胞状态会影响T细胞介导的排斥反应后肾脏同种异体移植的存活率。
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单细胞多组学揭示了驱动肺纤维化的内皮机械敏感性 PIEZO1-IL-33 轴。
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SLPI⺠AT2-Like Cells Orchestrate Lung Adenocarcinoma Invasion via Wnt Pathway Activation and Stromal Crosstalk in a Spatially Defined Margin Niche.
SLPIâ º AT2-Like 细胞通过 Wnt 通路激活和基质串扰在空间定义的边缘微环境中协调肺腺癌侵袭。
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