CD81 Monoclonal antibody (66866-1-Ig)

26 kDa cell surface protein TAPA-1; CD81 antigen; CD81 molecule; S5.7

反应种属:Human
抗原名称:CD81
应用:WB, IHC, ELISA, IF-P
标记:Unconjugated

用户验证的应用

经验证应用

项目详情
Positive WB detected inRaji cells, HCT 116 cells, HEK-293 cells, Jurkat cells, LPS treated THP-1 cells, Ramos cells, Daudi cells
Positive IHC detected inhuman tonsillitis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF-P detected inhuman tonsillitis tissue

推荐稀释说明

It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.

详细信息

免疫原CatNo: Ag27298 Product name: Recombinant human CD81 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 114-199 aa of BC002978 Sequence: VNKDQIAKDVKQFYDQALQQAVVDDDANNAKAVVKTFHETLDCCGSSTLTALTTSVLKNNLCPSGSNIISNLFKEDCHQKIDDLFS
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品类型Antibody
产品形式Liquid
偶联物Unconjugated
纯化方式Protein G purification
储存缓冲液PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
RRIDAB_2882203

背景信息

CD81 (also known as TAPA1 or TSPAN28) is a membrane protein of the tetraspanin superfamily, which are characterized by the presence of four conserved transmembrane regions. Many of these members are expressed on leukocytes and have been implicated in signal transduction, cell-cell interactions, and cellular activation and development. CD81 is involved in signal transduction and cell adhesion in the immune system (PMID: 9597125). CD81 has also been identified as en essential receptor for HCV (hepatitis C virus) (PMID: 21428934).

文献引用 (64)

A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids.

一种功能可调的磁性纳米链平台,用于对超痕量生物流体中的细胞外囊泡进行 N-糖蛋白组学分析

Li Mingyang, Song Xiaorong, Tu Haixia, Sun Jie, Deng Yuanyuan, Wang Bing, Cai Yuhan, Wang Yulian, Li Bin, Wang Yue, Zhang Xiangzheng, Wei Dong, Yang Xiaoyu, Guo Yueshuai, Li Xiang, Gu Jie, Ni Jie, Zhou Yifan, Gu Zhongze, Xie Zhuoying, Li Yan, Guo Xuejiang

Accumulation of Damaging Lipids in the Arf1-Ablated Neurons Promotes Neurodegeneration through Releasing mtDNA and Activating Inflammatory Pathways in Microglia.

Arf1 缺失神经元中有害脂质的积累通过释放 mtDNA 和激活小胶质细胞中的炎症通路促进神经退行性变

Li Xu, Jin Shuhan, Wang Danke, Wu Ying, Tang Xiaoyu, Liu Yufan, Yao Tiange, Han Shoufa, Sun Lin, Wang Yuetong, Hou Steven X

An anti-FAP-scFv-functionalized exosome-carrying hydrogel delivers SKI mRNA to fibrotic nucleus pulposus cells to alleviate intervertebral disc degeneration by regulating FOXO3.

一种抗FAP-scFv功能化的外泌体携带水凝胶将SKI mRNA递送至纤维化髓核细胞,通过调节FOXO3来缓解椎间盘退变

Li Yueyang, Zhai Yu, Wang Tianling, Wang Siya, Tian Yu, Bian Zhiqun, Zhang Yang, Zhang Chao, Liu Minghan, Li Changqing

Endogenous retrovirus-like proteins recruit UBQLN2 to stress granules and shape their functional biology

内源性逆转录病毒样蛋白募集UBQLN2至应激颗粒并塑造其功能生物学特性。

Harihar M Mohan ,Martin G Fernandez ,Camellia Huang ,Rita Lin ,Jaimie H Ryou ,Donald Seyfried ,Nikolas Grotewold ,Anna J Barget ,Alexandra M Whiteley ,Venkatesha Basrur ,Shyamal Mosalaganti ,Henry L Paulson ,Lisa M Sharkey

CD81(+) senescent-like fibroblasts exaggerate inflammation and activate neutrophils via C3/C3aR1 axis in periodontitis.

CD81(+)衰老样成纤维细胞通过C3/C3aR1轴加剧牙周炎的炎症并激活中性粒细胞

Fu Liangliang, Yin Chenghu, Zhao Qin, Guo Shuling, Shao Wenjun, Xia Ting, Sun Quan, Chen Liangwen, Li Jinghan, Wang Min, Xia Haibin

Endothelial extracellular vesicle miR-423-5p regulates microvascular homeostasis and renal function after ischemia-reperfusion injury

内皮细胞外囊泡 miR-423-5p 在缺血再灌注损伤后调节微血管稳态和肾功能。

Francis Migneault ,Hyunyun Kim ,Alice Doreille ,Shanshan Lan ,Alexis Gendron ,Marie-Hélène Normand ,Annie Karakeussian Rimbaud ,Martin Dupont ,Isabelle Bourdeau ,Éric Bonneil ,Julie Turgeon ,Sylvie Dussault ,Pierre Thibault ,Mélanie Dieudé ,Éric Boilard ,Alain Rivard ,Héloïse Cardinal ,Marie-Josée Hébert

Triptolide targets PPP2CA/ITGA5 axis to suppress lactate-driven ovarian cancer progression.

雷公藤内酯醇靶向 PPP2CA/ITGA5 轴,抑制乳酸驱动的卵巢癌进展

Ding Ling, Chen Wutao, Luo Cenxin, Weygant Nathaniel, Lai Yi, Ru Dan, Liu Hengan, Wang You, Li He

Exosomal SphK1 from colorectal cancer cells promotes cancer cell migration and activates hepatic stellate cells.

结直肠癌细胞的外泌体SphK1促进癌细胞迁移并激活肝星状细胞

Zhang Wenlu, Xu Chunyan

Identifying plasma exosome antigens as a potential diagnostic biomarker for tuberculosis disease

鉴定血浆外泌体抗原作为结核病的潜在诊断生物标志物

Yan Jiang, Li Yan, Baoru Zhou, Jianming Hong, Huixing Tan, Xiaonan Li, Yong Wang

Establishment of an Assay with Ultrahigh Sensitivity for Detecting sEV-Derived PD-L1 as a Serum Biomarker for Lung Cancer-A Pilot Study Using TN-cyclon™.

建立检测 sEV 衍生 PD-L1 作为肺癌血清生物标志物的超高灵敏度检测方法——使用 TN-cyclon™ 的试点研究

Okita Kyo, Arita Hasumi, Sudo Keita, Yoshimura Teruki, Ito Etsuro
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