Anti-mTOR antibody [EPR390(N)] (Ab134903)

FRAP, FRAP1, FRAP2, RAFT1, RAPT1, MTOR, Serine/threonine-protein kinase mTOR, FK506-binding protein 12-rapamycin complex-associated protein 1, FKBP12-rapamycin complex-associated protein, Mammalian target of rapamycin, Mechanistic target of rapamycin, Rapamycin and FKBP12 target 1, Rapamycin target protein 1, Tyrosine-protein kinase mTOR, mTOR

反应种属:Human, Mouse, Rat
抗原名称:mTOR
应用:WB, IHC

用户验证的应用

推荐稀释比例

  • IHC-PPerform heat-mediated antigen retrieval with Tris/EDTA buffer pH 9.0 before commencing with IHC staining protocol.
  • WB1/10000

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-mTOR antibody [EPR390(N)]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Stable for 12 months at -20°C
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-mTOR antibody [EPR390(N)] (ab134903) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P) in Human, Mouse, Rat samples. What is the molecular weight of mTOR? Anti-mTOR [EPR390(N)] (ab134903) specifically detects a band for mTOR (UniProt: P42345) at a molecular weight of 289kDa. Trusted by the scientific community Anti-mTOR [EPR390(N)] (ab134903) was first used in a scientific publication in 2012 and has been cited over 120 times in peer-reviewed journals. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Specificity confirmed The specificity of Anti-mTOR antibody [EPR390(N)] (ab134903) has been confirmed by Western blot testing in MTOR Knockout HEK293T cells. Other related products We have a range of other formats of antibody clone [EPR390(N)] also available for your convenience: ab134903, Carrier free - ab248718 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (233)

Targeted inhibition of RGS19 alleviates renal fibrosis by restoring autophagy and modulating immune cell infiltration.

靶向抑制 RGS19 可通过恢复自噬和调节免疫细胞浸润来缓解肾纤维化。

Niu Xinhao, Zhao Yufeng, Li Long, Xu Xiaoqing, Xu Cuidi, Wu Jiaheng, Yu Xiaohan, Chen Yanbo, Rong Ruiming, Xu Bin

Bacteriocin-transport-inspired oral peptide-probiotic delivery ameliorates IBD complications via autophagy and gut homeostasis.

受细菌素运输启发的口服肽益生菌递送通过自噬和肠道稳态改善 IBD 并发症。

Yu Yang, Bu Yuting, Shen Chao, Lin Bingru, Lu Chao, Zhu Lin, Shen Zhe, Li Chong, Li Xin

INHBA, regulated by C/EBPβ, induces M2 macrophage polarization to promote tumor metastasis and growth via activating the PI3K/AKT pathway in gastric cancer.

INHBA 受 C/EBPβ 调控,诱导 M2 巨噬细胞极化,通过激活胃癌中的 PI3K/AKT 通路促进肿瘤转移和生长。

Shi Duan-Bo, Qin Yong-Chao, Liu Sen, Zhao Rui-Nan, He Jun-Yi, Ma Ran-Ran, Gao Peng

FGFR2 is a Candidate Immune-Associated Marker of Diabetic Foot Ulcer That Promotes Keratinocyte Function by Activating the PI3K/Akt and MAPK Pathways.

FGFR2 是糖尿病足溃疡的候选免疫相关标志物,它通过激活 PI3K/Akt 和 MAPK 通路促进角质形成细胞功能。

Chen Hailan, Sang Hongfei, Shi Yi, Pan Jie, Zhang Chuang, Lei Fengrui

Cycloastragenol Inhibits Colorectal Cancer Cell Metastasis via Epithelial-Mesenchymal Transition and the PI3K Signalling Pathway.

环阿斯特拉醇通过上皮-间质转化和PI3K信号通路抑制结直肠癌细胞转移。

Miao JingRong, Feng PanFeng

Mechanisms of hesperetin in alleviating diabetic nephropathy: Network pharmacology, molecular docking, and experimental validation.

橙皮苷缓解糖尿病肾病的机制:网络药理学、分子对接和实验验证。

Guo Yiwen, Zhang Fengjiao, Jin Yu, Zhu Menglu, Kang Zhiqiang

Intervention of Rutin and Ochnaflavone in the Attenuation of Neuroinflammation and Neuronal Apoptosis in Spinal Cord Injury.

芦丁和金盏花酮在脊髓损伤中减轻神经炎症和神经元凋亡的作用。

Yu Tao, Yang Xuhao, Dai Anyuan, Yun Zhihe, Xue Wu, Yuan Tianyang, Nie Xinyu, Han Inbo, Liu Yanting, Wang A O, Liu Qinyi

Targeting SRSF1 improves cancer immunotherapy by dually acting on CD8+T and tumor cells

靶向SRSF1可通过双重作用于CD8+T细胞和肿瘤细胞来增强癌症免疫疗法。

Gui-Qi Zhu # ,Zheng Tang # ,Tian-Hao Chu # ,Biao Wang # ,Shi-Ping Chen ,Chen-Yang Tao ,Jia-Liang Cai ,Rui Yang ,Wei-Feng Qu ,Yi Wang ,Qian-Fu Zhao ,Run Huang ,Meng-Xin Tian ,Yuan Fang ,Jun Gao ,Xiao-Ling Wu ,Jian Zhou ,Wei-Ren Liu ,Zhi Dai ,Ying-Hong Shi ,Jia Fan

SREBP1-mediated lipogenesis promotes dedifferentiation and senescence of vascular smooth muscle cells through epigenetic remodeling.

SREBP1介导的脂肪生成通过表观遗传重塑促进血管平滑肌细胞的去分化和衰老。

Li Bowen, Zhou Kaixiang, Yin Anan, Liu Yonghong, Wang Xichen, Cui Yujia, Liu Fangfang, Liu Qiurong, Zheng Hongjing, Mu Zhiqiang, Chen Kun, Wu Yuanming, Chang Yaoming, Bao Junxiang

A TEMPO-loaded DNA hydrogel enabling integrated early diagnosis and treatment of osteoarthritis.

载有TEMPO的DNA水凝胶可实现骨关节炎的早期诊断和治疗。

Huang Hong, Tang Mingze, Hu Pengcheng, Zhan Yingshi, Sun Wei, Zheng Weipeng, Zhu Jianwei, Chen Jianmao, Xue Song, Huang Shiqian, Han Weiyu, Zhang Chao, Ding Changhai, Zhang Yan, Li Shushu, Ruan Guangfeng
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 24