Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (Ab1791)

H3FA, HIST1H3A, H3C2, H3FL, HIST1H3B, H3C3, H3FC HIST1H3C, H3C4, H3FB, HIST1H3D, H3C6, H3FD, HIST1H3E, H3C7, H3FI, HIST1H3F, H3C8, H3FH, HIST1H3G, H3C10, H3FK, HIST1H3H, H3C11, H3FF, HIST1H3I, H3C12, H3FJ, HIST1H3J, HIST1H3C, H3FC, H3C1, Histone H3.1, Histone H3/a, Histone H3/b, Histone H3/c, Histone H3/d, Histone H3/f, Histone H3/h, Histone H3/i, Histone H3/j, Histone H3/k, Histone H3/l

反应种属:Human, Mouse, Rat, Arabidopsis, Drosophila, Yeast, Indian muntjac, Xenopus laevis
抗原名称:H3C1
应用:WB, IHC, IF/ICC, IP, ChIP

用户验证的应用

推荐稀释比例

  • WB1/1000 - 1/5000 We recommend Goat Anti-Rabbit IgG H&L (HRP) ( ab6721 ) secondary antibody.
  • ICC/IF1 µg/mL
  • ChIP2 µg for 10^6 Cells

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
全称Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade
产品形式Liquid
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
纯化方式Affinity purification Immunogen

背景信息

Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) is a rabbit polyclonal antibody and is validated for use in ChIP, ICC/IF, IHC-P, IP and WB. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) was first used in a scientific publication in 1987 and has been cited over 4739 times in peer reviewed journals. It's performance in Western blot and ChIP in human and mouse samples is trusted by the scientific community. Abcam's high quality validation processes ensure Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) has high sensitivity and specificity. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) has 230 independent reviews from customers. Anti-Histone H3 antibody - Nuclear Marker and ChIP Grade (ab1791) specifically detects Histone H3 (UniProt ID: P68431; Molecular weight: 16kDa) and is sold in 100 µg and 250 µg selling sizes. Top cited antibody for this target with >5000 citations and >150 five star abreviews. Key marker for researchers studying chromatin structure, epigenetic regulation and histone modifications. This antibody can use used as a control in cancer research, particularly in understanding histone mutations in various tumors and is widely used in studies of gene expression, DNA repair and cell cycle regulation.

文献引用 (5014)

An ATP-gated molecular switch orchestrates human mRNA export.

ATP门控分子开关调控人类mRNA的输出。

Hohmann Ulrich, Graf Max, Tirián László, Pacheco-Fiallos Belén, Schellhaas Ulla, Fin Laura, Handler Dominik, Phillips Alexander W, Riabov-Bassat Daria, Faraway Rupert, Pühringer Thomas, Szalay Michael-Florian, Roitinger Elisabeth, Brennecke Julius, Plaschka Clemens

Live-cell single-molecule dynamics of eukaryotic RNA polymerase machineries.

真核生物RNA聚合酶机制的活细胞单分子动力学。

Ling Yick Hin, Liang Chloe, Wang Sixiang, Wu Carl

CRISPR screen of human pancreatic cancer xenografts identifies a KLF5 proliferation vulnerability through epigenetic modifiers NCAPD2 and MTHFD1.

通过 CRISPR 筛选人类胰腺癌异种移植瘤,发现 KLF5 增殖脆弱性与表观遗传修饰因子 NCAPD2 和 MTHFD1 有关。

Maeda Masahiro, Sherman Kenna, Zhou Weiqiang, Cheng Jiaqi, Nihongaki Yuta, Idrizi Adrian, Tryggvadottir Rakel, Camacho Oscar, Shang Xingbo, Min Jimin, Koldobskiy Michael A, Maitra Anirban, Levchenko Andre, Slusher Barbara S, Ji Hongkai, Feinberg Andrew P

CBFA2T2: a novel H3K27 reader regulating metabolism and tumor growth.

