Anti-Collagen I antibody [EPR7785] (Ab138492)

Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1

反应种属:Human
抗原名称:COL1A1
应用:WB, IHC, IF/ICC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

Compared with ab138492, ab255809 has higher affinity. We recommend ab255809 as an alternative for testing pro-Collagen forms in western blot. ab138492 works in western blot in samples with high level of collagen I, like HFF-1, MRC-5, skin tissue etc. ab138492 is specific for pro-Collagen and 139kda mature from, while ab255809 is specific for pro-Collagen and 35kda C-terminal pro peptide. Please navigate to the Product Protocol section for specificity details in Chinese.

背景信息

Anti-Collagen I antibody [EPR7785] (ab138492) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-Fr IHC-P and WB. Anti-Collagen I antibody [EPR7785] (ab138492) was first used in a scientific publication in 2014 and has been cited over 253 times in peer reviewed journals. It's performance in Western Blot and IHC in human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Collagen I antibody [EPR7785] (ab138492) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Collagen I antibody [EPR7785] (ab138492) has been confirmed by testing in Collagen I knockout cells. Anti-Collagen I antibody [EPR7785] (ab138492) has 34 independent reviews from customers. Anti-Collagen I antibody [EPR7785] (ab138492) specifically detects Collagen I (UniProt ID: P02452; Molecular weight: 95kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR7785 - ab215969. Antibody clone EPR7785 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 568, Alexa Fluor ® 555, Alexa Fluor ® 750 ( ab275996, ab280968, ab311739, ab313018, ab313221, ab321114 ). Collagen I modulates the tumor microenvironment by enhancing tissue rigidity and facilitating neoplastic cell proliferation. Additionally, it contributes to immune evasion by forming a structural barrier that impedes T-cell infiltration and activity. Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

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