Anti-Cyclin D1 antibody [EPR2241] - C-terminal (Ab134175)
BCL1, PRAD1, CCND1, G1/S-specific cyclin-D1, B-cell lymphoma 1 protein, BCL-1 oncogene, PRAD1 oncogene, BCL-1
详细信息
特异性
The immunogen used for this product shares 66% homology with CCND2 (seven amino acid stretch with 100% homology). Based on internal testing in WB, this product shows a weak cross-reactivity to Cyclin D2. For IHC usage, this product shows a tissue localization specific to Cyclin D1 with no cross-reactivity to Cyclin D2.
背景信息
Product Specifications Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P, IP, WB in human, mouse, rat samples. Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) specifically detects Cyclin D1 (UniProt ID: P24385; Molecular weight: 34kDa) and is sold in 50 µL, 100 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality manufacturing and validation processes ensure Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) has been confirmed by testing in knockout samples. Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) has been cited over 783 times in peer reviewed journals and is trusted by the scientific community. Anti-Cyclin D1 antibody [EPR2241] - C-terminal (ab134175) has 15 independent reviews from customers. Related Products Antibody clone EPR2241 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor® 488, Alexa Fluor® 647, HRP, Alexa Fluor® 594, Alexa Fluor® 555 ( ab190194, ab190563, ab190564, ab203446, ab203448 ). Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (710)
Selenomethionine alleviates aortic dissection via PGC-1α/NRF2/TFAM-mediated mitochondrial biosynthesis against ferroptosis: an experimental study.
硒代蛋氨酸通过 PGC-1α/NRF2/TFAM 介导的线粒体生物合成对抗铁死亡来缓解主动脉夹层：一项实验研究。
Danggui-Baishao herb pair protects against dextran sulfate sodium-induced colitis by modulating the Wnt/β-catenin pathway.
当归-白骨药组合通过调节 Wnt/β-catenin 通路来预防葡聚糖硫酸钠诱发的结肠炎。
CBX2 promotes cisplatin resistance in ovarian cancer via SIAH2-mediated β-catenin stabilization and ATG9B-dependent autophagy activation.
CBX2 通过 SIAH2 介导的 β-catenin 稳定和 ATG9B 依赖的自噬激活促进卵巢癌的顺铂耐药性。
DNASE1L3 Mediates Hepatocellular Carcinoma Tumor Growth and Organoid Models via the Wnt/β-Catenin Signaling Pathway.
DNASE1L3 通过 Wnt/β-catenin 信号通路介导肝细胞癌肿瘤生长和类器官模型。
Resveratrol inhibits bladder cancer proliferation by targeting the AURKA/STAT3 axis: From computational analysis to experimental validation.
白藜芦醇通过靶向 AURKA/STAT3 轴抑制膀胱癌增殖：从计算分析到实验验证。
Enhancing human-induced pluripotent stem cell proliferation and cardiac differentiation through 810-nm photobiomodulation.
通过 810 纳米光生物调节增强人类诱导多能干细胞增殖和心脏分化。
BRD4 Induces Esophageal Squamous Cell Carcinoma Progression via the Wnt/β-catenin Pathway
BRD4通过Wnt/β-catenin通路诱导食管鳞状细胞癌进展
Hepatic stellate cells control liver zonation, size and functions via R-spondin 3
肝星状细胞通过R-spondin 3控制肝脏分区、大小和功能。
C-terminal amides mark proteins for degradation via SCF-FBXO31
端酰胺标记蛋白质通过 SCF-FBXO31 降解
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