Anti-COX IV antibody - Mitochondrial Loading Control (Ab16056)

Product Specifications Anti-COX IV antibody - Mitochondrial Loading Control (ab16056) is a rabbit polyclonal antibody and is validated for use in ICC/IF, IHC-Fr, IHC-P, WB in african green monkey, chinese hamster, human, mouse, potato, rat, xenopus laevis samples. COX IV antibodies are often used as loading controls in Western Blot. Anti-COX IV antibody - Mitochondrial Loading Control has been verified in Western Blot samples and detects a band at 17kDa Molecular weight. Anti-COX IV antibody - Mitochondrial Loading Control (ab16056) specifically detects COX IV (UniProt ID: P13073; Molecular weight: 17kDa) and is sold in 100 µg and 250 µg selling sizes. Quality and Validation Abcam's high quality validation processes ensure Anti-COX IV antibody - Mitochondrial Loading Control (ab16056) has high sensitivity and specificity. Anti-COX IV antibody - Mitochondrial Loading Control (ab16056) has been cited over 272 times in peer reviewed journals and is trusted by the scientific community. Anti-COX IV antibody - Mitochondrial Loading Control (ab16056) has 32 independent reviews from customers. Target Information COX IV, also known as cytochrome c oxidase, is a critical mitochondrial enzyme involved in oxidative phosphorylation and the respiratory chain. The COX IV molecular weight is approximately 17 kDa. Dysfunction in COX IV is linked to mitochondrial disorders and neurodegenerative diseases, highlighting its disease relevance. Understanding COX IV's role in key pathways, such as electron transport and ATP synthesis, is essential for developing targeted therapies for these conditions. This antibody makes an effective loading control for mitochondria. COX IV is generally expressed at a consistent high level. However, be aware that many proteins run at the same 16kD size as COX IV - our VDAC1 / Porin antibody makes a good alternative mitochondrial loading control for proteins of this size. Some caution is required when using this antibody as a loading control as COXIV expression can vary under some manipulations. An alternative mitochondrial loading control is Mouse monoclonal to COX IV antibody [20E8] ( ab14744 ).