Anti-Lamin B1 antibody - Nuclear Envelope Marker (Ab16048)
LMN2, LMNB, LMNB1, Lamin-B1
详细信息
特异性
From July 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help.
背景信息
Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-P and WB. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) was first used in a scientific publication in 1997 and has been cited over 1182 times in peer reviewed journals. It's performance in Western blot and immunofluorescence in human, mouse and rat samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has high sensitivity and specificity. The specificity of Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has been confirmed by ICC/IF testing in Lamin B1 knockout HAP1 cells. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) has 108 independent reviews from customers. Anti-Lamin B1 antibody - Nuclear Envelope Marker (ab16048) specifically detects Lamin B1 (UniProt ID: P14733; Molecular weight: 67kDa) and is sold in 100 ug selling sizes. Top cited with >1500 citations. Lamin B1 is essential for studying nuclear envelope structure and function, as well as investigating diseases like laminopathies and certain cancers
文献引用 (1376)
Short-chain acyl-CoA dehydrogenase initiates mtDNA demethylation and leakage to fuel antitumor immunity in colorectal cancer.
短链酰基辅酶A脱氢酶启动线粒体DNA去甲基化和泄漏,从而促进结直肠癌的抗肿瘤免疫。
Androgen activity in the male embryonic hindbrain drives lethal PFA ependymoma.
雄性胚胎后脑中的雄激素活性会引发致命的 PFA 室管膜瘤。
Inducible CD147 up-regulation boosts extended SARS-CoV-2 infection triggering severe COVID-19 independent of ACE2
诱导型 CD147 上调可延长 SARS-CoV-2 感染,并引发重症 COVID-19,且该过程独立于 ACE2。
Transient histone deacetylase inhibition induces cellular memory of gene expression and 3D genome folding.
瞬时组蛋白去乙酰化酶抑制可诱导细胞对基因表达和 3D 基因组折叠的记忆。
DNA damage in macrophages drives immune autoreactivity via nuclear antigen presentation.
巨噬细胞中的DNA损伤通过核抗原呈递驱动免疫自身反应。
Comparative analysis of senolytic drugs reveals mitochondrial determinants of efficacy and resistance.
对衰老细胞清除药物的比较分析揭示了线粒体对药物疗效和耐药性的决定因素。
Impaired nucleocytoplasmic transport in SOD1-mediated ALS.
SOD1介导的ALS中核质转运受损。
ER-tethering directs TREX1 penetration of a BAF-dependent barrier at micronuclei.
内质网锚定引导 TREX1 穿透微核处 BAF 依赖性屏障。
Mechanical rejuvenation of senescent stem cells and aged bone via chromatin remodeling.
通过染色质重塑实现衰老干细胞和老化骨骼的机械再生。
RNA-coupled CRISPR screens reveal ZNF207 as a regulator of LMNA aberrant splicing in progeria
RNA偶联CRISPR筛选揭示ZNF207是早衰症中LMNA异常剪接的调节因子
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