Anti-CD4 antibody [EPR6855] (Ab133616)
CD4, T-cell surface glycoprotein CD4, T-cell surface antigen T4/Leu-3
用户验证的应用
推荐稀释比例
- IHC-P1/500 For unpurified use at 1/100 - 1/250. Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
- WB1/5000 For unpurified use at 1/1000 - 1/10000.
- ICC/IF1/100 - 1/250
- Flow Cyt (Intra)1/100 ab172730 - Rabbit monoclonal IgG, is suitable for use as an isotype control with this antibody.
详细信息
背景信息
Anti-CD4 antibody [EPR6855] (ab133616) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-P, WB and mIHC. Anti-CD4 antibody [EPR6855] (ab133616) was first used in a scientific publication in 2014 and has been cited over 318 times in peer reviewed journals. It's performance in IHC and Immunofluorescence in human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-CD4 antibody [EPR6855] (ab133616) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-CD4 antibody [EPR6855] (ab133616) has 19 independent reviews from customers. Anti-CD4 antibody [EPR6855] (ab133616) specifically detects CD4 (UniProt ID: P01730; Molecular weight: 49kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR6855 - ab181724. Antibody clone EPR6855 is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor ® 647, Alexa Fluor ® 488, Alexa Fluor ® 594, Alexa Fluor ® 555 ( ab195842, ab196147, ab196372, ab277931, ab280849 ). IL-4 plays a role in conditions like systemic lupus erythematosus (SLE) and multiple sclerosis, where it influences immune responses and inflammation. Specificity and sensitivity confirmed in IHC with multi-tissue microarray (TMA) validation Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (530)
Linavonkibart and pembrolizumab in immune checkpoint blockade-resistant advanced solid tumors: a phase 1 trial.
Linavonkibart 和 pembrolizumab 治疗免疫检查点阻断耐药的晚期实体瘤:一项 1 期试验。
IGSF11-VISTA is a critical and targetable immune checkpoint axis in diffuse midline glioma.
IGSF11-VISTA 是弥漫性中线胶质瘤中一个关键且可靶向的免疫检查点轴。
A pan-cancer single cell landscape reveals heterogeneity and functional diversity of double-negative T cells.
泛癌单细胞图谱揭示了双阴性 T 细胞的异质性和功能多样性。
Identification of altered immune landscape at single-cell resolution in NSCLC brain metastasis and its association with poor immune checkpoint inhibitor responses.
在单细胞分辨率下识别非小细胞肺癌脑转移中改变的免疫景观及其与免疫检查点抑制剂反应不良的关系。
A proteogenomic atlas of 1032 brain metastases identifies molecular subtypes, immune landscapes, and therapeutic vulnerabilities.
对 1032 例脑转移瘤进行蛋白质基因组图谱分析,确定了分子亚型、免疫图谱和治疗脆弱性。
Mutant KRAS vaccine with dual checkpoint blockade in resected pancreatic cancer: a phase I trial.
突变型 KRAS 疫苗联合双重检查点阻断治疗切除的胰腺癌:一项 I 期试验。
Circadian fluctuation of soluble CD26 dictates the impact of the timing of cord blood transplantation on acute graft-versus-host disease.
可溶性 CD26 的昼夜节律波动决定了脐带血移植时机对急性移植物抗宿主病的影响。
A Lung-Immune Dual-Humanized Mouse Using Cryopreserved Tissue Enables Infection and Immune Profiling of Human Common Cold Coronaviruses.
利用冷冻保存的组织构建的肺部免疫双重人源化小鼠能够感染人类普通感冒冠状病毒并进行免疫分析。
Integrative Multi-Omics Analysis Uncovers Immunological Phenotypes Predictive of Combinatorial Immunotherapy Response in Gastric Cancer.
整合多组学分析揭示了预测胃癌联合免疫疗法反应的免疫表型。
Retinoic Acid Reprograms Mast Cells Toward a Proinflammatory State to Enhance Antitumor Immunity.
维甲酸将肥大细胞重编程为促炎状态,从而增强抗肿瘤免疫力。
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