IL-6 Polyclonal antibody (21865-1-AP)
IL6; B-cell stimulatory factor 2; IFN-beta-2; IL 6; Interferon beta-2
用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | LPS and Protein transport inhibitor treated HUVEC cells |
| Positive IP detected in | LPS and Protein transport inhibitor treated HUVEC cells |
| Positive IF/ICC detected in | LPS and Brefeldin A treated HUVEC cells |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
Interleukin-6 (IL-6) is an interleukin that acts as both a pro-inflammatory and anti-inflammatory cytokine. IL-6 protein is secreted by a variety of cell types including T cells and macrophages as phosphorylated and variably glycosylated molecule. IL-6 plays an essential role in the final differentiation of B-cells into Ig-secreting cells involved in lymphocyte and monocyte differentiation. It induces myeloma and plasmacytoma growth and induces nerve cells differentiation acts on B-cells, T-cells, hepatocytes, hematopoietic progenitor cells and cells of the CNS. IL-6 is also considered a myokine, a cytokine produced from muscle, and is elevated in response to muscle contraction. IL-6 has been shown to interact with interleukin-6 receptor and glycoprotein 130. Additionally, IL-6 is involved in hematopoiesis, bone metabolism, and cancer progression, and has been defined an essential role in directing transition from innate to acquired immunity.
文献引用 (192)
Panaxatriol exerts anti-senescence effects and alleviates osteoarthritis and cartilage repair fibrosis by targeting UFL1.
人参三醇通过靶向 UFL1 发挥抗衰老作用，缓解骨关节炎和软骨修复纤维化
TRAF7 knockdown induces cellular senescence and synergizes with lomustine to inhibit glioma progression and recurrence.
TRAF7 敲低可诱导细胞衰老，并与洛莫司汀协同抑制胶质瘤的进展和复发
Integrated proteogenomic characterization of ampullary adenocarcinoma.
壶腹腺癌的整合蛋白质基因组学特征分析
Absence of astrocytic ceruloplasmin reverses the senescence process with aging of learning and memory abilities.
星形胶质细胞铜蓝蛋白的缺失会逆转衰老过程中学习和记忆能力的衰退过程
Mesoporous Prussian blue nanoparticle neuroconduit for the biological therapy targeting oxidative stress reduction, inflammation inhibition, and nerve regeneration
介孔普鲁士蓝纳米粒子神经导管用于针对氧化应激减少、炎症抑制和神经再生的生物治疗
Engineered decellularized tendon hydrogel with sustained zinc ion release orchestrates anti-inflammatory microenvironment and functional regeneration in Achilles tendinopathy.
具有持续释放锌离子的工程化脱细胞肌腱水凝胶可调控抗炎微环境并促进跟腱病的功能再生
Thalidomide mitigates Crohn's disease colitis by modulating gut microbiota, metabolites, and regulatory T cell immunity.
沙利度胺通过调节肠道菌群、代谢物和调节性 T 细胞免疫来缓解克罗恩病结肠炎
Automated and Enclosed Three-Dimensional Biofabrication System for Mesenchymal Stem Cell Culture to Enhance Diabetic Wound Healing
用于间充质干细胞培养以促进糖尿病伤口愈合的自动化封闭式三维生物制造系统
IL-6 decodes sex and diet-dependent circadian and metabolic rhythms.
IL-6 可解码与性别和饮食相关的昼夜节律和代谢节律
USC-Derived Small Extracellular Vesicles-Functionalized Scaffolds Promote Scarless Vaginal Defect Repair via Delivery of Decorin and DUSP3 Proteins
USC 衍生的小细胞外囊泡功能化支架通过递送 Decorin 和 DUSP3 蛋白促进无瘢痕阴道缺损修复
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