Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (Ab133615)
Calnexin, IP90, Major histocompatibility complex class I antigen-binding protein p88, p90, CANX
详细信息
特异性
Recognizes ER membrane, mitochondria and cis-Golgi.
背景信息
Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (ab133615) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), IHC-P, WB in human samples. Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (ab133615) has been cited over 78 times in peer reviewed journals and is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (ab133615) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (ab133615) has been confirmed by testing in knockout samples. Anti-Calnexin antibody [EPR3633(2)] - ER Membrane Marker (ab133615) specifically detects Calnexin (UniProt ID: P27824; Molecular weight: 65kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR3633(2) - ab225542. Antibody clone EPR3633(2) is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor® 594, APC, PE, Alexa Fluor® 488, Alexa Fluor® 647, Alexa Fluor® 568, Alexa Fluor® 555 ( ab195198, ab203439, ab310822, ab310899, ab310982, ab311104, ab312999, ab313204 ). References regarding specificity Horner SM et al. Mitochondrial-associated endoplasmic reticulum membranes (MAM) form innate immune synapses and are targeted by hepatitis C virus. Proc Natl Acad Sci U S A 108:14590-5 (2011). PubMed: 21844353 Myhill N et al. The subcellular distribution of calnexin is mediated by PACS-2. Mol Biol Cell 19:2777-88 (2008). PubMed: 18417615 Yoshimura SI et al. Direct targeting of cis-Golgi matrix proteins to the Golgi apparatus. J Cell Sci 114:4105-15 (2001). PubMed: 11739642 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (201)
Cord blood natural killer cell-derived extracellular vesicles inhibit Zika virus infectivity through ITGB2/perforin-mediated envelope disruption in vitro and in vivo.
脐带血自然杀伤细胞衍生的细胞外囊泡通过 ITGB2/穿孔素介导的包膜破坏在体外和体内抑制寨卡病毒的感染性。
Programmable iPSC-derived CAR-NK vesicles remodel the immune microenvironment and eradicate tumors
可编程的iPSC衍生CAR-NK囊泡重塑免疫微环境并根除肿瘤
Extracellular vesicles from TNF-α and TGF-β1-treated ADSCs promote tissue-engineered cartilage regeneration by modulating macrophages via the miR-378a-3p/SIRPα axis.
TNF-α 和 TGF-β1 处理的 ADSC 的细胞外囊泡通过 miR-378a-3p/SIRPα 轴调节巨噬细胞,从而促进组织工程软骨再生。
MSC-Derived Exosomal lnc-AGT-3: A Novel Anti-Angiogenic Target in Age-Related Macular Degeneration Through p53 Signaling Pathway.
MSC衍生的外泌体lnc-AGT-3:通过p53信号通路在年龄相关性黄斑变性中发挥新型抗血管生成作用。
Identification and diagnostic evaluation of an aptamer targeting prostate-cancer-derived small extracellular vesicles.
鉴定和诊断评价靶向前列腺癌衍生的小细胞外囊泡的适体。
MYO1C is a urinary extracellular vesicle biomarker and mediator of podocyte injury in diabetic nephropathy.
MYO1C 是尿液细胞外囊泡生物标志物,也是糖尿病肾病中足细胞损伤的介质。
Comparative Profiling of Mouse and Human Microglial Small Extracellular Vesicles Reveals Conserved Core Functions with Distinct miRNA Signatures.
小鼠和人类小胶质细胞小细胞外囊泡的比较分析揭示了保守的核心功能和独特的 miRNA 特征。
TSG-6 Activated MSC-derived Extracellular Vesicles Present Altered micro-RNA Contents and Ameliorate the Inflammatory Phenotype of Macrophages in Vitro.
TSG-6 激活的 MSC 衍生的细胞外囊泡表现出改变的 microRNA 含量,并改善了体外巨噬细胞的炎症表型。
Nitrogen cavitation enables rapid and high-yield preparation of functional cell-membrane-derived vesicles.
氮气空化技术能够快速、高产地制备功能性细胞膜衍生囊泡。
Adipose extracellular vesicles carrying miR-210-3p drive macrophage inflammation and nicotine-induced atherosclerosis.
携带 miR-210-3p 的脂肪细胞外囊泡驱动巨噬细胞炎症和尼古丁诱导的动脉粥样硬化。
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