Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (Ab8978)
Vimentin, VIM
用户验证的应用
推荐稀释比例
- IHC-P1/100 - 1/1000 We recommend ab92547 as an alternative for IHC-P with mouse samples.
- ICC/IF1 µg/mL
- Flow Cyt (Intra)1/100 - 1/200
- IHC-FrRecommended range is 1/100 - 1/200 for Immunohistochemistry with avidin-biotinylated horseradish peroxidase complex (ABC) as detection. For PFA fixed tissue use at 1/1000.
详细信息
背景信息
Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) is a mouse monoclonal antibody and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, WB in mouse samples. Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) has been cited over 570 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) has high sensitivity and specificity. The specificity of Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) has been confirmed by testing in knockout samples. Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) has 44 independent reviews from customers. Anti-Vimentin antibody [RV202] - Cytoskeleton Marker (ab8978) specifically detects Vimentin (UniProt ID: P08670; Molecular weight: 54kDa) and is sold in 100 µg selling sizes. Antibody clone RV202 is also available pre-conjugated to FITC for your convenience ( ab128507 ). Vimentin (57 kDa) is the intermediate filament protein (IFP) of mesenchymal cells. This IFP however often deviates from the tissue-specific and developmentally regulated pattern of expression. Besides its typical expression in most cultured cells, vimentin is also expressed together with several other IFPs during early stages of development. As differentiation proceeds, vimentin is exchanged for the tissue-specific intermediate filament type. Also in cancers, vimentin is often expressed in addition to the tissue-specific IFP. RV202 is a mouse monoclonal IgG1 antibody derived by fusion of SP2/0-Ag14 mouse myeloma cells with spleen cells from a BALB/c mouse immunized with a cytoskeletal vimentin extract of calf lens.
文献引用 (619)
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Blocking AREG-EGFR signaling attenuates pan-arterial fibrosis in chronic cardiac allograft rejection.
阻断 AREG-EGFR 信号传导可减轻慢性心脏移植排斥反应中的全动脉纤维化。
OTUD1 delays wound healing by regulating endothelial function and angiogenesis in diabetic mice.
OTUD1 通过调节糖尿病小鼠的内皮功能和血管生成来延缓伤口愈合。
Degradable scaffold-mediated synergistic matrix formation by endogenous cells: an in vivo manufacturing strategy for off-the-shelf vascular grafts to address clinical shortages.
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Sympathetic nerve aggravates autoimmune skin disease via NE-adrenergic receptor axis: Neuroimmune cross-talk insights from vitiligo.
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HK2-driven histone H3K18 lactylation promotes stromal cell senescence and decidualization deficiency in URSA via CUX1-mediated SASP factor transcription.
HK2 驱动的组蛋白 H3K18 乳酸化通过 CUX1 介导的 SASP 因子转录促进 URSA 中的基质细胞衰老和蜕膜化缺陷。
Zinc-Releasing Fibrous Scaffolds Modulate Fibroblast, Endothelial, and Macrophage Interactions for Vascularized Tissue Engineering.
锌释放纤维支架调节成纤维细胞、内皮细胞和巨噬细胞的相互作用,用于血管化组织工程。
PTN/IGF-2 signaling modulates endometrial decidualization and immune cell trafficking to facilitate pregnancy maintenance.
PTN/IGF-2 信号传导调节子宫内膜蜕膜化和免疫细胞迁移,从而促进妊娠维持。
Plasma extracellular vesicles-derived MicroRNAs as potential biomarkers in idiopathic pulmonary fibrosis.
血浆细胞外囊泡衍生的微RNA作为特发性肺纤维化的潜在生物标志物。
Lipoxin B4 Mitigates TRPV4-Activated Müller Cell Gliosis During Ocular Hypertension.
脂氧素 B4 可减轻眼高压期间 TRPV4 激活的 Müller 细胞胶质增生。
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