Anti-Mitofusin 2 antibody [NIAR164] (Ab124773)

CPRP1, KIAA0214, MFN2, Mitofusin-2, Transmembrane GTPase MFN2

反应种属:Human, Mouse, Rat
抗原名称:MFN2
应用:WB, IHC, IF/ICC

用户验证的应用

推荐稀释比例

  • IHC-P1/50 - 1/100 Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
  • WB1/1000 - 1/10000
  • ICC/IF1/300 For unpurified, use 1/100 - 1/250.

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-Mitofusin 2 antibody [NIAR164]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Stable for 12 months at -20°C
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-Mitofusin 2 antibody [NIAR164] (ab124773) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Mitofusin 2? Anti-Mitofusin 2 [NIAR164] (ab124773) specifically detects a band for Mitofusin 2 (UniProt: O95140) at a molecular weight of 86kDa. Trusted by the scientific community Anti-Mitofusin 2 [NIAR164] (ab124773) was first used in a scientific publication in 2012 and has been cited over 80 times in peer-reviewed journals. Reviewed by scientists Anti-Mitofusin 2 [NIAR164] (ab124773) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-Mitofusin 2 antibody [NIAR164] (ab124773) has been confirmed by Western blot testing in MFN2 Knockout HEK-293 cells. Other related products We have a range of other formats of antibody clone [NIAR164] also available for your convenience: ab124773, Carrier free - ab219730 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (144)

VAMP7-dependent late endosomal secretion of ER and mitochondrial proteins impacts the tumor microenvironment and macrophage engagement.

VAMP7 依赖的内质网和线粒体蛋白的晚期内体分泌会影响肿瘤微环境和巨噬细胞的参与。

Vats Somya, Dionisio Pedro, Lemercier Quentin, Pineau Raphael, Therreau Ludivine, Lipecka Joanna, Cholley Béatrice, Moog Jean-Baptiste, Wojnacki Jose, Keime Céline, Zala Diana, Bun Philippe, Freire Sofia, Domingues Neuza, Danglot Lydia, Guerrera Ida Chiara, Delevoye Cédric, Chevet Eric, Raimundo Nuno, Galli Thierry

A preclinical candidate of cyclophilin D inhibition improves alcohol-associated liver injury.

环孢菌素 D 抑制剂的临床前候选药物可改善酒精相关性肝损伤。

Che Zhaoyi, Luo Zhihui, Xiao Dong, Ma Fashu, Zhou Haoxiong, Song Yali, Guo Shanshan, Yuan Yuan, Wang Hao, Mak Ching-Pong, So Kwok-Fai, Xiao Jia

Parkin protects against traumatic brain injury through regulating mitochondrial quality control.

帕金蛋白通过调节线粒体质量控制来保护大脑免受创伤性损伤。

Wu Xiuquan, Lv Weihao, Chen Hongqing, Fu Yihao, Fei Xiaowei, Dou Yanan, Luo Peng, Yu Yang, Niu Zhanfeng, Huan Yu, Wei Jialiang, Zhang Jimeng, Ji Chenchen, Li Sanzhong, Zhou Yuefei, Yuan Yunchao, Chao Wangshu, Luo Yaowen, Xie Changcai, Qiang Yujie, Chang Hao, Gao Dakuan, Li Xia

ZEB1 maintains mitochondrial fission and macrophage efferocytosis by restraining MFN2, thereby limiting inflammation and improving tendon‑bone healing.

ZEB1 通过抑制 MFN2 来维持线粒体分裂和巨噬细胞吞噬作用,从而限制炎症并改善肌腱骨愈合。

Zhao Yan, Zhang Yuankai, Lei Tian, Zhang Shangqing, Nan Kai, Zhang Xin, Fan Li-Hong

Integrated transcriptomic analysis and experimental validation identify ACADL as a mitochondrial tumor suppressor via the FOXO3a/PUMA axis in lung adenocarcinoma.

整合转录组分析和实验验证表明,ACADL 通过 FOXO3a/PUMA 轴在肺腺癌中发挥线粒体肿瘤抑制作用。

Wang Ying, Ding Yan

Forsythiaside A inhibits the progression of intrahepatic cholangiocarcinoma partially via suppressing oxidative stress-induced hepatic stellate cell activation and macrophage polarization.

连翘苷A通过抑制氧化应激诱导的肝星状细胞活化和巨噬细胞极化,部分抑制肝内胆管癌的进展。

Zhang Shiyu, Du Fan, Liao Ye, Zhang Chuyu, Zhang Meixia

Cadmium-Induced Mitochondrial and MAMs Dysregulation in Rat Testis: The Protective Role of D-Aspartate.

镉诱导大鼠睾丸线粒体和 MAMs 失调:D-天冬氨酸的保护作用。

Latino Debora, Falvo Sara, Venditti Massimo, Santillo Alessandra, Grillo Giulia, Chieffi Baccari Gabriella, Messaoudi Imed, Di Fiore Maria Maddalena

Voltage-gated sodium channel 1.8 contributes to hyperalgesia induced by the coexistence of anxiety and remifentanil exposure.

电压门控钠通道 1.8 可导致焦虑和瑞芬太尼暴露同时存在时引起的痛觉过敏。

Cai Jinxia, Chen Linyao, Wang Yanan, Ye Jianwen, Xu Zixuan, Gao Linglin, Zhou Zijun, Sun Jiehao

Effect of Denervation on Skeletal Muscle Mitochondria in Heterozygous mtDNA Mutator Mice.

去神经支配对杂合子 mtDNA 突变小鼠骨骼肌线粒体的影响。

Shirai Takanaga, Hanakita Hideto, Takeda Kohei, Kitaoka Yu, Ishikawa Kaori, Nakada Kazuto, Takemasa Tohru

The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.

IDO1 在肺纤维化中的关键作用:从肺成纤维细胞线粒体融合和靶向分子抑制的角度

Wang Lei, Ge Shanchun, Zhang Ye, Feng Deqin, Zhu Ting, Zhang Louqian, Zhang Chaofeng
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