用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| Positive IHC detected in | human tonsillitis tissue, human appendicitis tissue, human colon cancer tissue, human liver cancer tissue, human lung cancer tissue, human urothelial carcinoma tissue Note: suggested antigen retrieval with TE buffer pH 9.0; (*) Alternatively, antigen retrieval may be performed with citrate buffer pH 6.0 |
| Positive IF-P detected in | human tonsillitis tissue |
推荐稀释说明
It is recommended that this reagent should be titrated in each testing system to obtain optimal results. Sample-dependent, Check data in validation data gallery.
详细信息
背景信息
CD68 is a type I transmembrane glycoprotein that is highly expressed by human monocytes and tissue macrophages. It belongs to the lysosomal/endosomal-associated membrane glycoprotein (LAMP) family and primarily localizes to lysosomes and endosomes with a smaller fraction circulating to the cell surface. CD68 is also a member of the scavenger receptor family. It may play a role in phagocytic activities of tissue macrophages.
文献引用 (41)
Deubiquitinase JOSD2 alleviates colitis by inhibiting inflammation via deubiquitination of IMPDH2 in macrophages.
去泛素化酶 JOSD2 通过去泛素化巨噬细胞中的 IMPDH2 来抑制炎症，从而缓解结肠炎
Microneedle delivery of CAR-M-like engineered macrophages alleviates intervertebral disc degeneration through enhanced efferocytosis capacity
微针递送CAR-M样工程化巨噬细胞可通过增强胞吞作用缓解椎间盘退变
Self-assembled extracellular matrix-lipid nanoparticle composite for site-specific siRNA delivery to improve cardiac repair post-myocardial infarction.
自组装细胞外基质-脂质纳米颗粒复合材料用于定点siRNA递送，以改善心肌梗死后的心脏修复
SPP1 (+) macrophages in colorectal cancer: Markers of malignancy and promising therapeutic targets.
结直肠癌中的 SPP1 (+) 巨噬细胞：恶性肿瘤的标志物和有前景的治疗靶点
Comprehensive multiomics analysis identifies PYCARD as a key pyroptosis-related gene in osteoarthritis synovial macrophages.
综合多组学分析发现 PYCARD 是骨关节炎滑膜巨噬细胞中与细胞焦亡相关的关键基因
Pharmacological targeting cGAS/STING/NF-κB axis by tryptanthrin induces microglia polarization toward M2 phenotype and promotes functional recovery in a mouse model of spinal cord injury
色胺酮对 cGAS/STING/NF-κB 轴的药理靶向作用可诱导小胶质细胞向 M2 表型极化，并促进脊髓损伤小鼠模型的功能恢复
Single-cell sequencing analysis reveals cancer-associated pericyte subgroup in esophageal squamous cell carcinoma to predict prognosis
单细胞测序分析揭示食管鳞状细胞癌中癌症相关的周细胞亚群以预测预后
Human efferent ductules and epididymis display unique cell lineages with motile and primary cilia.
人类输出小管和附睾具有独特的细胞谱系，具有运动纤毛和初级纤毛
Overexpression of Decorin Optimizes the Treatment Efficacy of Umbilical Cord Mesenchymal Stem Cells in Bleomycin-Induced Pulmonary Fibrosis in Rats.
Decorin 的过表达可优化脐带间充质干细胞治疗博来霉素诱导的大鼠肺纤维化的疗效
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