Anti-IGF2BP2/IMP-2 antibody [EPR6741(B)] (Ab124930)

IMP2, VICKZ2, IGF2BP2, Insulin-like growth factor 2 mRNA-binding protein 2, IGF2 mRNA-binding protein 2, IMP-2, Hepatocellular carcinoma autoantigen p62, IGF-II mRNA-binding protein 2, VICKZ family member 2

反应种属:Human, Mouse, Rat
抗原名称:IGF2BP2
应用:WB, IHC, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle|Stable for 12 months at -20°C
无载体蛋白No

背景信息

What is this antibody validated in? Anti-IGF2BP2/IMP-2 antibody [EPR6741(B)] (ab124930) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of IGF2BP2/IMP-2? Anti-IGF2BP2/IMP-2 [EPR6741(B)] (ab124930) specifically detects a band for IGF2BP2/IMP-2 (UniProt: Q9Y6M1) at a molecular weight of 66kDa. Trusted by the scientific community Anti-IGF2BP2/IMP-2 [EPR6741(B)] (ab124930) was first used in a scientific publication in 2012 and has been cited over 20 times in peer-reviewed journals. Other related products We have a range of other formats of antibody clone [EPR6741(B)] also available for your convenience: ab124930, Carrier free - ab246342, Alexa Fluor ® 488 - ab319129, Alexa Fluor ® 647 - ab322024 Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (61)

LINC01963 promotes pancreatic ductal adenocarcinoma proliferation via METTL3/IGF2BP2 axis-mediated m⁶A modification of c-Myc.

LINC01963 通过 METTL3/IGF2BP2 轴介导的 mâ ¶C-Myc 修饰促进胰腺导管腺癌增殖。

Liu Qixian, Li Ruiyu, Liu Bohan, Liu Hangqi, Shi Xuqing, Yin Xianglin, Ju Xinping, Zhang Sichong, Wang Jun, Zhang Yuhan, Liu Xiaoding, Li Dongmei, Chen Longyun, Niu Yamei, Wu Huanwen, Liang Zhiyong

O-GlcNAcylation of IGF2BP2 promotes angiogenesis after ischemic stroke by stabilizing PPP2CA in an m6A-dependent manner : O-GlcNAcylation of IGF2BP2 alleviates ischemic brain injury.

IGF2BP2 的 O-GlcNAc 化通过以 m6A 依赖的方式稳定 PPP2CA 来促进缺血性中风后的血管生成:IGF2BP2 的 O-GlcNAc 化可减轻缺血性脑损伤。

The circ_0042103/TAF15/NER axis regulates inflammation and DNA damage in pulpitis.

circ_0042103/TAF15/NER 轴调节牙髓炎中的炎症和 DNA 损伤。

Lai Feng, Zhang Jingkun, Lin Liecong, Dong Huixian, Li Meizhen, Zhong Jialin, Li Yuhong, Li Yang, Chen Wei, Wang Bingtao, Chen Xuan, Lin Li, Jiang Yiguo, Jiang Qianzhou

Acute myeloid leukemia (AML)-derived bone mesenchymal stem cell exosomal METTL14 promotes AML cell growth and glycolysis by HOXA3/WNT7B axis.

急性髓系白血病 (AML) 来源的骨髓间充质干细胞外泌体 METTL14 通过 HOXA3/WNT7B 轴促进 AML 细胞生长和糖酵解。

Liu Wanying, Ming Xi, Wu Jiaying, Yan Sijia, Su Shuai, Zheng Rubing, Wang Yu, Xiao Yi

Direct circMAN1A2(2,3,4,5)-CENPB mRNA interaction regulates cell proliferation and cancer progression.

circMAN1A2(2,3,4,5)-CENPB mRNA 直接相互作用调节细胞增殖和癌症进展。

Cao Mei, Yuan Guo-Hua, Cao Shi-Meng, Liu Yu-Xin, Liu Chu-Xiao, Xu Yi-Feng, Wei Jia, Guo Yi-Lin, Chen Ling-Ling, Yang Li

N 6-Methyladenosine modification of circDcbld2 in Kupffer cells promotes hepatic fibrosis via targeting miR-144-3p/ Et-1 axis

库普弗细胞中 circDcbld2 的 N6-甲基腺苷修饰通过靶向 miR-144-3p/Et-1 轴促进肝纤维化

Sai Zhu, Xin Chen, Lijiao Sun, Xiaofeng Li, Yu Chen, Liangyun Li, Xiaoguo Suo, Chuanhui Xu, Minglu Ji, Jianan Wang, Hua Wang, Lei Zhang, Xiaoming Meng, Cheng Huang, Jun Li

SNORA37/CMTR1/ELAVL1 feedback loop drives gastric cancer progression via facilitating CD44 alternative splicing

SNORA37/CMTR1/ELAVL1 反馈回路通过促进 CD44 可变剪接驱动胃癌进展

Banghe Bao #, Minxiu Tian #, Xiaojing Wang #, Chunhui Yang #, Jiaying Qu, Shunchen Zhou, Yang Cheng, Qiangsong Tong, Liduan Zheng

RNA-binding proteins hnRNPM and ELAVL1 promote type-I interferon induction downstream of the nucleic acid sensors cGAS and RIG-I

RNA 结合蛋白 hnRNPM 和 ELAVL1 促进核酸传感器 cGAS 和 RIG-I 下游的 I 型干扰素诱导

Alexander Kirchhoff, Anna-Maria Herzner, Christian Urban, Antonio Piras, Robert Düster, Julia Mahlberg, Agathe Grünewald, Thais M Schlee-Guimarães, Katrin Ciupka, Petro Leka, Robert J Bootz, Christina Wallerath, Charlotte Hunkler, Ann Kristin de Regt, Beate M Kümmerer, Maria Hønholt Christensen, Flo

Circ-ITCH promotes the ubiquitination degradation of HOXC10 to facilitate osteogenic differentiation in disuse osteoporosis through stabilizing BRCA1 mRNA via IGF2BP2-mediated m(6)A modification.

Circ-ITCH 通过 IGF2BP2 介导的 m(6)A 修饰稳定 BRCA1 mRNA,从而促进 HOXC10 的泛素化降解,进而促进废用性骨质疏松症中的成骨分化

Zhong Da, Li Xi, Yin Zhen, Chen Peng, Li Yusheng, Tian Jian, Wang Long, Liu Hua, Yin Ke, Zhu Lemei, Kong Lingyu, Chen Kunli, Li Yaochun, Hong Chungu, Wang Chenggong

METTL3-mediated m6A modification of circCDKAL1 regulates macrophage M1 polarization and nasal epithelial cell barrier function in allergic rhinitis through IGF2BP2/JARID2/HMGB1 axis.

METTL3 介导的 circCDKAL1 的 m6A 修饰通过 IGF2BP2/JARID2/HMGB1 轴调节过敏性鼻炎中的巨噬细胞 M1 极化和鼻上皮细胞屏障功能

Zhan Jiabin, Luo Dan, Fu Yunlong, Zhou Yu, Li Rui, Wei Xin
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