Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (Ab1220)
H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, H3C1, H3FC, HIST1H3C, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l, H3K9me2, H3K9me, H3K9
详细信息
特异性
By peptide ELISA ab1220 recognizes di methyl K9, but not unmodified K9, mono methyl K9, tri methyl K9, di methyl K27, tri methyl K27, mono methyl K4, di methyl K4 or tri methyl K4. By Western blot ab1220 is blocked by di methyl K9, but not by unmodified K9, mono methyl K9, tri methyl K9, di methyl K27, tri methyl K27, mono methyl K4, di methyl K4 or tri methyl K4. This indicates the specificity of ab1220 for di methyl K9 of Histone H3.
背景信息
Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) is a House Mouse Monoclonal antibody and is validated for use in ChIP, Dot, ELISA, ICC/IF, IHC-P, WB in human samples. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has been cited over 961 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has high sensitivity and specificity. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) has 71 independent reviews from customers. Anti-Histone H3 (di methyl K9) antibody [mAbcam 1220] - ChIP Grade (ab1220) specifically detects Histone H3 Di Methyl-K9 (UniProt ID: P68431; Molecular weight: 15kDa) and is sold in 100 ug selling sizes. Antibody clone mAbcam 1220 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 488, Alexa Fluor® 647 ( ab62168, ab2385, ab23851). Histone H3 (di methyl K9), also known as H3K9me2, is an important epigenetic modification associated with gene silencing and heterochromatin formation. This anti histone H3 antibody detecting H3K9me2 is an essential tool for studying this modification's role in transcriptional repression and chromatin structure. Abnormal H3K9me2 levels are linked to various diseases, including cancer and neurological disorders. Monitoring di methyl K9 modifications can provide valuable insights into disease mechanisms and potential therapeutic targets. Learn about ChIP assay kits, other ChIP antibodies, and more in the ChIP assay guide. ChIP protocols ChIP protocol for cross-linking ChIP (X-ChIP) Native ChIP protocol Chromatin preparation from tissues for ChIP ChIP troubleshooting ChIP tips and tricks guide Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com
文献引用 (928)
CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1.
通过 CRISPR 筛选人类胰腺癌异种移植瘤,发现 KLF5 增殖脆弱性与表观遗传修饰因子 NCAPD2 和 MTHFD1 有关。
CBFA2T2: a novel H3K27 reader regulating metabolism and tumor growth.
CBFA2T2:一种新型的 H3K27 阅读器,可调节代谢和肿瘤生长。
Mutation in HER1 enhances stigma exsertion and hybrid seed production in rice.
HER1基因突变可增强水稻柱头伸出和杂交种子生产。
A SET domain-containing protein and HCF-1 maintain transgenerational epigenetic memory.
SET结构域蛋白和HCF-1维持跨代表观遗传记忆。
G9a-mediated H3K9me2 orchestrates intestinal epithelial regeneration through epigenetic silencing of cell cycle-related genes.
G9a 介导的 H3K9me2 通过表观遗传沉默细胞周期相关基因来调控肠上皮再生。
TP53BP2 Promotes Placental Autophagy and Preeclampsia via G9a and DNMT1 Cooperatively Modulating E2F1.
TP53BP2 通过 G9a 和 DNMT1 协同调节 E2F1 促进胎盘自噬和先兆子痫。
Developmental stage dominates cell-type identity and reveals a chromatin regulatory function for Rad50 in Drosophila.
发育阶段决定细胞类型特性,并揭示果蝇中 Rad50 的染色质调控功能。
Gut microbiota modulation of epigenetic target EHMT2: Lacticaseibacillus rhamnosus Fb7-311 regulated renal cell carcinoma apoptosis and metastasis.
肠道菌群对表观遗传靶标 EHMT2 的调控:鼠李糖乳杆菌 Fb7-311 调节肾细胞癌的凋亡和转移。
Augmented CENH3 loading is accompanied by transcriptional and epigenetic reprogramming at rice centromeres during meiosis.
在水稻减数分裂过程中,CENH3 的增加伴随着着丝粒的转录和表观遗传重编程。
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