Anti-COX2 / Cyclooxygenase 2 antibody (Ab15191)
COX2, PTGS2, Prostaglandin G/H synthase 2, Cyclooxygenase-2, PHS II, Prostaglandin H2 synthase 2, Prostaglandin-endoperoxide synthase 2, COX-2, PGH synthase 2, PGHS-2
详细信息
背景信息
Product Specifications Anti-COX2 / Cyclooxygenase 2 antibody (ab15191) is a rabbit polyclonal antibody and is validated for use in IHC-P, WB, sELISA in human, mouse samples. Anti-COX2 / Cyclooxygenase 2 antibody (ab15191) specifically detects COX2 / Cyclooxygenase 2 (UniProt ID: P35355; Molecular weight: 67kDa) and is sold in 500 µL and 1 mL selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-COX2 / Cyclooxygenase 2 antibody (ab15191) has high sensitivity and specificity. Anti-COX2 / Cyclooxygenase 2 antibody (ab15191) has been cited over 427 times in peer reviewed journals and is trusted by the scientific community. Anti-COX2 / Cyclooxygenase 2 antibody (ab15191) has 37 independent reviews from customers. Target Information Cyclooxygenase-2 (COX-2) is an enzyme that plays a key role in the inflammatory response by converting arachidonic acid into prostaglandins, which mediate inflammation and pain. It is implicated in various diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders, due to its role in promoting inflammation and tumorigenesis
文献引用 (407)
Cyclooxygenase 2 (COX-2) expression is elevated in prefrontal cortex neurons, not microglia, following methamphetamine self-administration in male and female rats.
在雄性和雌性大鼠中，甲基苯丙胺自我给药后，环氧合酶 2 (COX-2) 的表达在前额皮质神经元中升高，而不是在小胶质细胞中升高。
GluN2A-NMDAR mediated neuronal NFκB activation plays a key role in exacerbating ischemic brain injury under hyperhomocysteinemic conditions.
GluN2A-NMDAR 介导的神经元 NFγB 激活在高同型半胱氨酸血症条件下加剧缺血性脑损伤中起关键作用。
Gpx4 Deletion-Mediated Macrophage Ferroptosis Alleviates Obesity-Associated Insulin Resistance.
Gpx4 缺失介导的巨噬细胞铁死亡可缓解肥胖相关的胰岛素抵抗。
Nuclear factor erythroid 2-related factor 2/heme oxygenase-1 activation by nattokinase reduces pro-inflammatory and matrix-degrading mediators in human gingival fibroblasts.
纳豆激酶激活核因子E2相关因子2/血红素加氧酶-1可减少人牙龈成纤维细胞中的促炎和基质降解介质。
Elevated PGE2 and COX-2 expression in villous adenoma: Implications for electrolyte depletion syndrome.
绒毛状腺瘤中 PGE2 和 COX-2 表达升高：对电解质耗竭综合征的意义。
Senescence-associated lysosomal dysfunction impairs cystine deprivation-induced lipid peroxidation and ferroptosis
衰老相关的溶酶体功能障碍会损害胱氨酸缺乏诱导的脂质过氧化和铁死亡。
The ubiquitin ligase Pellino1 targets STAT3 to regulate macrophage-mediated inflammation and tumor development
泛素连接酶 Pellino1 靶向 STAT3 来调节巨噬细胞介导的炎症和肿瘤发展
Activation of central and peripheral transient receptor potential melastatin 8 increases susceptibility to spreading depolarization and facilitates trigeminal neuroinflammation.
中枢和外周瞬时受体电位melastatin 8 的激活增加了对扩散性去极化的敏感性，并促进了三叉神经炎症
A Novel Function of Glycerol Kinase Alleviates LPS-Induced Inflammatory Responses by the p38/STAT3 Pathway and Mitigates ROS Generation in Kupffer Cells.
甘油激酶的新功能通过 p38/STAT3 通路减轻 LPS 诱导的炎症反应并减轻库普弗细胞中 ROS 的产生。
Combination of Ketorolac Tromethamine and Prednisolone-Loaded PLGA Nanocomposite for Effective Chronic Pain Relief in Mice.
酮咯酸氨丁三醇与泼尼松龙负载的PLGA纳米复合材料联合应用可有效缓解小鼠慢性疼痛
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