Beta Tubulin Polyclonal antibody (10068-1-AP)
Tubulin beta 3 chain; Tubulin beta III; β III tubulin; βIII tubulin; TUBB4
用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | HeLa cells, mouse cerebellum tissue, mouse brain tissue, rat brain tissue, HEK-293 cells, Jurkat cells, HepG2 cells, A431 cells, NIH/3T3 cells |
| Positive IP detected in | HEK-293 cells |
| Positive IHC detected in | rat brain tissue, human brain tissue, mouse brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF/ICC detected in | C2C12 cells, HepG2 cells |
| Positive FC (Intra) detected in | HeLa cells |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
There are five tubulins in human cells: alpha, beta, gamma, delta, and epsilon. Tubulins are conserved across species. They form heterodimers, which multimerize to form a microtubule filament. An alpha and beta tubulin heterodimer is the basic structural unit of microtubules. The heterodimer does not come apart, once formed. The alpha and beta tubulins, which are each about 55 kDa MW, are homologous but not identical. Alpha, beta, and gamma tubulins have all been used as loading controls. Tubulin expression may vary according to resistance to antimicrobial and antimitotic drugs.
文献引用 (221)
Lithocholic acid phenocopies anti-ageing effects of calorie restriction
石胆酸具有与热量限制类似的抗衰老作用。
Lithocholic acid binds TULP3 to activate sirtuins and AMPK to slow down ageing
石胆酸与TULP3结合，激活sirtuins和AMPK，从而延缓衰老。
Unravelling cysteine-deficiency-associated rapid weight loss.
揭开半胱氨酸缺乏症相关快速减肥的秘密
Simvastatin overcomes the pPCK1-pLDHA-SPRINGlac axis-mediated ferroptosis and chemo-immunotherapy resistance in AKT-hyperactivated intrahepatic cholangiocarcinoma.
辛伐他汀可克服 AKT 过度激活的肝内胆管癌中 pPCK1-pLDHA-SPRINGlac 轴介导的铁死亡和化疗免疫疗法耐药性
Inhibition of ARH2 by pH/ROS-responsive nanosystem for improved lung adenocarcinoma immunochemotherapy.
利用 pH/ROS 响应纳米系统抑制 ARH2 以改善肺腺癌免疫化疗
Delivering LINE1 antisense oligonucleotides via endothelial targeting extracellular vesicles to ameliorate myocardial infarction-induced cardiac senescence.
通过内皮细胞靶向细胞外囊泡递送 LINE1 反义寡核苷酸，以改善心肌梗死引起的心脏衰老
Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer.
NSD3 在 DNA 复制压力中的亚型特异性功能赋予前列腺癌细胞对 PARP 抑制剂的耐药性
S100P is a ferroptosis suppressor to facilitate hepatocellular carcinoma development by rewiring lipid metabolism
S100P 是一种铁死亡抑制剂，通过重新连接脂质代谢来促进肝细胞癌的发展
Genetic code expansion reveals site-specific lactylation in living cells reshapes protein functions
遗传密码扩展揭示活细胞中位点特异性乳酸化重塑蛋白质功能
Buddleoside alleviates nonalcoholic steatohepatitis by targeting the AMPK-TFEB signaling pathway
布德洛苷通过靶向AMPK-TFEB信号通路缓解非酒精性脂肪性肝炎
- 1
- 2
- 3
- 4
- 5
- 6
- 23