Anti-Collagen I antibody [EPR7785] (Ab138492)
Collagen alpha-1(I) chain, Alpha-1 type I collagen, COL1A1
详细信息
特异性
Compared with ab138492, ab255809 has higher affinity. We recommend ab255809 as an alternative for testing pro-Collagen forms in western blot. ab138492 works in western blot in samples with high level of collagen I, like HFF-1, MRC-5, skin tissue etc. ab138492 is specific for pro-Collagen and 139kda mature from, while ab255809 is specific for pro-Collagen and 35kda C-terminal pro peptide. Please navigate to the Product Protocol section for specificity details in Chinese.
背景信息
Anti-Collagen I antibody [EPR7785] (ab138492) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in ICC/IF, IHC-Fr IHC-P and WB. Anti-Collagen I antibody [EPR7785] (ab138492) was first used in a scientific publication in 2014 and has been cited over 253 times in peer reviewed journals. It's performance in Western Blot and IHC in human samples is trusted by the scientific community. Abcam's high quality manufacturing and validation processes ensure Anti-Collagen I antibody [EPR7785] (ab138492) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-Collagen I antibody [EPR7785] (ab138492) has been confirmed by testing in Collagen I knockout cells. Anti-Collagen I antibody [EPR7785] (ab138492) has 34 independent reviews from customers. Anti-Collagen I antibody [EPR7785] (ab138492) specifically detects Collagen I (UniProt ID: P02452; Molecular weight: 95kDa) and is sold in 100 µL and 1 mL selling sizes. Conjugation-ready, carrier free format available for antibody clone EPR7785 - ab215969. Antibody clone EPR7785 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 488, Alexa Fluor ® 647, Alexa Fluor ® 594, Alexa Fluor ® 568, Alexa Fluor ® 555, Alexa Fluor ® 750 ( ab275996, ab280968, ab311739, ab313018, ab313221, ab321114 ). Collagen I modulates the tumor microenvironment by enhancing tissue rigidity and facilitating neoplastic cell proliferation. Additionally, it contributes to immune evasion by forming a structural barrier that impedes T-cell infiltration and activity. Species reactivity Mouse, Rat: We have preliminary internal testing data to indicate this antibody may not react with these species. Please contact us for more information. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.
文献引用 (363)
Integrated biomimetic bioprinting of perichondrium with cartilage for auricle reconstruction
软骨膜与软骨的一体化仿生生物打印用于耳廓重建
Proteomic profiling identifies muscle-invasive bladder cancers with distinct biology and responses to platinum-based chemotherapy
蛋白质组学分析可识别具有独特生物学和对铂类化疗反应的肌肉浸润性膀胱癌
Lgals3 Promotes Calcium Oxalate Crystal Formation and Kidney Injury Through Histone Lactylation-Mediated FGFR4 Activation.
Lgals3 通过组蛋白乳化介导的 FGFR4 激活促进草酸钙晶体形成和肾损伤
Targeting CD13/Aminopeptidase N as a Novel Therapeutic Approach for Scleroderma Fibrosis
以 CD13/氨基肽酶 N 为靶点作为硬皮病纤维化的新治疗方法
Decellularized tissue matrices hydrogels functionalized with extracellular vesicles promote macrophage reprogramming and neural stem cell differentiation for spinal cord injury repair
经细胞外囊泡功能化的脱细胞组织基质水凝胶可促进巨噬细胞重编程和神经干细胞分化,从而修复脊髓损伤。
3D printed porous magnesium metal scaffolds with bioactive coating for bone defect repair: enhancing angiogenesis and osteogenesis
具有生物活性涂层的 3D 打印多孔镁金属支架用于骨缺损修复:增强血管生成和成骨作用
Cationic microbubble loading hSIRT3 and hTIMP3 optimize cardiac-targeted delivery and myocardial protection in the porcine MI/R model.
阳离子微泡负载 hSIRT3 和 hTIMP3 可优化猪 MI/R 模型中的心脏靶向递送和心肌保护
Elastin-like polypeptide and triclosan-modified PCL membrane provides aseptic protection in tissue regeneration.
弹性蛋白样多肽和三氯生修饰的PCL膜在组织再生中提供无菌保护
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