CBFA2T2:一种新型的 H3K27 阅读器,可调节代谢和肿瘤生长。

He Shengfei, Ou Yutian, Jiao Fangfang, Feng Jiuxing, Zhu Ping, Ma Jie, Xu Ning, Li Haitao, Guo Rui

Epigenetic Regulation of Chromosomal Instability by EZH2 Methyltransferase.

EZH2甲基转移酶对染色体不稳定性进行表观遗传调控。

Bai Yang, Agustinus Albert S, Yomtoubian Shira, Meydan Cem, McNally Dylan R, Yoffe Liron, Hubisz Melissa J, Tranquille Marvel, Pramod Sneha, Hong Christy, Plasilova Magdalena L, Kapoor Aakanksha R, Singh Arshdeep, Withers Henry, Dow Lukas E, Laughney Ashley M, Bhinder Bhavneet, Elemento Olivier, Melnick Ari M, Bakhoum Samuel F, Mittal Vivek

Natural variation in OsTPS8 confers differential regulation of chalkiness and seed vigor in indica and japonica rice.

OsTPS8 的自然变异赋予籼稻和粳稻垩白度和种子活力差异性调控。

Chen Xiaoli, Ren Yulong, Dong Hui, Jiang Xiaokang, Zheng Xiaoming, Duan Erchao, Teng Xuan, Wang Yunlong, Gu Chuanwei, Chen Rongbo, Wang Qingkai, Wang Yongfei, Zhang Yipeng, Zhang Rushuang, Zhang Yunpeng, Zhao Wenjie, Zhang Yu, Yang Xue, Zhou Lei, Li Chao, Shan Tiaofeng, Bao Yiqun, Tian Yunlu, Liu Xi, Liu Shijia, Guo Tao, Chen Mingjiang, Wang Haiyang, Wang Yihua, Wan Jianmin

Nonsense-mediated mRNA decay safeguards telomeres in pluripotent stem cells.

无义介导的mRNA衰变保护多能干细胞中的端粒。

Markiewicz-Potoczny Marta, Lee Si Young, Chatterjee Soniya, Mabin Justin W, Zinsser Anna, Sandhu Ranjodh, Tricola Gianna, Hogg J Robert, Lazzerini Denchi Eros

Palmitoylation-mediated regulation of KAT2A promotes lung metastasis in breast cancer.

棕榈酰化介导的 KAT2A 调控促进乳腺癌肺转移。

Liu Ming, Vandekeere Anke, Liu Xiao-Zheng, Schenck Stephan, Fernández-García Juan, Tricot Tine, Peng-Winkler Yiming, Demicco Margherita, Broekaert Dorien, Vermeire Ines, Theile Janine, Zels Gitte, Pabba Anirudh, Desmedt Christine, Brunner Janine D, Altea-Manzano Patricia, Fendt Sarah-Maria

DOT1L provides transcriptional memory through PRC1.1 antagonism.

DOT1L 通过 PRC1.1 拮抗作用提供转录记忆。

Unbalanced chromatin binding of Polycomb complexes drives neurodevelopmental disorders.

Polycomb复合物与染色质结合失衡会导致神经发育障碍。

Borges Rodrigo L, González-Blanco Gretter, Arigela Harikumar, Huang Yingyu, Caeiro Lucas D, Fattakhov Nikolai, Lepore Stefano, Garcia-Martinez Liliana, Maurice Matea, Mehta Pushti D, Park Emily J, MacGillivray Kailynn, Nehru Jevithen, Chau Matthew, Robayo Maria C, Abad Clemer, Bilbao-Martinez Alicia, Monteiro Fabiola, Luo Xi, Tan Song, Bilbao Daniel, Sidoli Simone, Di Stefano Bruno, Walz Katherina, Saltzman Arneet L, Verdun Ramiro E, Shiekhattar Ramin, Morey Lluis
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