Anti-HIF-1 alpha antibody [mgc3] (Ab16066)

BHLHE78, MOP1, PASD8, HIF1A, Hypoxia-inducible factor 1-alpha, HIF-1-alpha, HIF1-alpha, ARNT-interacting protein, Basic-helix-loop-helix-PAS protein MOP1, Class E basic helix-loop-helix protein 78, Member of PAS protein 1, PAS domain-containing protein 8, bHLHe78

反应种属:Human
抗原名称:HIF1A
应用:WB, IHC, FCM

详细信息

免疫原Recombinant Fragment Protein within Human HIF1A aa 500-850. The exact immunogen used to generate this antibody is proprietary information. Q16665
宿主/亚型Mouse / IgG1
抗体类型Monoclonal
产品形式Liquid
纯化方式Affinity purification Protein G
储存缓冲液pH: 7.4 Preservative: 0.05% Sodium azide Constituents: 0.1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle

特异性

This antibody does not cross-react with ARNT or the related HIF-2-alpha.

背景信息

What is this antibody validated in? Anti-HIF-1 alpha antibody [mgc3] (ab16066) is a mouse monoclonal antibody and is validated for use in Western Blot (WB), Flow Cytometry (Flow Cyt), Immunohistochemistry (IHC-P) in Human samples. What is the molecular weight of HIF-1 alpha? Anti-HIF-1 alpha [mgc3] (ab16066) specifically detects a band for HIF-1 alpha (UniProt: Q16665) at a molecular weight of 92kDa. Trusted by the scientific community Anti-HIF-1 alpha [mgc3] (ab16066) was first used in a scientific publication in 2004 and has been cited over 140 times in peer-reviewed journals. Reviewed by scientists Anti-HIF-1 alpha [mgc3] (ab16066) has over 10 independent reviews from customers.

文献引用 (137)

Glycolytic heterogeneity drives metabolic-targeted therapy in pancreatic ductal adenocarcinoma.

胰腺导管腺癌的代谢靶向治疗依赖于糖酵解异质性。

Chianese Ugo, Papulino Chiara, Saggese Gerardo, Ali Ahmad, Ciotola Marianna, Lonardo Enza, Cortese Mirko, Favale Gregorio, Di Mauro Annabella, La Gioia Danila, Golino Valentina, Sommella Eduardo, Campiglia Pietro, Franco Renato, Ciardiello Fortunato, De Vita Ferdinando, Carafa Vincenzo, Altucci Lucia, Benedetti Rosaria

Cellular senescence in human liver under normal aging and cancer.

正常衰老和癌症下人类肝脏细胞衰老。

Modulation of breast cancer progression in high-altitude hypoxia by Tongqiaohuoxue Decoction via HIF-1α/VEGF signaling.

通桥活血汤通过 HIF-1α/VEGF 信号通路调节高海拔缺氧条件下乳腺癌的进展。

Yang Wenke, Wang Qiang, Yang Quanyu, Peng Yan, Gao Yi, Yang Huaxiucairang, Lan Wenguang, Zhang Ting, Zhang Shoude, Su Zhanhai, Zhao Xiaohui, Ma Xueman

Semaphorin 7A Regulates the Balance Between Cartilaginous and Fibrous Tissues in the Repair Process of Articular Cartilage Damage.

信号素 7A 调节关节软骨损伤修复过程中软骨组织和纤维组织之间的平衡。

Hatada Ryosuke, Abe Kengo, Yamashita Akihiro, Horike Nanao, Obata Sho, Kumanogoh Atsushi, Matsuda Shuichi, Tsumaki Noriyuki

Olverembatinib, a multikinase inhibitor that modulates lipid metabolism, in advanced succinate dehydrogenase-deficient gastrointestinal stromal tumors: a phase 1b study and translational research.

Olverembatinib 是一种调节脂质代谢的多激酶抑制剂,用于治疗晚期琥珀酸脱氢酶缺乏型胃肠道间质瘤:一项 1b 期研究和转化研究。

Qiu Hai-Bo, Liang Zhiyan, Yang Jing, Zhou Ye, Zhou Zhi-Wei, Wan Xiang-Bin, Li Ning, Tao Kai-Xiong, Li Yong, Wu Xin, Yang Chen, Chen Zi, Wang Hengbang, Men Lichuang, Xiong Yan, Liu Lihui, Yang Dajun, Zhai Yifan, Xu Rui-Hua

Tumors hijack macrophages for iron supply to promote bone metastasis and anemia

肿瘤劫持巨噬细胞获取铁,从而促进骨转移和贫血。

Yujiao Han ,Hirak Sarkar ,Zhan Xu ,Sereno Lopez-Darwin ,Yong Wei ,Xiang Hang ,Fengshuo Liu ,Kimberley Tran ,Wei Wang ,Jennifer M Miller ,Christina J DeCoste ,Dylan S Blohm ,Robert L Satcher ,Xiang H-F Zhang ,Yibin Kang

Challenges in mimicking hypoxia: insights into HIF-regulated MiRNA expression induced by DMOG and CoCl(2).

模拟缺氧的挑战:深入了解 DMOG 和 CoCl(2) 诱导的 HIF 调控的 miRNA 表达。

Barton Anna, Jaśkiewicz Maciej, Więch-Walów Anna, Moszyńska Adrianna, Cabaj Aleksandra, Wielockx Ben, Schaefer Liliana, Collawn James F, Bartoszewski Rafal

HOXA9 drives lymphatic metastasis by activating the c-MYC-glycolysis-lactate axis in gastric cancer.

HOXA9 通过激活胃癌中的 c-MYC-糖酵解-乳酸轴来驱动淋巴转移。

Lu Tailiang, Shen Guodong, Huang Tao, Mao Xinyuan, He Junting, Hu Yanfeng

Hypoxia Regulates the Proliferation and Apoptosis of Coronary Artery Smooth Muscle Cells Through HIF-1α Mediated Autophagy in Yak

低氧通过HIF-1α介导自噬调控牦牛冠状动脉平滑肌细胞增殖与凋亡

Shanshan Yang, Yan Cui, Rui Ma, Sijiu Yu, Hui Zhang, Pengfei Zhao, Junfeng He

Multi-cellular phenotypic dynamics during the progression of an immunocompetent breast cancer model

免疫活性乳腺癌模型进展过程中的多细胞表型动态

Louise Gsell,Spencer S Watson,Iva Sutevski,Matteo Massara,Klara Soukup,Alper Eroglu,Jeff E Mold,Antony Cougnoux,Johanna A Joyce,Jean Hausser
  • 1
  • 2
  • 3
  • 4
  • 5
  • 6
  • 14