Anti-CD11b antibody [EPR1344] (Ab133357)
CD11b, CD11B, CR3A, ITGAM, Integrin alpha-M, CD11 antigen-like family member B, CR-3 alpha chain, Cell surface glycoprotein MAC-1 subunit alpha, Leukocyte adhesion receptor MO1, Neutrophil adherence receptor
详细信息
背景信息
Anti-CD11b antibody [EPR1344] (ab133357) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in IHC-P, WB and mIHC. Anti-CD11b antibody [EPR1344] (ab133357) was first used in a scientific publication in 1976 and has been cited over 347 times in peer reviewed journals. It's performance in IHC in mouse and human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD11b antibody [EPR1344] (ab133357) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD11b antibody [EPR1344] (ab133357) has 31 independent reviews from customers. Anti-CD11b antibody [EPR1344] (ab133357) specifically detects CD11b (UniProt ID: P11215; Molecular weight: 126kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR1344 - ab209970. Antibody clone EPR1344 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor ® 488, Alexa Fluor ® 555, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 568, Alexa Fluor ® 750, Biotin ( ab204472, ab307387, ab307391, ab307523, ab311811, ab313094, ab321047, ab322298 ). CD11b is involved in various diseases by regulating immune cell adhesion, migration and activation, which can influence inflammation, autoimmune conditions and cancer progression. Multiplex IHC staining using Opal in mouse spleen tissue Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (512)
Spatial heterogeneity of MDSCs mediated by ANXA1-FPRs signaling drives immune suppression in OSCC progression.
MDSC 的空间异质性由 ANXA1-FPR 信号介导，驱动 OSCC 进展中的免疫抑制。
Mycobacterium tuberculosis modulates phosphorylation of host ATP6V1E1 to promote intracellular survival.
结核分枝杆菌通过调节宿主 ATP6V1E1 的磷酸化来促进其在细胞内的生存。
Tissue-resident macrophage survival depends on mitochondrial function regulated by SerpinB2 in chronic inflammation.
组织驻留巨噬细胞的存活依赖于线粒体功能，而线粒体功能在慢性炎症中受 SerpinB2 调控。
Magnetoelectric nanoparticles drive TAF9B(+) T(H)2 cell expansion to alleviate inflammation.
磁电纳米粒子驱动 TAF9B(+) T(H)2 细胞扩增以减轻炎症。
PAD4 promotes macrophage migration to aggravate tubulointerstitial injury in diabetic kidney disease.
PAD4促进巨噬细胞迁移，加重糖尿病肾病中的肾小管间质损伤。
Tandem Duplications in UBTF Create XPO1-Dependent Nuclear Export Signals that Reveal a Leukemic Therapeutic Dependency.
UBTF 中的串联重复产生 XPO1 依赖性核输出信号，揭示白血病治疗依赖性。
Comprehensive single-cell metabolic profiling identifies targets to sensitize triple-negative breast cancer to chemo-immunotherapy.
全面的单细胞代谢谱分析确定了可增强三阴性乳腺癌对化疗免疫疗法敏感性的靶点。
Increased IL4I1 expression predicts poor survival and modulates the immune microenvironment in acute myeloid leukemia.
IL4I1 表达增加预示着生存率低，并调节急性髓系白血病的免疫微环境。
Liver Sinusoidal Endothelial Cells Promote Metabolic Dysfunction-associated Steatohepatitis Progression via Interleukin-1R1-mediated Chemokine Production Induced by Macrophage-derived Interleukin-1β.
肝窦内皮细胞通过巨噬细胞衍生的白细胞介素-1β诱导的白细胞介素-1R1介导的趋化因子产生，促进代谢功能障碍相关的脂肪性肝炎进展。
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