Anti-CD45 antibody [MEM-28] (Ab8216)

CD45, PTPRC, Receptor-type tyrosine-protein phosphatase C, Leukocyte common antigen, T200, L-CA

反应种属:Human
抗原名称:PTPRC
应用:WB, IHC, FCM, IF/ICC

详细信息

免疫原Cell preparation containing PTPRC protein. The exact immunogen used to generate this antibody is proprietary information. P08575
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.4 Preservative: 0.097% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

Human CD45 antigen (LCA). This antibody reacts with all alternative forms of CD45.

背景信息

Product Specifications Anti-CD45 antibody [MEM-28] (ab8216) is a mouse monoclonal antibody and is validated for use in Flow Cyt, ICC/IF, IHC-P, WB in human samples. Anti-CD45 antibody [MEM-28] (ab8216) specifically detects CD45 (UniProt ID: P08575; Molecular weight: 145kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-CD45 antibody [MEM-28] (ab8216) has high sensitivity and specificity. Anti-CD45 antibody [MEM-28] (ab8216) has been cited over 57 times in peer reviewed journals and is trusted by the scientific community. Related Products Antibody clone MEM-28 is also available pre-conjugated to a variety of labels for your convenience - APC, Biotin, PerCP, FITC, PE, PerCP/Cy5.5®, Alexa Fluor® 488, APC/Cy7®, PE/DyLight™ 594, Alexa Fluor® 647, PE/Cy7® ( ab28106, ab28107, ab65952, ab134199, ab134202, ab157309, ab187577, ab197130, ab223183, ab239276, ab239317 ).

文献引用 (62)

Butyrophilin 2A2 promotes T cell immunoregulation via CD45 phosphatase activation and protects against murine autoimmune glomerulonephritis and pregnancy loss.

Butyrophilin 2A2 通过 CD45 磷酸酶激活促进 T 细胞免疫调节,并能预防小鼠自身免疫性肾小球肾炎和妊娠丢失。

Alpha-ketoglutarate accelerates granulocyte-monocyte progenitor differentiation and atherosclerotic plaque inflammation via oxoglutarate receptor 1.

α-酮戊二酸通过α-酮戊二酸受体1加速粒细胞-单核细胞祖细胞分化和动脉粥样硬化斑块炎症。

Zhao Jiwei, Su Li, Li Wenhao, Lam Sin Man, Yan Cen, Zhou Taotao, Deng Yalan, Dong Yuan, Zhou Yuan, Shui Guanghou, Feng Yingmei

RASA2 deletion rescues immune synapse dysfunction, enhancing CAR T cell efficacy against DMGs.

RASA2 缺失可挽救免疫突触功能障碍,增强 CAR T 细胞对 DMG 的疗效。

Ibanez-Vega Jorge, Teis Robert, Ocasio Jennifer K, Chockley Peter, Ansari Aamir, Allo Anido Alejandro, Mehta Sanya, Meehl Michaela, Prinzing Brooke, Ward Meghan, Odde David, Baker Suzanne, Krenciute Giedre

Spatially resolved single-cell analysis of transcriptomic changes linked with neuropathic pain in human neuromas.

对人类神经瘤中与神经性疼痛相关的转录组变化进行空间分辨的单细胞分析。

Morchio Martina, Sankaranarayanan Ishwarya, Tavares-Ferreira Diana, Wong Natalie, Atkins Simon, Sher Emanuele, Price Theodore J, Lambert Daniel W, Boissonade Fiona M

Effectiveness and Safety of a Polyvinyl Alcohol Microsphere and Hyaluronic Acid Suspension for Chin Augmentation: A Randomized Controlled Trial and Multidisciplinary Study.

聚乙烯醇微球和透明质酸悬浮液用于下巴填充的有效性和安全性:一项随机对照试验和多学科研究。

Hong Wei-Jin, Ren Ji-Zhen, Wang Cheng-Yuan, Wang Shi-Wei, Zhang Kun, Chen Zhen-Yu, Zou Mu-Yan, Cao Jia-Hua, Niu Huan-Yun, Luo Sheng-Kang

Single-nucleus transcriptomics decodes the link between aging and lumbar disc herniation.

单核转录组学揭示衰老与腰椎间盘突出之间的联系

Wang Min, He Zan, Wang Anqi, Sun Shuhui, Li Jiaming, Liu Feifei, Li Chunde, Yang Chengxian, Lei Jinghui, Yu Yan, Ma Shuai, Wang Si, Zhang Weiqi, Yu Zhengrong, Liu Guang-Hui, Qu Jing

Single-cell RNA sequencing reveals a fibroblast gene signature that promotes T-cell infiltration in muscle-invasive bladder cancer

单细胞RNA测序揭示了一种成纤维细胞基因特征,该特征可促进肌层浸润性膀胱癌中的T细胞浸润。

Zige Liu # ,Xingning Mao # ,Yuli Xie # ,Yunkun Yan ,Xiang Wang ,Junhao Mi ,Hao Yuan ,Jiange Zhang ,Caisheng Huang ,Jianxin Chen ,Mujia Jili ,Shengzhu Huang ,Qingyun Zhang ,Fubo Wang ,Zengnan Mo ,Rirong Yang

Construction and application of a humanized mouse model for prostate cancer in immunotherapy.

构建和应用人源化小鼠前列腺癌免疫治疗模型。

Guo Wenwen, Li Hui, Zhao Yong, Qin Jing, Meng Han, Ge Xu, Zhang Caiqin, Shi Changhong

Forkhead box O-1 regulates the biological behavior of BMP-2-induced human bone mesenchymal stem cells through mitochondrial dynamics and autophagy.

Forkhead box O-1 通过线粒体动力学和自噬调节 BMP-2 诱导的人类骨髓间充质干细胞的生物学行为

Feng Weijia, Chen Nannan, Chen Ke, Chen Ting

Diagnosis and monitoring of breast cancer with a novel circulating tumor cells enrichment device.

利用新型循环肿瘤细胞富集装置诊断和监测乳腺癌

Gong Zhiyun, Yan Jing, Zhang Yi, Chen Yan, Li Aoshuang, Yang Xiaorong, Shi Weizhong, Guo Lin, Dai Tiantian, Dong Feng, Lu Renquan
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