用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive WB detected in | human placenta tissue, pig spleen tissue |
| Positive IP detected in | human placenta tissue |
| Positive IHC detected in | human placenta tissue, human liver tissue, human lung tissue, human tonsillitis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | human tonsillitis tissue, human liver tissue, human placenta tissue, human lung cancer tissue |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
CD163 is a transmembrane protein which belongs to the scavenger receptor cysteine-rich (SRCR) superfamily. This protein is a scavenger receptor for the hemoglobin-haptoglobin complex and is a marker for monocytes and macrophages. Soluble CD163 (sCD163), as a result of ectodomain shedding during inflammatory activation of macrophages, circulates in blood and has been suggested as a plasma/serum marker for macrophage activity.
文献引用 (92)
Microenvironment-feedback regulated hydrogels as living wound healing materials.
微环境反馈调控水凝胶作为活体伤口愈合材料
Excessive MYC Orchestrates Macrophages induced Chromatin Remodeling to Sustain Micropapillary-Patterned Malignancy in Lung Adenocarcinoma.
MYC 过量调控巨噬细胞诱导的染色质重塑，以维持肺腺癌中的微乳头状恶性肿瘤
Inhibiting inflammation in adipocytes accelerates mammary tumor development in mice
抑制脂肪细胞炎症会加速小鼠乳腺肿瘤的发生发展。
Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration.
弹性蛋白样多肽和三氯生修饰的PCL膜在组织再生中提供无菌保护
N-Lactoyl-Phenylalanine modulates lipid metabolism in microglia/macrophage via the AMPK-PGC1α-PPARγ pathway to promote recovery in mice with spinal cord injury.
N-乳酰苯丙氨酸通过 AMPK-PGC1α-PPARα 通路调节小胶质细胞/巨噬细胞的脂质代谢，从而促进脊髓损伤小鼠的恢复
Platelet Membrane and miR-181a-5p Doubly Optimized Nanovesicles Enhance Cardiac Repair Post-Myocardial Infarction through Macrophage Polarization.
血小板膜和 miR-181a-5p 双重优化纳米囊泡通过巨噬细胞极化增强心肌梗死后的心脏修复
ELAVL1-mediated USP29 mRNA degradation activates TAK1 driving M1 microglial polarization and neural stem cell differentiation dysregulation in spinal cord injury.
ELAVL1 介导的 USP29 mRNA 降解激活 TAK1，驱动脊髓损伤中的 M1 小胶质细胞极化和神经干细胞分化失调
YTHDF1-mediated m6A modification of GBP4 promotes M1 macrophage polarization in acute lung injury
YTHDF1 介导的 GBP4 m6A 修饰促进急性肺损伤中的 M1 巨噬细胞极化
The RNF8/OPTN/KDM6A axis controls macrophage polarization to maintain testicular microenvironment homeostasis
RNF8/OPTN/KDM6A轴控制巨噬细胞极化以维持睾丸微环境稳态
Sanren decoction ameliorates ulcerative colitis by modulating gut microbiota and macrophage polarization to enhance intestinal barrier function.
三仁汤通过调节肠道菌群和巨噬细胞极化来增强肠道屏障功能，从而改善溃疡性结肠炎
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