CD9 Polyclonal antibody (20597-1-AP)
5H9; 5H9 antigen; BA2; BTCC 1; CD9 antigen
用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | HCT 116 cells, HEK-293 cells, HeLa cells, L02 cells, HEK-293-derived exosomes |
| Positive IHC detected in | human lung cancer tissue, human breast cancer tissue, human endometrial cancer tissue, human ovary cancer tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | human ovary cancer tissue |
| Positive IF/ICC detected in | MCF-7 cells |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
The cell-surface molecule CD9, a member of the transmembrane-4 superfamily, interacts with the integrin family and other membrane proteins, and is postulated to participate in cell migration and adhesion. Expression of CD9 enhances membrane fusion between muscle cells and promotes viral infection in some cells (PMID:10459022). It is often used as a mesenchymal stem cell marker (PMID:18005405). The CD9 antigen appears to be a 227-amino acid molecule with four hydrophobic domains and one N-glycosylation site (PMID: 1840589). This antibody detects bands of 23-30 kDa, it may be due to the difference of glycosylations (PMID: 8701996).
文献引用 (115)
Injectable ECM-mimetic dynamic hydrogels abolish ferroptosis-induced post-discectomy herniation through delivering nucleus pulposus progenitor cell-derived exosomes
可注射的 ECM 模拟动态水凝胶通过递送髓核祖细胞衍生的外泌体来消除铁死亡诱导的椎间盘切除术后疝。
Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.
Arf1 缺失神经元中有害脂质的积累通过释放 mtDNA 和激活小胶质细胞中的炎症通路促进神经退行性变
DDX5 super-enhancer promotes vasculogenic mimicry formation and metastasis in nasopharyngeal carcinoma by enhancing ADAM10 transcription.
DDX5 超级增强子通过增强 ADAM10 转录促进鼻咽癌的血管生成拟态形成和转移
ATG7-deficient fibroblast promotes breast cancer progression via exosome-mediated downregulation of SCARB1.
ATG7 缺陷的成纤维细胞通过外泌体介导的 SCARB1 下调促进乳腺癌进展
Blocking the SIRPα-CD47 axis promotes macrophage phagocytosis of exosomes derived from visceral adipose tissue and improves inflammation and metabolism in mice
阻断SIRPα-CD47轴可促进巨噬细胞吞噬内脏脂肪组织来源的外泌体，并改善小鼠的炎症和代谢。
Physically engineered extracellular vesicles targeted delivering miR-21-5p to promote renoprotection after renal ischemia-reperfusion injury
物理工程改造的细胞外囊泡靶向递送 miR-21-5p 以促进肾缺血再灌注损伤后的肾脏保护
Extracellular vesicular delivery of ceramides from pulmonary macrophages to endothelial cells facilitates chronic obstructive pulmonary disease
神经酰胺从肺巨噬细胞通过细胞外囊泡输送到内皮细胞，促进慢性阻塞性肺病
MRO/HNRNPU/CCL5 feedback loop amplifies M2 macrophage and breast cancer cell crosstalk to drive progression.
MRO/HNRNPU/CCL5 反馈回路增强 M2 巨噬细胞和乳腺癌细胞之间的相互作用，从而推动疾病进展
S-Adenosylmethionine Inhibits Plasminogen-Activating Inhibitor-1 and Protects Male Mice From FOLFOX-Induced Liver Injury.
S-腺苷甲硫氨酸抑制纤溶酶原激活抑制剂-1，保护雄性小鼠免受FOLFOX诱导的肝损伤
Mesenchymal stem cells protect the integrity of the alveolar epithelial barrier through extracellular vesicles by inhibiting MAPK-mediated necroptosis.
间充质干细胞通过细胞外囊泡抑制 MAPK 介导的坏死性凋亡，从而保护肺泡上皮屏障的完整性
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