Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (Ab137869)

TYH, TH, Tyrosine 3-monooxygenase, Tyrosine 3-hydroxylase

反应种属:Human, Mouse, Rat
抗原名称:TH
应用:WB, IHC, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

背景信息

Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (ab137869) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-P and WB. Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (ab137869) was first used in a scientific publication in 2016 and has been cited over 69 times in peer reviewed journals. It's performance in Western Blot in mouse samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (ab137869) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (ab137869) has 9 independent reviews from customers. Anti-Tyrosine Hydroxylase antibody [EP1532Y] - Neuronal Marker (ab137869) specifically detects Tyrosine Hydroxylase (UniProt ID: P07101; Molecular weight: 59kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EP1532Y - ab220218. Antibody clone EP1532Y is also available pre-conjugated to a variety of labels for your convenience - HRP, Alexa Fluor ® 488, Alexa Fluor ® 568, Alexa Fluor ® 555, APC, PE, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 750 ( ab207673, ab302827, ab302968, ab305365, ab310825, ab310901, ab311092, ab311693, ab321111 ). NEW: Explore our alternative host species for clone EP1532Y: goat, mouse, chicken. Tyrosine hydroxylase (TH) is a critical enzyme in neuro research, particularly for its role in the synthesis of catecholamines, including dopamine, norepinephrine and epinephrine. It is a key marker for identifying dopaminergic neurons in the central nervous system. Researchers use tyrosine hydroxylase to study the regulation of neurotransmitter production and its implications in neurological disorders such as Parkinson's disease (PD) and tyrosine hydroxylase deficiency. Its expression helps in understanding the biochemical pathways involved in neurodegenerative diseases and the development of potential therapeutic strategies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (163)

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Upregulated GBP2 exacerbates Parkinson's disease pathogenesis by impairing NIX-dependent mitophagy.

GBP2 上调会损害 NIX 依赖性线粒体自噬,从而加剧帕金森病的发病机制。

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Multi-omic insight into the molecular mechanism of cuproptosis-related genes in the pathogenesis of Parkinson's disease.

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Transcranial direct current stimulation exerts neuroprotective effects in Parkinson's disease by restoring Mlst8-mediated autophagic homeostasis

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Zekun Tian #,Chao Long #,Juan Wei #,Yan Jiang,Yi Liu,Zhenyu Liu,Manxia Li,Keshu Yang,Chengbiao Ding,Tsung-Hsun Hsieh,Xiaojun Feng

BAP31 Modulates Mitochondrial Homeostasis Through PINK1/Parkin Pathway in MPTP Parkinsonism Mouse Models.

BAP31 通过 PINK1/Parkin 通路调节 MPTP 帕金森病小鼠模型中的线粒体稳态。

Zhang Wanting, Meng Shihao, Hao Zhenzhen, Zhu Xiaoshuang, Cao Lingwei, Yuan Qing, Wang Bing

Sex-specific metabolic and microbial remodeling in a rotenone-induced rat model of Parkinson's disease following nicotine administration.

在尼古丁给药后,鱼藤酮诱导的帕金森病大鼠模型中存在性别特异性的代谢和微生物重塑。

Ni Zhen, Wang Gaoge, Li Qian, Wu Xiaqing, Song Zheng, Yu Hao, Yu Pengpeng, Chen Yibo, Li Lixiang, Chen Huan, Hou Hongwei, Hu Qingyuan

A dopaminergic projection from the ventral tegmental area to the dorsal raphe nucleus critically regulates propofol anesthesia in mice.

从腹侧被盖区到背侧缝核的多巴胺能投射对小鼠的丙泊酚麻醉起着至关重要的调节作用。

He Junjie, Yao Tianxi, Guo Huan, He Haichuan, Tian Zhuangzhuang, Ma Ketao, Yin Jiangwen, Li Yan

Zhigancao decoction alleviates Parkinson's disease via inhibiting TNF/NF-κB and Ras/ERK-mediated neuroinflammation and apoptosis.

炙甘草汤通过抑制 TNF/NF-κB 和 Ras/ERK 介导的神经炎症和细胞凋亡来缓解帕金森病。

Zhang Jiakang, Yu Xinlang, Fang Yuan, Li Wenshan, Cui Qi, Liu Xiaoyu, Jiang Yanjie, Zhang Yin, Xu Chengcheng, Sun Xin, Lu Yan

Transcutaneous Auricular Vagus Nerve Stimulation Alleviates Headache Symptoms in Migraine Model Mice by the Locus Coeruleus/Noradrenergic System: An Experimental Study in a Mouse Model of Migraine.

经皮耳迷走神经刺激通过蓝斑/去甲肾上腺素能系统缓解偏头痛模型小鼠的头痛症状:偏头痛小鼠模型的实验研究。

Song Xingke, Chen Zijie, Zhu Haohan, Rong Peijing, Zhang Jinling, Pu Xue, Wang Junying

Synergistic Effects of Levodopa, Benserazide, and Nortriptyline on Behavioral Impairments and Brain Pathology in an Experimental Rat Model of Parkinson's Disease.

左旋多巴、苄丝肼和去甲替林对帕金森病实验大鼠模型行为障碍和脑病理的协同作用。

Ezzedin Maryam, Zarbakhsh Sam, Parsaei Houman, Ghanbari Ali, Vafaei Abbas Ali, Mohsenvand Zohre, Seyedinia Seyed Ali, Tarahomi Parnia, Safari Manouchehr
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