用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | NK-92 cells, Recombinant protein |
| Positive IHC detected in | human tonsillitis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
IFN gamma (IFNG) is a soluble cytokine that is the only member of the type II class of IFN. It is secreted by Th1 cells, cytotoxic T cells and NK cells. The cytokine is associated with antiviral, immunoregulatory and anti-tumor properties and is a potent activator of macrophages. It plays crucial roles in pathogen clearance. Aberrant IFNG expression is associated with a number of autoinflammatory and autoimmune diseases. It has been identified in many studies as a biomarker for pleural tuberculosis (TB). Mutations in this gene are associated with aplastic anemia.
文献引用 (50)
Targeting KMT5C Suppresses Lung Cancer Progression and Enhances the Efficacy of Immunotherapy.
靶向KMT5C可抑制肺癌进展并增强免疫疗法的疗效
Ultrasound-Targeted Nanobubbles Codelivering NKP-1339 and miR-142-5p for Synergistic Mitochondrial Immunogenic Cell Death and PD-L1 Inhibition in Cancer Therapy.
超声靶向纳米气泡共递送 NKP-1339 和 miR-142-5p，用于协同诱导线粒体免疫原性细胞死亡和抑制 PD-L1 以治疗癌症
Sorafenib-loaded metal-organic framework nanoparticles for anti-hepatocellular carcinoma effects through synergistically potentiating ferroptosis and remodeling tumor immune microenvironment
索拉非尼负载的金属有机框架纳米颗粒通过协同增强铁死亡和重塑肿瘤免疫微环境发挥抗肝细胞癌作用
IFN-γ-mediated inhibition of JAK/STAT signaling via nano-scutellarin treatment is an efficient strategy for ameliorating liver fibrosis
IFN-γ 介导的纳米灯盏花素抑制 JAK/STAT 信号传导是改善肝纤维化的有效策略
Intra-cisterna-magna bevacizumab injection (ICM-BI) reproduces pathological alterations of cerebral small vessel diseases
脑池内注射贝伐单抗（ICM-BI）可重现脑小血管疾病的病理改变。
LncRNA RNF144A-AS1 gene polymorphisms and their influence on lung cancer patients in the Chinese Han population.
LncRNA RNF144A-AS1 基因多态性及其对中国汉族肺癌患者的影响
Mature tertiary lymphoid structure associated CD103+ CD8+ Trm cells determined improved anti-tumor immune in breast cancer
成熟的三级淋巴结构相关 CD103+ CD8+ Trm 细胞确定可改善乳腺癌的抗肿瘤免疫
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Decorin 的过表达可优化脐带间充质干细胞治疗博来霉素诱导的大鼠肺纤维化的疗效
Itraconazole inhibits the Wnt/β-catenin signaling pathway to induce tumor-associated macrophages polarization to enhance the efficacy of immunotherapy in endometrial cancer.
伊曲康唑抑制 Wnt/β-catenin 信号通路，诱导肿瘤相关巨噬细胞极化，从而增强子宫内膜癌免疫疗法的疗效
Molecular Subtyping and Therapeutic Targeting of IFNG-Driven Immunogenic Cell Death in Lung Adenocarcinoma
肺腺癌中 IFNG 驱动的免疫原性细胞死亡的分子亚型和治疗靶向
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