Anti-Actin antibody - Loading Control (Ab1801)

ACTA, ACTA1, Alpha-actin-1

反应种属:Human, Mouse, Rat
抗原名称:ACTA1
应用:WB, IHC

详细信息

免疫原The exact immunogen used to generate this antibody is proprietary information.
宿主/亚型Rabbit / IgG
抗体类型Polyclonal
产品形式Liquid
纯化方式Affinity purification Immunogen
储存缓冲液pH: 7.4 Preservative: 0.02% Sodium azide Constituents: PBS, 1% BSA
储存条件运输条件: Blue Ice 推荐的短期储存时间: 1-2 weeks 推荐的短期储存条件: +4°C 推荐的长期储存条件: -20°C 储存信息: Avoid freeze / thaw cycle
无载体蛋白No

特异性

From Jan 2024, QC testing of replenishment batches of this polyclonal changed. All tested and expected application and reactive species combinations are still covered by our Abcam product promise. However, we no longer test all applications. For more information on a specific batch, please contact our Scientific Support who will be happy to help. This antibody recognises beta and gamma actin in Human samples. It probably also recognises all the other known forms of Human actin. This antibody detects a single clean band in Human, Mouse, Rat, Chicken and Drosophila samples. In Xenopus laevis a secondary band is detected at about 30kDa. We are unsure whether this is cross-reaction with another actin isoform or merely non-specific. In Cow a doublet is detected, which probably represents different forms of actin.

文献引用 (200)

Upregulation of Parathyroid Hormone Receptor 1 (PTH1R) in Non-Mechanostimulated Osteocytes Under High-Glucose Conditions Promotes a Macrophage Pro-Inflammatory and Osteoclastogenic Phenotype via IL-6 Secretion

高糖条件下非机械刺激骨细胞中甲状旁腺激素受体1(PTH1R)的上调通过IL-6分泌促进巨噬细胞的促炎和破骨细胞生成表型

Irene Tirado-Cabrera,Joan Pizarro-Gomez,Eduardo Martin-Guerrero,Celia Méndez-Rodríguez,Teresita Bellido,Arancha R Gortazar,Juan A Ardura

The SWI/SNF-related protein SMARCA3 is a histone H3K23 ubiquitin ligase that regulates H3K9me3 in cancer.

SWI/SNF 相关蛋白 SMARCA3 是一种组蛋白 H3K23 泛素连接酶,可调节癌症中的 H3K9me3

Akano Ifé, Hebert Jakob M, Tiedemann Rochelle L, Gao Qingzeng, Xiao Yang, Prescott Nicholas A, Liu Yanqing, Tan Kay See, Bastle Ryan M, Ramakrishnan Aarthi, Maze Ian, Sidoli Simone, Koche Richard P, Ganesh Karuna, Rothbart Scott B, David Yael

Enhancing autophagy by redox regulation extends lifespan in Drosophila.

通过氧化还原调节增强自噬可延长果蝇的寿命

Lennicke Claudia, Bjedov Ivana, Grönke Sebastian, Menger Katja E, James Andrew M, Castillo-Quan Jorge Iván, van Leeuwen Lucie A G, Foley Andrea, Buricova Marcela, Adcott Jennifer, Montoya Alex, Kramer Holger B, Shliaha Pavel V, Logan Angela, Cabreiro Filipe, Murphy Michael P, Partridge Linda, Cochemé Helena M

Activated microglial exosomes enhance α-Synuclein internalization and accelerate neurodegeneration in lewy body dementia.

活化的微胶质细胞外泌体增强α-突触核蛋白的内化,加速路易体痴呆症的神经退行性变。

Zhang Minjie, You Tongyao, Guo Min, Zhao Yichen, Shen Weiwei, Wang Yingzhe, Jiang Yanfeng, Dong Qiang, Yu Jintai, Cui Mei, Zhao Yanxin

Obestatin treatment links mitochondrial homeostasis and skeletal muscle repair in Duchenne muscle dystrophy.

奥贝斯汀治疗将杜氏肌营养不良症的线粒体稳态与骨骼肌修复联系起来。

Lodeiro Andrea C, Costas-Abalde Silvia, Cid-Díaz Tania, Debasa-Corral Lucía, Leal-López Saúl, Mamchaoui Kamel, Mouly Vincent, Casabiell Xesús, Gallego Rosalía, Relova José Luis, Pazos Yolanda, Santos-Zas Icía, Camiña Jesus P

MPS1 promotes timely spindle bipolarization to prevent kinetochore-microtubule attachment errors in oocytes.

MPS1 促进纺锤体及时双极化,以防止卵母细胞中动粒-微管连接错误

Yoshida Shuhei, Nakagawa Reiko, Asai Kohei, Kitajima Tomoya S

Integrated Bioinformatics and Experimental Analysis Revealed Crosstalk Between IL-6, Autophagy, Ubiquitination, and Key miRNAs in Female Infertility: Insights from Ovarian Endometriosis and Polycystic Ovary Syndrome.

整合生物信息学和实验分析揭示了IL-6、自噬、泛素化和关键miRNA在女性不孕症中的相互作用:来自卵巢子宫内膜异位症和多囊卵巢综合征的启示。

Nahdi Saber, Arafah Maria, Harrath Abdel Halim

Role of ferroptosis-related GPX4 signaling in the fusion of human trophoblast cells.

铁死亡相关GPX4信号在人类滋养层细胞融合中的作用。

Yoshida Kanoko, Kusama Kazuya, Sato Shiho, Kawaguchi Yu, Horiuchi Ayaka, Yoshie Mikihiro, Tamura Kazuhiro

Knockdown of mitochondrial sirtuin sir-2.2 reduces alpha-synuclein clearance and impairs energy homeostasis in a model of ageing.

线粒体 sirtuin sir-2.2 的敲除会降低 α-突触核蛋白的清除率,并损害衰老模型中的能量稳态。

Naseer Anam, Toppo Pranoy, Akbar Mahmood, Nazir Aamir

FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins

FEAR抗病毒反应通路不依赖于干扰素,并会被痘病毒蛋白拮抗。

Emily A Rex ,Dahee Seo ,Sruthi Chappidi ,Chelsea Pinkham ,Sabrynna Brito Oliveira ,Aaron Embry ,David Heisler ,Yang Liu ,Moiz Munir ,Karolin Luger ,Neal M Alto ,Flávio Guimarães da Fonseca ,Robert Orchard ,Dustin C Hancks ,Don B Gammon
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