Anti-CD31 antibody [RM1006] (Ab281583)
CD31, Platelet endothelial cell adhesion molecule, PECAM-1, EndoCAM, GPIIA', PECA1, PECAM1
详细信息
特异性
Internal QC has shown that this product exhibits non‑specific staining in rat kidney tissues by IHC‑P.
背景信息
Product Specifications Anti-CD31 antibody [RM1006] (ab281583) is a recombinant rabbit multiclonal antibody which is comprised of multiple monoclonal antibodies targeting different epitopes and recapitulating the performance of a polyclonal. Each component clone was developed by Abcam using patented rabbit monoclonal antibody technology. Anti-CD31 antibody [RM1006] (ab281583) is validated for use in IHC-P, IP and WB in human, mouse and rat samples. Anti-CD31 antibody [RM1006] (ab281583) specifically detects CD31 (UniProt ID: P16284; Molecular weight: 82kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcams high quality manufacturing and validation processes ensure Anti-CD31 antibody [RM1006] (ab281583) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. Related Products Conjugation-ready, carrier free format available for antibody clone RM1006 - ab282746. Target Information CD31 (PECAM-1) is a protein expressed on endothelial and immune cells, playing a crucial role in tumor angiogenesis and immune cell trafficking. In immuno-oncology, it influences the tumor microenvironment and modulates the immune response to cancer. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents.
文献引用 (162)
TLR2-PI3K/Akt mediated microbe-mimetic priming boosts the therapeutic paracrine function of GelMA-Encapsulated MSCs for diabetic wound regeneration.
TLR2-PI3K/Akt 介导的微生物模拟启动增强了 GelMA 封装的 MSC 的治疗性旁分泌功能，用于糖尿病伤口再生。
Targeting NRP1 in Endothelial Cells Facilitates the Normalization of Scar Vessels and Prevents Fibrotic Scarring.
靶向内皮细胞中的 NRP1 可促进瘢痕血管正常化并防止纤维化瘢痕形成。
A DNA Tetrahedron Delivery Asiatic Acid to Reprogram Mitochondrial Metabolism for Promoting Bone Regeneration via STAT3 Phosphorylation.
通过 STAT3 磷酸化重编程线粒体代谢以促进骨骼再生的 DNA 四面体递送积雪草酸。
Cancer Stem Cells Shift Metabolite Acetyl-Coenzyme A to Abrogate the Differentiation of CD103(+) T Cells.
癌症干细胞转移代谢物乙酰辅酶A以消除CD103(+) T细胞的分化。
Aquaporin 4 and its isoforms regulation ameliorate AQP4 Mis-localization-induced glymphatic dysfunction in ischemic stroke.
水通道蛋白 4 及其亚型的调节可改善缺血性中风中 AQP4 定位错误引起的淋巴功能障碍。
COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.
COPD气道上皮细胞衍生的细胞外囊泡通过miR-141-3p/PDCD4轴促进内皮功能障碍和动脉粥样硬化。
Mitochondrial protein-enriched artificial nanovesicles: mitochondrial recovery and antioxidation for diabetic wound treatment.
富含线粒体蛋白的人工纳米囊泡：用于糖尿病伤口治疗的线粒体恢复和抗氧化作用。
CD146+ pericyte-like lung cancer brain metastatic stem cells promote tumor angiogenesis through dual regulatory effects on the VEGF/VEGFR axis
CD146+周细胞样肺癌脑转移干细胞通过对VEGF/VEGFR轴的双重调控作用促进肿瘤血管生成。
Targeting Macrophage-to-Myofibroblast Transition Mitigates Progression from Inflammation to Fibrosis in Rosacea.
靶向巨噬细胞向肌成纤维细胞的转变可减轻玫瑰痤疮从炎症到纤维化的进展。
Sema3d(hi) Fibroblasts Promote Acute Kidney Injury Fibrotic Progression Through Confining Endothelial Cell Migration.
Sema3d(hi)成纤维细胞通过限制内皮细胞迁移促进急性肾损伤纤维化进展。
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