Anti-E Cadherin antibody [4A2] (Ab231303)

CD324, CDHE, UVO, CDH1, Cadherin-1, CAM 120/80, Epithelial cadherin, Uvomorulin, E-cadherin

反应种属:Human, Mouse, Rat
抗原名称:Cdh1
应用:WB, IHC, IF/ICC

用户验证的应用

推荐稀释比例

  • IHC-P1 µg/mL Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
  • WB1 µg/mL Abcam recommends using a 5% milk blocking solution for this antibody.
  • ICC/IF1 µg/mL

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
全称Anti-E Cadherin antibody [4A2]
产品形式Liquid
储存缓冲液Preservative: 0.02% Sodium azide Constituents: PBS
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification

背景信息

Product Specifications Anti-E Cadherin antibody [4A2] (ab231303) is a mouse monoclonal antibody and is validated for use in ICC/IF, IHC-P, WB in human, mouse, rat samples. Anti-E Cadherin antibody [4A2] (ab231303) specifically detects E Cadherin (UniProt ID: P12830; Molecular weight: 80kDa) and is sold in 100 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-E Cadherin antibody [4A2] (ab231303) has high sensitivity and specificity. The specificity of Anti-E Cadherin antibody [4A2] (ab231303) has been confirmed by testing in knockout samples. Anti-E Cadherin antibody [4A2] (ab231303) has been cited over 140 times in peer reviewed journals and is trusted by the scientific community. Related Products Conjugation-ready, carrier free format available for antibody clone 4A2 - ab233766. Want a custom formulation? This antibody clone is manufactured by Abcam. If you require a custom buffer formulation or conjugation for your experiments, please contact orders@abcam.com

文献引用 (316)

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METTL3 介导的 CACNA1E 的 m(6)A 修饰通过增强 WNT7B 介导的 Ca(2+) 信号传导促进骨肉瘤进展和化疗耐药性。

Chen Chaotao, Xiong Kai, Liang Feiyuan, Zhong Yanping, Qin Xiong, Huang Nanchang, Fang Yuqi, Zhu Bo, Cheng Jianwen, Wei Qingjun, Zheng Li, Zhao Jinmin

Targeted inhibition of RGS19 alleviates renal fibrosis by restoring autophagy and modulating immune cell infiltration.

靶向抑制 RGS19 可通过恢复自噬和调节免疫细胞浸润来缓解肾纤维化。

Niu Xinhao, Zhao Yufeng, Li Long, Xu Xiaoqing, Xu Cuidi, Wu Jiaheng, Yu Xiaohan, Chen Yanbo, Rong Ruiming, Xu Bin

Loss-of-function variants in ODAD1 disrupt ODA docking and induce actin cytoskeletal remodeling in primary ciliary dyskinesia.

ODAD1 功能丧失变异会破坏 ODA 停靠,并诱导原发性纤毛运动障碍中的肌动蛋白细胞骨架重塑。

Huo Chunxiao, Luo Ting, Yang Shuo, Jiang Yuan, Guo Mengzhe, Yang Feng, Xu Zhangqi, Xia Junhua, Wu Lei, Xu Weize, Gui Miao, Zhou Tianhua, Xie Shanshan

4D fabrication of scaffolds facilitates the construction of cholangiocyte monolayers from human and mouse liver derived organoids.

4D支架制造有助于利用人和小鼠肝脏来源的类器官构建胆管细胞单层。

Li Junzhi, Chen Shangsi, Chu Jing, Fei Yanghonghong, Chung Patrick Ho-Yu, Wong Kenneth Kak Yuen, Lui Vincent Chi Hang, Tam Paul Kwong Hang

Functional restoration of uterine architecture and fertility via a 3D-printed biomimetic scaffold: The role of macrophage-driven immunomodulation.

通过 3D 打印仿生支架恢复子宫结构和生育能力:巨噬细胞驱动的免疫调节的作用。

Wei Qianqian, Zhang Jing, Weng Jiahao, Lan Jiawen, He Jing, Chen Yuewei, Zou Zhongfei, He Yong, Wang Yanpeng, Shu Jing

APC loss promotes endometrial cancer progression by upregulating FGF12 expression: An integrated multi-omics analysis.

APC 缺失通过上调 FGF12 表达促进子宫内膜癌进展:一项综合多组学分析。

Song Yunfeng, Zhong Cheng, Huang Jian, Shuai Wen, Hu Xiang, Bian Yiding, He Qizhi, Li Yiran

IFFO1 inhibits breast cancer by coordinating mitochondrial fission and fatty acid synthesis via the LaminA/C-PGC1α axis.

IFFO1 通过 LaminA/C-PGC1α 轴协调线粒体分裂和脂肪酸合成,从而抑制乳腺癌。

Cai Huaxia, He Jianjun

The CDO1-ACSM3 Axis Mediates Renal Tubule Lipid Deposition and Injury by Causing Mitochondrial Dysfunction in Lupus Nephritis.

CDO1-ACSM3轴通过引起狼疮性肾炎中的线粒体功能障碍介导肾小管脂质沉积和损伤。

Zhang Zibo, Liu Jinxi, Liu Yunhe, Wang Liwei, Li Zekun, Dong Yan, Tian Yuexin, Miao Xinyan, Liu Qingjuan, Zhang Wei, Guo Huifang, Xing Lingling, Yang Lin, Feng Xiaojuan, Liu Shuxia

Small Intestine-Targeted Long-Acting Oral Insulin Formulation Based on Engineered Milk Protein Nanoparticles.

基于工程化乳蛋白纳米颗粒的小肠靶向长效口服胰岛素制剂。

Thamizhchelvan Anbu Mozhi, Li Yuancheng, Padelford Jonathan, Yang Ce, Yang Chunhua, He Peijian, Galhena Ashan, Wu Tianhe, Lipowska Malgorzata, Mao Hui

Selective inhibition of ALDH1A3 impedes breast cancer growth and metastasis by blocking ALDH1A3-driven transcriptional programs.

选择性抑制ALDH1A3可通过阻断ALDH1A3驱动的转录程序来抑制乳腺癌的生长和转移。

MacLean Maya R, Bernardoni Bianca Laura, Fernando Wasundara, Petrarolo Giovanni, D'Agostino Ilaria, Dean Cheryl A, Venkatesh Jaganathan, Hughes Christopher S, Goralski Kerry B, Subramanian Geetha, Arun Raj Pranap, Cahill Hannah F, Walker Olivia L, Thomas Lynn N, Douglas Robert C, La Motta Concettina, Marcato Paola
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