用户验证的应用
经验证应用
| 项目 | 详情 |
|---|---|
| IHC-P | 1:200-1:1000 |
推荐稀释说明
Optimal concentrations/dilutions should be determined by the end user.
详细信息
特异性
Human CD81
制备方法
Produced in rabbits immunized with E. coli-derived Human CD81 fragment, and purified by antigen affinity chromatography.
运输条件
This antibody is shipped as liquid solution at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
背景信息
CD81, also known as TAPA-1, belongs to the transmembrane 4 superfamily, also known as the tetraspanin family. Members of this family mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.CD81 is a widely expressed cell-surface protein involved in an astonishing variety of biologic responses. It is related to adhesion, morphology, activation, proliferation, and differentiation of B, T, and other cells. On B cells CD81 is part of a complex with CD21, CD19, and Leu13. This complex reduces the threshold for B cell activation via the B cell receptor by bridging Ag specific recognition and CD21-mediated complement recognition. Full Name CD81 molecule References Petracca R. et al., 2000, J Virol. 74 (10): 4824-30. Bartosch B. et al., 2003, The Journal of Biological Chemistry. 278 (43): 41624-30. Clark KL. et al., 2001, Journal of Immunology. 167 (9): 5115-21.