Anti-Fibronectin antibody [EPR23110-46] (Ab268020)
FN, FN1, Fibronectin, Cold-insoluble globulin, CIG
用户验证的应用
推荐稀释比例
- IHC-P1/2000 Perform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
- WB1/1000 This product is not suitable for testing mouse and rat tissue samples in western blot.
- ICC/IF1/50
- IHC-Fr1/500 Heat mediated antigen retrieval using sodium citrate buffer (10mM citrate pH 6.0 + 0.05% Tween-20).
详细信息
背景信息
Anti-Fibronectin antibody [EPR23110-46] (ab268020) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-Fr, IHC-P, WB in human, mouse, rat samples. Anti-Fibronectin antibody [EPR23110-46] (ab268020) has been cited over 46 times in peer reviewed journals and is trusted by the scientific community. Abcams high quality manufacturing and validation processes ensure Anti-Fibronectin antibody [EPR23110-46] (ab268020) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Fibronectin antibody [EPR23110-46] (ab268020) has been confirmed by testing in knockout samples. Anti-Fibronectin antibody [EPR23110-46] (ab268020) specifically detects Fibronectin (UniProt ID: P02751; Molecular weight: 269kDa) and is sold in 100 uL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR23110-46 - ab26822. Antibody clone EPR23110-46 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 594, Alexa Fluor® 568, Alexa Fluor® 555, Alexa Fluor® 647, Alexa Fluor® 488, Alexa Fluor® 75 ( ab3964, ab3132, ab313223, ab31335, ab314679, ab321527 ). Fibronectin is a crucial extracellular matrix protein that significantly influences tumor development and progression by enhancing tumor growth, metastasis, and angiogenesis. It interacts with integrin receptors to help tumor cells adapt and survive in harsh microenvironments. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (140)
Apolipoprotein E knockout attenuates vascular graft fibrosis by reducing profibrotic macrophage formation through low-density lipoprotein receptor related protein 1.
载脂蛋白 E 敲除通过低密度脂蛋白受体相关蛋白 1 减少促纤维化巨噬细胞的形成,从而减轻血管移植纤维化。
Extracellular Vesicles Coordinate Bacterial Cloaking in Lung Epithelial Cells to Alleviate Acute Inflammatory Injury.
细胞外囊泡协调肺上皮细胞中的细菌隐蔽作用,以减轻急性炎症损伤。
NCOA4-Mediated Ferritinophagy Induces Ferroptosis and Enriches Ferritin-Containing EVs via Ferritin Phase Separation to Promote Mechanical Ventilation-Induced Pulmonary Fibrosis.
NCOA4 介导的铁蛋白自噬诱导铁死亡,并通过铁蛋白相分离富集含铁蛋白的细胞外囊泡,从而促进机械通气诱导的肺纤维化。
A facile polysaccharide hydrogel activates PPARγ via the Gut-Kidney axis to ameliorate chronic kidney disease.
一种简便的多糖水凝胶通过肠-肾轴激活PPARγ,从而改善慢性肾脏疾病。
Senolytics, dasatanib plus quercetin, reduce kidney inflammation, senescent cell abundance, and injury while restoring geroprotective factors in murine diabetic kidney disease.
衰老细胞清除剂达沙替尼加槲皮素可减少小鼠糖尿病肾病中的肾脏炎症、衰老细胞数量和损伤,同时恢复抗衰老因子。
Decellularized extracellular matrix restores Fibronectin/Integrin β1 balance through extracellular vesicles to rejuvenate chondrocytes and alleviate osteoarthritis progression.
脱细胞细胞外基质通过细胞外囊泡恢复纤连蛋白/整合素β1平衡,从而使软骨细胞恢复活力并缓解骨关节炎的进展。
LXW7 Peptide Modification of Acellular Liver Scaffolds Improves Endothelialization and Hemocompatibility in Bioengineered Liver.
LXW7肽修饰无细胞肝脏支架可改善生物工程肝脏的内皮化和血液相容性。
BMPR2 affects valve development via ECM-receptor interaction in zebrafish.
BMPR2 通过 ECM-受体相互作用影响斑马鱼的瓣膜发育。
A rat model of Immunologic and hypertensive kidney injury.
免疫性和高血压性肾损伤的大鼠模型。
G-CSF promotes H3K27ac-modified KLF5 to activate CXCR4 expression and drive colon cancer growth and metastasis.
G-CSF 促进 H3K27ac 修饰的 KLF5 激活 CXCR4 表达,从而驱动结肠癌的生长和转移。
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