Anti-IL-1 beta antibody [RM1009] (Ab283818)

特异性

IL-1 beta is not present under homeostatic conditions, and it is induced and secreted only upon inflammatory signals. Stimulation may be required for the detection of IL-1β, no matter in precursor or mature form (PMID: 22019906). IL-1β is a secreted protein, it is recommended to treat cells with anti-secretion reagents (e.g. Brefeldin A) when test IL-1β using whole cell lysate in WB. Please navigate to the Product Protocol section for specificity details in Chinese.

Product Specifications Anti-IL-1 beta antibody [RM1009] (ab283818) is a recombinant rabbit multiclonal antibody which is comprised of multiple monoclonal antibodies targeting different epitopes and recapitulating the performance of a polyclonal. Each component clone was developed by Abcam using patented rabbit monoclonal antibody technology. Anti-IL-1 beta antibody [RM1009] (ab283818) is validated for use in Flow Cyt, ICC, IHC-P, IP and WB in human, mouse and rat samples. Anti-IL-1 beta antibody [RM1009] (ab283818) specifically detects IL-1 beta/ Interleukin-1 beta (UniProt ID: P01584; Molecular weight: 31kDa) and is sold in a convenient trial size to enable initial testing (20 µL) and larger sizes for subsequent scaling up experiments (100 µL and 1 mL). Quality and Validation Abcams high quality manufacturing and validation processes ensure anti-IL-1 beta antibody [RM1009] (ab283818) has high sensitivity and specificity alongside high lot-to-lot consistency and reproducibility. The specificity of anti-IL-1 beta antibody [RM1009] (ab283818) has been confirmed by testing in knockout samples. Related Products Conjugation-ready, carrier free format available for antibody clone RM1009 - ab283822. What are recombinant multiclonals? Recombinant multiclonals are a mixture of recombinant antibodies co-expressed from a library of heavy and light chains. They offer several advantages including - The sensitivity of polyclonal antibodies by recognising multiple epitopes - High batch-to-batch consistency and reproducibility - Improved sensitivity and specificity - Long-term security of supply - Animal-free batch production View our range of recombinant multiclonal antibodies. Patented technology Our RabMAb ® technology is a patented hybridoma-based technology for making rabbit monoclonal antibodies. For details on our patents, please refer to RabMAb ® patents.