CD9 Monoclonal antibody (60232-1-Ig)

CD9 antigen; BTCC 1; BA2; 5H9 antigen; 5H9

反应种属:Human
抗原名称:CD9
应用:WB, IHC, ELISA, IF/ICC, IF-P
标记:Unconjugated

用户验证的应用

经验证应用

项目详情
Positive WB detected inA431 cells, HeLa cells
Positive IHC detected inhuman ovary tumor tissue, human breast cancer tissue, human colon cancer tissue, human tonsillitis tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0
Positive IF-P detected inhuman breast cancer tissue, human ovary tumor tissue, human lung cancer tissue
Positive IF/ICC detected inMCF-7 cells

推荐稀释说明

It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.

详细信息

免疫原CatNo: Ag14529 Product name: Recombinant human CD9 protein Source: e coli.-derived, PET28a Tag: 6*His Domain: 100-208 aa of BC011988 Sequence: FAIEIAAAIWGYSHKDEVIKEVQEFYKDTYNKLKTKDEPQRETLKAIHYALNCCGLAGGVEQFISDICPKKDVLETFTVKSCPDAIKEVFDNKFHIIGAVGIGIAVVMI
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品类型Antibody
产品形式Liquid
偶联物Unconjugated
纯化方式Protein G purification
储存缓冲液PBS with 0.02% sodium azide and 50% glycerol, pH 7.3.
储存条件Store at -20°C. Stable for one year after shipment. Aliquoting is unnecessary for -20 o C storage.
RRIDAB_11232215

背景信息

The cell-surface molecule CD9, a member of the transmembrane-4 superfamily, interacts with the integrin family and other membrane proteins, and is postulated to participate in cell migration and adhesion. Expression of CD9 enhances membrane fusion between muscle cells and promotes viral infection in some cells (PMID:10459022). It is often used as a mesenchymal stem cell marker (PMID:18005405). CD9 is also known as the p24 antigen besides MIC3, TSPAN29 because it is a protein of molecular weight 24 kD. The CD9 antigen appears to be a 227-amino acid molecule with 4 hydrophobic domains and 1 N-glycosylation site.

文献引用 (43)

A functionally tunable magnetic nanochains platform for N-glycoproteomic analysis of extracellular vesicles from ultratrace biofluids.

一种功能可调的磁性纳米链平台,用于对超痕量生物流体中的细胞外囊泡进行 N-糖蛋白组学分析

Li Mingyang, Song Xiaorong, Tu Haixia, Sun Jie, Deng Yuanyuan, Wang Bing, Cai Yuhan, Wang Yulian, Li Bin, Wang Yue, Zhang Xiangzheng, Wei Dong, Yang Xiaoyu, Guo Yueshuai, Li Xiang, Gu Jie, Ni Jie, Zhou Yifan, Gu Zhongze, Xie Zhuoying, Li Yan, Guo Xuejiang

Abnormal α-synuclein binds to synaptotagmin 13, impairing extracellular vesicle release in synucleinopathies.

异常的α-突触核蛋白与突触结合蛋白13结合,损害突触核蛋白病中的细胞外囊泡释放

Miki Yasuo, Shimoyama Shuji, Tanaka Makoto T, Kushibiki Hanae, Nakahara Asa, Wen Xiaopeng, Hijioka Masanori, Kon Tomoya, Murthy Megha, Furukawa Tomonori, Bettencourt Conceição, Mori Fumiaki, Mizukami Hiroki, Takahashi Shirushi, Tada Mari, Kitamura Yoshihisa, Kakita Akiyoshi, Warner Thomas T, Wakabayashi Koichi

(124)I-labelled BMSC-Derived Extracellular Vesicles Deliver CRISPR/Cas9 Ribonucleoproteins With a GFP-Reporter System to Inhibit Osteosarcoma Proliferation and Metastasis.

