Anti-CPT1A antibody [8F6AE9] (Ab128568)

CPT1, CPT1A, CPT1-L, Carnitine palmitoyltransferase 1A, Succinyltransferase CPT1A, CPT I, CPTI-L

反应种属:Human, Mouse, Rat
抗原名称:CPT1A
应用:WB, IHC, ELISA, FCM, IF/ICC

用户验证的应用

推荐稀释比例

  • IHC-P0.5 µg/mL Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • WB1 µg/mL
  • ICC/IF0.5-5 µg/mL
  • In-Cell ELISA0.1-1 µg/mL

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Mouse / IgG2b
抗体类型Monoclonal
全称Anti-CPT1A antibody [8F6AE9]
产品形式Liquid
储存缓冲液pH: 7.4 - 7.5 Preservative: 0.02% Sodium azide Constituents: HEPES buffered saline
储存条件运输条件: Blue Ice 推荐的短期储存条件: +4°C 推荐的长期储存条件: +4°C 储存信息: Do Not Freeze
纯化方式Precipitation Ammonium Sulphate

背景信息

Anti-CPT1A antibody [8F6AE9] (ab128568) is a House Mouse Monoclonal antibody and is validated for use in Flow Cyt, ICC/IF, IHC-P, In-Cell ELISA, WB in human, rat samples. Anti-CPT1A antibody [8F6AE9] (ab128568) has been cited over 179 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality validation processes ensure Anti-CPT1A antibody [8F6AE9] (ab128568) has high sensitivity and specificity. The specificity of Anti-CPT1A antibody [8F6AE9] (ab128568) has been confirmed by testing in knockout samples. Anti-CPT1A antibody [8F6AE9] (ab128568) has 5 independent reviews from customers. Anti-CPT1A antibody [8F6AE9] (ab128568) specifically detects CPT1A (UniProt ID: P50416; Molecular weight: 88kDa) and is sold in 100 ug selling sizes. Antibody clone 8F6AE9 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, HRP ( ab171449, ab198494 ). CPT1A is crucial in fatty acid oxidation, and its dysfunction is linked to metabolic disorders, diabetic nephropathy, and certain cancers This monoclonal antibody to CPT1A has been knockout validated in Western blot. The expected band for CPT1A was observed in wild type cells and the band was not seen in CPT1A knockout cells. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

文献引用 (218)

Acetylation of fatty acid synthase regulates microglial lipid droplets accumulation and pro-inflammatory activity following traumatic brain injury.

脑外伤后,脂肪酸合成酶的乙酰化作用调节小胶质细胞脂滴的积累和促炎活性。

Mup3 ameliorates the dysregulation of glucose and lipid metabolism in MAFLD.

Mup3 可改善 MAFLD 中的葡萄糖和脂质代谢紊乱。

Zhang Xiao-Min, Gao Jing-Ya, Wang Dong, Wei Xiang, Lin Li, Xie Xin-Rui, Gao Han, Wang Xiu-Yun, Hua Hong-Ting, Xu Yong-Xia, Zhang Lei, Gao Chao-Bing, Zhang Hua-Bing

Cross-species hepatic transcriptomics identify conserved immune-metabolic reprogramming in acute-on-chronic liver failure progression.

跨物种肝脏转录组学揭示了急性加慢性肝衰竭进展过程中保守的免疫代谢重编程。

Chen Panyu, Song Yun, Lin Xiao, Zeng Zhaokai, Su Wenxi, Ren Yunyun, Wang Chen, He Kang, Shi Min, Wang Yugang

Alpha-1 Antitrypsin Protects Against Cisplatin-Induced Acute Kidney Injury by Restoring Redox and Mitochondrial Homeostasis.

α1-抗胰蛋白酶通过恢复氧化还原和线粒体稳态来保护肾脏免受顺铂引起的急性肾损伤。

Kim Mina, Oh Se-Hyun, Han Jin, Ahn Ji-Sun, Oh Eun-Joo, Jung Hee-Yeon, Choi Ji-Young, Cho Jang-Hee, Park Sun-Hee, Kim Chan-Duck, Kim Yong-Lim, Jeon You Hyun, Lim Jeong-Hoon

Altered Carnitine Homeostasis Modulates Hyperosmolarity-Induced Mitochondrial Dysfunction and Lipotoxicity in Human Corneal Epithelial Cells.

肉碱稳态改变调节高渗诱导的人类角膜上皮细胞线粒体功能障碍和脂毒性。

Kontoh-Twumasi Richard, Aliste Antonella, Scheid Alexander, Lax Karina, Glass Joshua, Sharma Ashok, Sharma Shruti

UCP2-Driven Fatty Acid Oxidation Promotes Macrophage M2 Polarization and Renal Fibrosis.

UCP2驱动的脂肪酸氧化促进巨噬细胞M2极化和肾纤维化。

Wang Xingyue, Li Yuxi, Li Liu, Gu Xinyan, Dai Chunsun, Jiang Lei

Spatial transcriptomic clocks reveal cell proximity effects in brain ageing

空间转录组时钟揭示大脑衰老中的细胞邻近效应

Eric D Sun, Olivia Y Zhou, Max Hauptschein, Nimrod Rappoport, Lucy Xu, Paloma Navarro Negredo, Ling Liu, Thomas A Rando, James Zou #, Anne Brunet #4

AMP-activated protein kinase-driven lipid droplet dynamics govern melanoma sensitivity to polyunsaturated fatty acid and iron-induced ferroptosis.

AMP激活的蛋白激酶驱动的脂滴动力学决定了黑色素瘤对多不饱和脂肪酸和铁诱导的铁死亡的敏感性。

Motamedi Sahar, Ravoet Nina, Dehairs Jonas, Vanderhoydonc Frank, Escamilla-Ayala Abril, Sliwinska Malgorzata A, Wang Shuncong, Idkowiak Jakub, Soenen Stefaan, Agostinis Patrizia, Marine Jean-Christophe, Swinnen Johannes V

Copy number amplification of FLAD1 promotes the progression of triple-negative breast cancer through lipid metabolism

FLAD1 拷贝数扩增通过脂质代谢促进三阴性乳腺癌进展

Xiao-Qing Song #, Tian-Jian Yu #, Yang Ou-Yang #, Jia-Han Ding, Yi-Zhou Jiang, Zhi-Ming Shao, Yi Xiao

The transcriptional repressor HEY2 regulates mitochondrial oxidative respiration to maintain cardiac homeostasis

转录抑制因子HEY2调节线粒体氧化呼吸以维持心脏稳态

Peilu She #,Bangjun Gao #,Dongliang Li #,Chen Wu #,Xuejiao Zhu,Yuan He,Fei Mo,Yao Qi,Daqing Jin,Yewei Chen,Xin Zhao,Jinzhong Lin,Hairong Hu,Jia Li,Bing Zhang,Peng Xie,Chengqi Lin,Vincent M Christoffels,Yueheng Wu,Ping Zhu,Tao P Zhong
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