Anti-Fatty Acid Synthase antibody [EPR7466] (Ab128870)

FAS, FASN, Fatty acid synthase, Type I fatty acid synthase

反应种属:Human, Mouse, Rat
抗原名称:FASN
应用:WB, IHC, FCM, IF/ICC, IP

用户验证的应用

推荐稀释比例

  • IHC-P1/450 Perform heat-mediated antigen retrieval with citrate buffer pH 6 before commencing with IHC staining protocol.
  • WB1/10000 This antibody does not work well in liver tissue in WB application. We suggest ab128856 as an alternative.
  • ICC/IF1/250 - 1/500
  • Flow Cyt (Intra)1/50 - 1/69250 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
  • IP1/30

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-Fatty Acid Synthase antibody [EPR7466]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-Fatty Acid Synthase antibody [EPR7466] (ab128870) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Intra), Immunoprecipitation (IP), Immunohistochemistry (IHC-P), Immunocytochemistry/immunofluorescence (ICC/IF) in Human, Mouse, Rat samples. What is the molecular weight of Fatty Acid Synthase? Anti-Fatty Acid Synthase [EPR7466] (ab128870) specifically detects a band for Fatty Acid Synthase (UniProt: P49327) at a molecular weight of 273kDa. Trusted by the scientific community Anti-Fatty Acid Synthase [EPR7466] (ab128870) was first used in a scientific publication in 2012 and has been cited over 50 times in peer-reviewed journals. Specificity confirmed The specificity of Anti-Fatty Acid Synthase antibody [EPR7466] (ab128870) has been confirmed by Western blot testing in FASN Knockout HAP1 cells. Other related products We have a range of other formats of antibody clone [EPR7466] also available for your convenience: ab128870, HRP - ab196854, Carrier free - ab221934, APC - ab319329, PE - ab319466, Alexa Fluor® 647 - ab319690, Alexa Fluor® 594 - ab319822, Alexa Fluor® 555 - ab319963, Alexa Fluor® 750 - ab321016 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 20µl. Discover our selection of trial-size antibodies.

文献引用 (99)

Acetylation of fatty acid synthase regulates microglial lipid droplets accumulation and pro-inflammatory activity following traumatic brain injury.

脑外伤后,脂肪酸合成酶的乙酰化作用调节小胶质细胞脂滴的积累和促炎活性。

Hepatic Aquaporin 8 Promotes Alcohol Consumption and Ameliorates Alcohol-Induced Liver Injury by Facilitating Acetaldehyde Excretion.

肝脏水通道蛋白 8 通过促进乙醛排泄来促进酒精摄入并减轻酒精引起的肝损伤。

Chen Cheng, Lin Yu-Hong, Feng Dechun, Guan Yukun, Fu Yaojie, Wang Yang, Maccioni Luca, Seyhan Deniz, Yao Tiantian, Wei Shoupeng, Zhang Li, Kunos George, Mackowiak Bryan, Gao Bin

MYLK4 promotes colorectal cancer progression by regulating lipid metabolism reprogramming via targeting ferroptosis.

MYLK4 通过靶向铁死亡来调节脂质代谢重编程,从而促进结直肠癌的进展。

Deficiency of glycogen synthase promotes lipid accumulation through ChREBP and AKT-mTOR1-SREBP1 axis activation in mice.

糖原合成酶缺乏通过激活 ChREBP 和 AKT-mTOR1-SREBP1 轴促进小鼠体内脂质积累。

Li Liangkui, Lang Jianan, Yang Longyan, Zhao Dong

β-Sitosterol enhances the anti-tumor efficacy of sorafenib in hepatocellular carcinoma via the FXR/LXR/ SREBP1/ FASN pathway.

β-谷甾醇通过 FXR/LXR/SREBP1/FASN 通路增强索拉非尼对肝细胞癌的抗肿瘤疗效。

Yan Aiwen, Huang Zihan, Kong Liang, Cheng Zhaoyan, Song Yuewen, Li Xiaomao, Jiang Pan, Yan Yuhui

Differential expression and prognostic role of ACACA, ACLY, and FASN in schistosomiasis-associated versus hepatitis B virus-related liver cancer.

ACACA、ACLY 和 FASN 在血吸虫病相关肝癌与乙型肝炎病毒相关肝癌中的差异表达及其预后作用。

Wang Xiao-Yi, Sun Yi-Hui, Wu Qiong-Le, Liang Man-Man, Wang Zi-Jian, Hao Yao, Pan Zhi-Yu, Xu Xiu-Liang, Yang Jiang-Hua

The crucial function of IDO1 in pulmonary fibrosis: From the perspective of mitochondrial fusion in lung fibroblasts and targeted molecular inhibition.

IDO1 在肺纤维化中的关键作用:从肺成纤维细胞线粒体融合和靶向分子抑制的角度

Wang Lei, Ge Shanchun, Zhang Ye, Feng Deqin, Zhu Ting, Zhang Louqian, Zhang Chaofeng

Endothelial SIRT3 deficiency predisposes brown adipose tissue to whitening in diet-induced obesity.

内皮细胞 SIRT3 缺乏会使棕色脂肪组织在饮食引起的肥胖中更容易变白

Zhou Qing, Lu Zongshi, Wang Bowen, Wang Yuyan, Li Li, You Mei, Wang Lijuan, Cao Tingbing, Tong Dan, Xiang Jie, Zhao Yu, Li Qiang, Mou Aidi, Shu Wentao, He Hongbo, Zhao Zhigang, Liu Daoyan, Zhu Zhiming, Gao Peng, Yan Zhencheng

SREBF1 mediates immunoparalysis of dendritic cells in sepsis by regulating lipid metabolism and endoplasmic reticulum stress.

SREBF1 通过调节脂质代谢和内质网应激介导脓毒症中树突状细胞的免疫麻痹

Zhang Yaolu, Wu Fangfang, Li Yan, Liu Jiaxin, Zhu Liuyan, Zhang Min, Lu Zhongqiu

Exosomal miR-375-3p mediated lipid metabolism, ferritinophagy and CoQ-dependent pathway contributes to the ferroptosis of keratinocyte in SJS/TEN

外泌体 miR-375-3p 介导的脂质代谢、铁蛋白吞噬和 CoQ 依赖性途径导致 SJS/TEN 角质形成细胞铁死亡

Chen Zhang, Pei Qiao, ChunYing Xiao, ZiPeng Cao, JiaoLing Chen, Hui Fang, JianKang Yang, ZeHua Kang, ErLe Dang, Shuai Shao, BingYu Pang, QingYang Li, ZhenLai Zhu, ShengXian Shen, Akito Hasegawa, Riichiro Abe, HongJiang Qiao, Gang Wang, Meng Fu
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