(124)I标记的BMSC衍生细胞外囊泡递送带有GFP报告系统的CRISPR/Cas9核糖核蛋白,以抑制骨肉瘤增殖和转移

Pan Yujie, Yang Xianteng, Zeng Zhirui, Liu Futao, Luo Jin, Shen Mao, Zhou Wei, Li Jianyang, Jiang Guangfu, Sun Li, Huang Haifeng, Pan Runsang

Tumor exosomal circPTBP3 drives gastric cancer peritoneal metastasis via mesothelial-mesenchymal transition.

肿瘤外泌体 circPTBP3 通过间皮-间质转化驱动胃癌腹膜转移

Dong Chao, Zhou Yajing, Shen Xiaochun, Hu Shuo, Duan Kaipeng, Chen Tao, Li Weikang, Sun Xiaotong, Li Peiyuan, Wang Pengbo, Han Ye, Li Dongbao, Zhi Qiaoming, Zhou Jin

A New Histology-Based Prognostic Index for Acute Myeloid Leukemia: Preliminary Results for the "AML Urayasu Classification".

急性髓系白血病新的基于组织学的预后指数:“AML Urayasu 分类”的初步结果

Mitsumori Toru, Nitta Hideaki, Takizawa Haruko, Iizuka-Honma Hiroko, Furuya Chiho, Fujishiro Maki, Tomita Shigeki, Hashizume Akane, Sawada Tomohiro, Miyake Kazunori, Okubo Mitsuo, Sekiguchi Yasunobu, Ando Miki, Noguchi Masaaki

Exosomal miR-222-3p derived from dermal papilla cells inhibits melanogenesis in melanocytes by targeting SOX10 in rabbits

来自真皮乳头细胞的外泌体 miR-222-3p 通过靶向兔子的 SOX10 抑制黑素细胞中的黑素生成

Yang Chen, Tingting Lu, Yingying Dai, Yu Xue, Bohao Zhao, Xinsheng Wu

The 8-oxoguanine DNA glycosylase-synaptotagmin 7 pathway increases extracellular vesicle release and promotes tumour metastasis during oxidative stress

8-氧鸟嘌呤 DNA 糖基化酶-突触蛋白 7 通路增加细胞外囊泡释放并在氧化应激期间促进肿瘤转移

Ying Ma, Jiarong Guo, Haipeng Rao, Jingyu Xin, Xinyi Song, Rui Liu, Shan Shao, Jiajia Hou, Liyu Kong, Zhigang Hu, Lingfeng He, Feiyan Pan, Zhigang Guo

Ultrasound targeted microbubble destruction assisted exosomal delivery of siHmox1 effectively inhibits doxorubicin-induced cardiomyocyte ferroptosis.

超声靶向微泡破坏辅助外泌体递送siHmox1可有效抑制阿霉素诱导的心肌细胞铁死亡

Chen Jianmei, Qiu Shuo, Liu Yang, Sun Wenqi, Zhou Tian, Zhao Lianbi, Li Zhelong, Duan Yunyou

Proteomic Profiling of Serum Extracellular Vesicles Identifies Diagnostic Signatures and Therapeutic Targets in Breast Cancer

血清细胞外囊泡的蛋白质组学分析可识别乳腺癌的诊断特征和治疗靶点

Ganfei Xu #, Rui Huang #, Reziya Wumaier #, Jiacheng Lyu, Minjing Huang, Yaya Zhang, Qingjian Chen, Wenting Liu, Mengyu Tao, Junjian Li, Zhonghua Tao, Bo Yu, Erxiang Xu, Lingfeng Wang, Guoying Yu, Olivier Gires, Lei Zhou, Wei Zhu, Chen Ding, Hongxia Wang

Fluorogenic RNA-based biomaterials for imaging and tracking the cargo of extracellular vesicles.

用于成像和追踪细胞外囊泡货物的荧光RNA基生物材料

Bonacquisti Emily E, Ferguson Scott W, Wadsworth Gable M, Jasiewicz Natalie E, Wang Jinli, Chaudhari Ameya P, Kussatz Caden C, Nogueira Ana T, Keeley Daniel P, Itano Michelle S, Bolton Matthew L, Hahn Klaus M, Banerjee Priya R, Nguyen Juliane
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