Anti-Collagen I antibody [EPR22894-89] (Ab260043)
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
用户验证的应用
推荐稀释比例
- WB1/1000 Compared with ab260043, ab255809 has lower background. We recommend ab255809 as an alternative for western blotting.
- IP1/30
详细信息
背景信息
Anti-Collagen I antibody [EPR22894-89] (ab260043) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IP, WB in human, mouse, rat samples. Anti-Collagen I antibody [EPR22894-89] (ab260043) has been cited over 105 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-Collagen I antibody [EPR22894-89] (ab260043) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Collagen I antibody [EPR22894-89] (ab260043) specifically detects Collagen I (UniProt ID: P11087; Molecular weight: 95kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR22894-89 - ab26474. Collagen I (Collagen alpha-1(I) chain) modulates the tumor microenvironment by enhancing tissue rigidity and facilitating neoplastic cell proliferation. Additionally, it contributes to immune evasion by forming a structural barrier that impedes T-cell infiltration and activity. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (258)
Intravesical instillation of pirfenidone/polydopamine nanoparticles for managing neurogenic bladder post-spinal cord injury by alleviating bladder inflammation and fibrosis.
通过膀胱内灌注吡非尼酮/聚多巴胺纳米颗粒治疗脊髓损伤后神经源性膀胱,减轻膀胱炎症和纤维化。
Macrophage AMPK activated by oxidative stress drives profibrotic crosstalk with tubular cells to accelerate renal fibrosis after ischemic and reperfusion injury.
氧化应激激活的巨噬细胞 AMPK 驱动促纤维化细胞与肾小管细胞的相互作用,从而加速缺血再灌注损伤后的肾纤维化。
Macrophage NEDD4L restrains liver fibrosis by preventing scar-associated macrophage expansion via ubiquitination of phospho-SMAD3.
巨噬细胞 NEDD4L 通过泛素化磷酸化 SMAD3 来抑制瘢痕相关巨噬细胞的扩张,从而抑制肝纤维化。
GPR30-mediated NETs degradation via Trex1 in heart failure of aged female mice.
GPR30介导的NETs通过Trex1降解在老年雌性小鼠心力衰竭中的作用。
Mesenchymal stromal cells alleviate pulmonary arterial hypertension by suppressing pulmonary arterial adventitial fibroblast activation and extracellular matrix remodeling via the SOCS3/STAT3 pathway.
间充质基质细胞通过 SOCS3/STAT3 通路抑制肺动脉外膜成纤维细胞活化和细胞外基质重塑,从而缓解肺动脉高压。
Integrated Serum Pharmacochemistry, Network Pharmacology, and Transcriptomics Reveal the Mechanisms and Active Constituents of Qingfei Huoxue Decoction Against Bleomycin-Induced Pulmonary Fibrosis.
血清药理化学、网络药理学和转录组学的综合分析揭示了清肺活血汤对抗博来霉素诱导的肺纤维化的机制和活性成分。
CCN1 drives asthmatic airway remodeling through amplification of TGF-β1/Smad3 signaling.
CCN1 通过放大 TGF-β1/Smad3 信号传导来驱动哮喘气道重塑。
Monopolar Radiofrequency for Facial Hyperpigmentation Treatment: An Integrated Retrospective Clinical Trial and Ex Vivo Study.
单极射频治疗面部色素沉着过度:一项综合回顾性临床试验和体外研究。
Profibrotic predictive toxicology in the lung.
肺部促纤维化预测毒理学。
RP-182 alleviated obstruction-induced renal fibrosis by reprogramming CD206(+) macrophages.
RP-182 通过重编程 CD206(+) 巨噬细胞减轻梗阻引起的肾纤维化。
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