Anti-OPA1 antibody [EPR11057(B)] (Ab157457)

KIAA0567, OPA1, Optic atrophy protein 1

反应种属:Human, Mouse, Rat
抗原名称:OPA1
应用:WB, IHC

用户验证的应用

推荐稀释比例

  • IHC-P1/250 - 1/500 Perform heat-mediated antigen retrieval before commencing with IHC staining protocol.
  • WB1/1000 - 1/5000
  • IHC-Fr1/250 Heat mediated antigen retrieval using sodium citrate buffer (10mM citrate pH 6.0 + 0.05% Tween-20)

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
全称Anti-OPA1 antibody [EPR11057(B)]
产品形式Liquid
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 50% Tissue culture supernatant, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C
纯化方式Affinity purification Protein A

背景信息

What is this antibody validated in? Anti-OPA1 antibody [EPR11057(B)] (ab157457) is a rabbit recombinant monoclonal antibody and is validated for use in Western Blot (WB), Immunohistochemistry (IHC-P), Immunohistochemistry (IHC-Fr) in Human, Mouse, Rat samples. What is the molecular weight of OPA1? Anti-OPA1 [EPR11057(B)] (ab157457) specifically detects a band for OPA1 (UniProt: O60313) at a molecular weight of 112kDa. Trusted by the scientific community Anti-OPA1 [EPR11057(B)] (ab157457) was first used in a scientific publication in 2013 and has been cited over 60 times in peer-reviewed journals. Reviewed by scientists Anti-OPA1 [EPR11057(B)] (ab157457) has over 5 independent reviews from customers. Trial sizes available! Test your antibody or perform pre-screening before committing to a larger quantity. Sold in 10µl. Discover our selection of trial-size antibodies. Other related products We have a range of other formats of antibody clone [EPR11057(B)] also available for your convenience: ab157457, Carrier free - ab240143 Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (114)

Schisandrol B protects against lithocholic acid-induced cholestatic liver injury in mice through mitochondrial biogenesis.

五味子醇 B 通过线粒体生物合成保护小鼠免受石胆酸引起的胆汁淤积性肝损伤。

Yang Xiao, Liang Hangfei, Li Xuan, Tian Jianing, Fan Shicheng, Huang Min, Wan Jianbo, Zuo Zhong, Guo Haibiao, Bi Huichang

Heart-Specific and Conditional Deletion of the Immt Gene Reveals Its Role in Regulating Mitochondrial Structure and Total Heart Metabolism.

心脏特异性和条件性 Immt 基因缺失揭示了其在调节线粒体结构和心脏整体代谢中的作用。

Kuwabara Yasuhide, Keezer Caitlin, Lin Suh-Chin J, Rajput Akanksha, Molkentin Jeffery D

FKBP51 disrupts the insulin signaling pathway and impairs mitochondrial bioenergetics in HepG2 cells.

FKBP51 会破坏 HepG2 细胞中的胰岛素信号通路并损害线粒体生物能量学。

Donoso-Barraza Camila, Díaz-Roblero Melissa, Sepúlveda Carlos, Villegas-Bravo Anais, Soto-Alarcón Sandra A, Durán-Castillo Danitza, Castillo Valeska, Bravo-Sagua Roberto, Troncoso Rodrigo

Forsythiaside A inhibits the progression of intrahepatic cholangiocarcinoma partially via suppressing oxidative stress-induced hepatic stellate cell activation and macrophage polarization.

连翘苷A通过抑制氧化应激诱导的肝星状细胞活化和巨噬细胞极化,部分抑制肝内胆管癌的进展。

Zhang Shiyu, Du Fan, Liao Ye, Zhang Chuyu, Zhang Meixia

Caffeine Sodium Benzoate-Induced Macrophage M1 Polarization Promotes Endothelial Progenitor Cell Dysfunction by Inducing Mitochondrial Dysfunction Via Targeting let-7a-5p/OPA1 Axis.

苯甲酸钠诱导的巨噬细胞M1极化通过靶向let-7a-5p/OPA1轴诱导线粒体功能障碍,从而促进内皮祖细胞功能障碍。

Yu Tianwei, Yuan Yuanyuan, Suo Feiya, Guo Rong, Li Weixin, Wang Xiaofang, Suriguga, Zhao Huiying, Tian Lili, Yang Hao, Yan Quanzhi, Feng Li

The Potential Role of β-Asarone in Calcium Imbalance and Mitochondrial Dysfunction in Melanoma Cells.

β-细辛脑在黑色素瘤细胞钙失衡和线粒体功能障碍中的潜在作用。

Liu Yuze, Tang Wei, Yu Biao, Yang Qinghua, Lai Wenbing

The loss of OPA1 accelerates intervertebral disc degeneration and osteoarthritis in aged mice.

OPA1 的缺失会加速老年小鼠的椎间盘退变和骨关节炎

Madhu Vedavathi, Hernandaz-Meadows Miriam, Coleman Ashley, Sao Kimheak, Inguito Kameron, Haslam Owen, Boneski Paige K, Sesaki Hiromi, Barve Ruteja A, Collins John A, Risbud Makarand V

Boosting energy metabolism and biosynthesis in diverse organisms by a common bacterial salvage lipoylation protein.

一种常见的细菌补救性脂酰化蛋白能够促进多种生物体的能量代谢和生物合成

Yang Runqing, Wang Yingying, Kong Minghua, Hu Zhijuan, Zhang Zhe, Shen Kun, Meng Jiali, Zeng An-Ping

Histone lactylation stimulated upregulation of PSMD14 alleviates neuron PANoptosis through deubiquitinating PKM2 to activate PINK1-mediated mitophagy after traumatic brain injury.

组蛋白乳酸化刺激 PSMD14 上调,通过去泛素化 PKM2 激活 PINK1 介导的线粒体自噬,从而减轻创伤性脑损伤后的神经元凋亡

Xu Lei, Ye Yangfan, Gu Wei, Xu Xiao, Chen Nuo, Zhang Liuchao, Cai Wanzhi, Hu Jingming, Wang Tian, Chao Honglu, Tu Yiming, Ji Jing

Astragaloside IV alleviates septic myocardial injury through DUSP1-Prohibitin 2 mediated mitochondrial quality control and ER-autophagy.

黄芪甲苷 IV 通过 DUSP1-Prohibitin 2 介导的线粒体质量控制和内质网自噬减轻脓毒症心肌损伤。

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