用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive IHC detected in | rat cerebellum tissue, human brain tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | rat cerebellum tissue, mouse cerebellum tissue, rat brain tissue |
| Positive FC (Intra) detected in | SH-SY5Y cells |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
NeuN, encoded by FOX3, is a neuron-specific nuclear protein. Anti-NeuN stains exclusively neuronal cells in the central and peripheral nervous systems, especially postmitotic and differentiating neurons, as well as terminally differentiated neurons. Anti-NeuN has been used widely as a reliable tool to detect most postmitotic neuronal cell types. The immunohistochemical staining is primarily localized in the nucleus of the neurons with lighter staining in the cytoplasm.
文献引用 (62)
Chromogranin A deficiency attenuates tauopathy by altering epinephrine-alpha-adrenergic receptor signaling in PS19 mice.
嗜铬粒蛋白 A 缺乏通过改变 PS19 小鼠的肾上腺素-α-肾上腺素能受体信号传导来减轻 tau 蛋白病
Targeting MAD2B as a strategy for ischemic stroke therapy.
以 MAD2B 为靶点治疗缺血性卒中
Engineered endoplasmic reticulum-targeting nanodrugs with Piezo1 inhibition and promotion of cell uptake for subarachnoid hemorrhage inflammation repair.
工程化内质网靶向纳米药物，通过抑制 Piezo1 和促进细胞摄取来修复蛛网膜下腔出血炎症
FOXO3a-BAP1 axis regulates neuronal ferroptosis in early brain injury after subarachnoid hemorrhage.
FOXO3a-BAP1轴调节蛛网膜下腔出血后早期脑损伤中的神经元铁死亡
Exercise-induced irisin ameliorates cognitive impairment following chronic cerebral hypoperfusion by suppressing neuroinflammation and hippocampal neuronal apoptosis.
运动诱导的鸢尾素通过抑制神经炎症和海马神经元凋亡来改善慢性脑低灌注后的认知障碍
Deubiquitination of RIPK3 by OTUB2 potentiates neuronal necroptosis after ischemic stroke
OTUB2介导的RIPK3去泛素化增强缺血性卒中后的神经元坏死性凋亡。
The homozygous LRRK2.p.N1437D point mutation mouse is a novel model of parkinsonism.
纯合LRRK2.p.N1437D点突变小鼠是一种新型帕金森病模型
Inhibiting ceramide synthase 5 expression in microglia decreases neuroinflammation after spinal cord injury
抑制小胶质细胞中神经酰胺合酶 5 的表达可减少脊髓损伤后的神经炎症
Spatial proteomics reveals distinct protein patterns in cortical migration disorders caused by LIN28A overexpression and WNT activation.
空间蛋白质组学揭示了由 LIN28A 过表达和 WNT 激活引起的皮质迁移障碍中独特的蛋白质模式
Senolytic Treatment Attenuates Global Ischemic Brain Injury and Enhances Cognitive Recovery by Targeting Mitochondria.
衰老细胞清除疗法通过靶向线粒体减轻全脑缺血性损伤并增强认知恢复
- 1
- 2
- 3
- 4
- 5
- 6
- 7