Anti-CD68 antibody [EPR23917-164] (Ab283654)

CD68, Macrosialin, Cd68

反应种属:Mouse, Rat
抗原名称:CD68
应用:WB, IHC, FCM, IF/ICC, MIHC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein A
储存缓冲液pH: 7.2 - 7.4 Preservative: 0.01% Sodium azide Constituents: PBS, 40% Glycerol (glycerin, glycerine), 0.05% BSA
储存条件运输条件: Conditional Ambient 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

Mouse unsuitable for IHC-Fr application

背景信息

Anti-CD68 antibody [EPR23917-164] (ab283654) was developed by Abcam using patented rabbit monoclonal antibody technology and is validated for use in Flow Cyt (Intra), ICC/IF, IHC-Fr, IHC-P, mIHC, and WB. Abcam's high quality manufacturing and validation processes ensure Anti-CD68 antibody [EPR23917-164] (ab283654) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of Anti-CD68 antibody [EPR23917-164] (ab283654) has been confirmed by Western Blot testing in CD68 knockout RAW 264.7 cells (cell lysate ab280106 ). Anti-CD68 antibody [EPR23917-164] (ab283654) specifically detects CD68 (UniProt ID: P31996; Molecular weight: 33kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Conjugation-ready, carrier free format available for antibody clone EPR23917-164 - ab283667. Antibody clone EPR23917-164 is also available pre-conjugated to a variety of labels for your convenience - Alexa Fluor ® 647, Alexa Fluor ® 594, APC, Alexa Fluor ® 488 ( ab305214, ab312903, ab317758, ab319086 ). CD68 levels is implicated in autoimmune conditions like rheumatoid arthritis, where macrophages contribute to joint inflammation and damage. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents. What are the advantages of a recombinant monoclonal antibody? This product is a recombinant monoclonal antibody, which offers several advantages including - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production For more information, read more on recombinant antibodies.

文献引用 (229)

Hemodynamics-driven magnetoelastic vascular grafts for stenosis diagnosis.

用于狭窄诊断的血流动力学驱动磁弹性血管移植物。

Chen Guorui, Chung Tzuchun, Liu Zeyang, Li Yan-Ruide, Scott Kamryn, Zhao Xun, Carol Jarod, Park Soomin, Zhou Yihao, Kim Wi Jin, Ge Xinyang, Colby Geoffrey P, Li Song, Chen Jun

A dual-functional engineered exosome-laden hydrogel redirects endogenous neural stem cell fate for spinal cord injury repair.

一种双功能工程化外泌体负载水凝胶可改变内源性神经干细胞的命运,用于脊髓损伤修复。

Li Wenxiang, Zhang Wencan, Zheng Han, Zhang Yang, Feng Yanbin, Xie Yujia, Liu Xuanrui, Liu Mingshan, Kong Xiaohong, Ran Ning, Feng Shiqing

Reprogramming Lesional Macrophage Homeostasis via Interferon Regulatory Factor 5 Targeted siRNA Nanoimmunotherapy for Atherosclerosis.

通过干扰素调节因子 5 靶向 siRNA 纳米免疫疗法重编程病变巨噬细胞稳态治疗动脉粥样硬化。

He Zhongshan, Luo Yaoyao, Yang Shuping, Shi Haixing, Huang Ya-Chih, Zhou Zhuoming, Liu Shengbin, Zeng Wanqin, Liu Wei-Chieh, Li Yongjiang, Chen Yuting, Qin Duotian, Duan Xing, He Xi, Chen Wei, Song Xiangrong

Hypoxia-driven remodeling of SELENOP(+) macrophages shapes T cell dynamics and promotes ovarian cancer metastasis.

缺氧驱动的 SELENOP(+) 巨噬细胞重塑塑造 T 细胞动力学并促进卵巢癌转移。

COPD airway epithelial cells-derived extracellular vesicles contribute to endothelial dysfunction and atherosclerosis via the miR-141-3p/PDCD4 axis.

COPD气道上皮细胞衍生的细胞外囊泡通过miR-141-3p/PDCD4轴促进内皮功能障碍和动脉粥样硬化。

Wang Zihan, Shi Jun, Liang Ying, Li Danyang, Luo Ying, Zhang Yue, Chen Yahong, Li Nan, Gai Xiaoyan, Sun Yongchang

Pathology-tailored nanotherapy via Galectin-3-targeted and triple-responsive nanoparticles enables multimodal therapy against aortic dissection.

通过针对 Galectin-3 的三重响应纳米颗粒进行病理定制的纳米疗法,可以实现针对主动脉夹层的多模式治疗。

Lin Chi, Tsai Min-Lang, Chao Hsin-Yi, Cheng Tsai-Mu, Shih Chun-Ming, Wu Alexander T H, Cheng Chia-Hsiung, Hsiao Chen Yuan, Lu Hsin-Ying, Shih Chun-Che, Mi Fwu-Long

Poly-l-lactic acid electrospun membrane with specific morphology promotes bone regeneration through macrophage reprogramming.

具有特定形态的聚左旋乳酸电纺膜通过巨噬细胞重编程促进骨再生。

Tang Daiyuan, Xu Yunrong, Huang Zaitian, Xiao Zhenping, Sun Chenxun, Li Jingyu, He Fei, Han Bing, Zhu Chen

Cytoskeletal remodeling promotes tunneling nanotube formation and drives cardiac resident cell mitochondrial transfer in sepsis.

细胞骨架重塑促进隧道纳米管的形成,并驱动脓毒症中心脏驻留细胞线粒体的转移。

Hyodeoxycholic acid attenuates atherosclerosis by antagonizing FXR and modulating the PD-1/mTORC1 signaling axis.

脱氧胆酸通过拮抗 FXR 和调节 PD-1/mTORC1 信号轴来减轻动脉粥样硬化。

Yang Feng, Huang Wenqiong, Meng Zongzhen, Liu Meijun, Lyu Aiping, Mauro Claudio, Cheung Kenneth C P

Macrophage efferocytosis mediated by the TP63-RAC2 pathway promotes immunosuppressive remodeling in esophageal cancer.

TP63-RAC2通路介导的巨噬细胞吞噬作用促进食管癌的免疫抑制性重塑。

  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 23